MCL coexpression mm9:3121
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr17:85025798..85025852,+ | p1@Dync2li1 |
| Mm9::chr5:122714387..122714464,- | p1@Tctn1 |
| Mm9::chr6:55153375..55153453,+ | p1@Fam188b |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0021956 | central nervous system interneuron axonogenesis | 0.00315507654069492 |
| GO:0007389 | pattern specification process | 0.00315507654069492 |
| GO:0032990 | cell part morphogenesis | 0.00315507654069492 |
| GO:0030030 | cell projection organization and biogenesis | 0.00315507654069492 |
| GO:0048858 | cell projection morphogenesis | 0.00315507654069492 |
| GO:0021523 | somatic motor neuron differentiation | 0.00405390596887041 |
| GO:0021904 | dorsoventral neural tube patterning | 0.00442207940659197 |
| GO:0000902 | cell morphogenesis | 0.00442207940659197 |
| GO:0032989 | cellular structure morphogenesis | 0.00442207940659197 |
| GO:0021517 | ventral spinal cord development | 0.00442207940659197 |
| GO:0021522 | spinal cord motor neuron differentiation | 0.00442207940659197 |
| GO:0021515 | cell differentiation in spinal cord | 0.00472903868446856 |
| GO:0021532 | neural tube patterning | 0.00498873928580061 |
| GO:0021955 | central nervous system neuron axonogenesis | 0.00521130806984765 |
| GO:0008589 | regulation of smoothened signaling pathway | 0.00648465028861927 |
| GO:0021510 | spinal cord development | 0.00658579247715281 |
| GO:0042384 | cilium biogenesis | 0.0066750094529573 |
| GO:0021954 | central nervous system neuron development | 0.00945444941444193 |
| GO:0021537 | telencephalon development | 0.00972377690978215 |
| GO:0021953 | central nervous system neuron differentiation | 0.00972377690978215 |
| GO:0007224 | smoothened signaling pathway | 0.0108030119282221 |
| GO:0009653 | anatomical structure morphogenesis | 0.0113409857519361 |
| GO:0007368 | determination of left/right symmetry | 0.0113409857519361 |
| GO:0009855 | determination of bilateral symmetry | 0.0113409857519361 |
| GO:0009799 | determination of symmetry | 0.0113409857519361 |
| GO:0009953 | dorsal/ventral pattern formation | 0.0133943795193287 |
| GO:0030031 | cell projection biogenesis | 0.0143961183162794 |
| GO:0001841 | neural tube formation | 0.0148858579396324 |
| GO:0001839 | neural plate morphogenesis | 0.0148858579396324 |
| GO:0001840 | neural plate development | 0.0148858579396324 |
| GO:0001838 | embryonic epithelial tube formation | 0.0148858579396324 |
| GO:0021915 | neural tube development | 0.0164410198034808 |
| GO:0016331 | morphogenesis of embryonic epithelium | 0.0179010678781001 |
| GO:0048856 | anatomical structure development | 0.0231036180869506 |
| GO:0030900 | forebrain development | 0.0231036180869506 |
| GO:0001701 | in utero embryonic development | 0.0265317845739987 |
| GO:0002009 | morphogenesis of an epithelium | 0.0265317845739987 |
| GO:0007275 | multicellular organismal development | 0.0265317845739987 |
| GO:0003002 | regionalization | 0.0291509628980074 |
| GO:0016043 | cellular component organization and biogenesis | 0.0291509628980074 |
| GO:0035239 | tube morphogenesis | 0.0291509628980074 |
| GO:0007409 | axonogenesis | 0.0296056635183185 |
| GO:0048667 | neuron morphogenesis during differentiation | 0.0299041014782157 |
| GO:0048812 | neurite morphogenesis | 0.0299041014782157 |
| GO:0007420 | brain development | 0.0324449225963009 |
| GO:0000904 | cellular morphogenesis during differentiation | 0.0324449225963009 |
| GO:0031175 | neurite development | 0.0330781690028371 |
| GO:0048598 | embryonic morphogenesis | 0.0330781690028371 |
| GO:0035295 | tube development | 0.0330781690028371 |
| GO:0032502 | developmental process | 0.0340595106086465 |
| GO:0048666 | neuron development | 0.0340595106086465 |
| GO:0043009 | chordate embryonic development | 0.0340595106086465 |
| GO:0009792 | embryonic development ending in birth or egg hatching | 0.0340595106086465 |
| GO:0007417 | central nervous system development | 0.0344667770223854 |
| GO:0030182 | neuron differentiation | 0.0405273721558926 |
| GO:0048699 | generation of neurons | 0.0452166221412793 |
| GO:0009966 | regulation of signal transduction | 0.0466591344530326 |
| GO:0022008 | neurogenesis | 0.0468153418192806 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| ectodermal cell | 3.19e-09 | 44 |
| neurectodermal cell | 3.19e-09 | 44 |
| non-terminally differentiated cell | 4.78e-09 | 49 |
| neural cell | 9.99e-09 | 43 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.245953 |
| MA0004.1 | 0.801718 |
| MA0006.1 | 0.60285 |
| MA0007.1 | 0.784593 |
| MA0009.1 | 1.27673 |
| MA0014.1 | 0.416365 |
| MA0017.1 | 0.635031 |
| MA0019.1 | 1.08369 |
| MA0024.1 | 1.23079 |
| MA0025.1 | 1.51835 |
| MA0027.1 | 2.9431 |
| MA0028.1 | 0.61552 |
| MA0029.1 | 1.20789 |
| MA0030.1 | 1.21482 |
| MA0031.1 | 1.17722 |
| MA0038.1 | 0.963265 |
| MA0040.1 | 1.28983 |
| MA0041.1 | 1.69964 |
| MA0042.1 | 0.69885 |
| MA0043.1 | 1.3775 |
| MA0046.1 | 1.31428 |
| MA0048.1 | 0.353763 |
| MA0050.1 | 0.845669 |
| MA0051.1 | 0.973068 |
| MA0052.1 | 1.29825 |
| MA0055.1 | 1.06076 |
| MA0056.1 | 0 |
| MA0057.1 | 0.337566 |
| MA0058.1 | 0.690848 |
| MA0059.1 | 0.705317 |
| MA0060.1 | 0.502699 |
| MA0061.1 | 0.5406 |
| MA0063.1 | 0 |
| MA0066.1 | 0.951196 |
| MA0067.1 | 1.63197 |
| MA0068.1 | 0.908538 |
| MA0069.1 | 1.29861 |
| MA0070.1 | 1.28847 |
| MA0071.1 | 0.844726 |
| MA0072.1 | 1.2796 |
| MA0073.1 | 0.121346 |
| MA0074.1 | 0.911576 |
| MA0076.1 | 0.657929 |
| MA0077.1 | 1.2569 |
| MA0078.1 | 1.0091 |
| MA0081.1 | 0.732313 |
| MA0083.1 | 1.37668 |
| MA0084.1 | 1.96428 |
| MA0087.1 | 1.33189 |
| MA0088.1 | 1.40099 |
| MA0089.1 | 0 |
| MA0090.1 | 0.762482 |
| MA0091.1 | 0.816659 |
| MA0092.1 | 1.80015 |
| MA0093.1 | 0.62555 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.89873 |
| MA0101.1 | 0.71579 |
| MA0103.1 | 0.647985 |
| MA0105.1 | 0.405648 |
| MA0106.1 | 1.01755 |
| MA0107.1 | 0.640607 |
| MA0108.2 | 1.10817 |
| MA0109.1 | 0 |
| MA0111.1 | 0.778753 |
| MA0113.1 | 0.986839 |
| MA0114.1 | 0.537669 |
| MA0115.1 | 1.38041 |
| MA0116.1 | 0.602598 |
| MA0117.1 | 1.34691 |
| MA0119.1 | 0.716476 |
| MA0122.1 | 1.36752 |
| MA0124.1 | 1.57762 |
| MA0125.1 | 1.5017 |
| MA0130.1 | 0 |
| MA0131.1 | 1.07881 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.4152 |
| MA0136.1 | 0.933582 |
| MA0139.1 | 0.462282 |
| MA0140.1 | 0.898603 |
| MA0141.1 | 0.671467 |
| MA0142.1 | 1.16183 |
| MA0143.1 | 1.00467 |
| MA0144.1 | 1.33779 |
| MA0145.1 | 0.292366 |
| MA0146.1 | 0.900029 |
| MA0147.1 | 1.37022 |
| MA0148.1 | 0.820161 |
| MA0149.1 | 0.722227 |
| MA0062.2 | 0.412742 |
| MA0035.2 | 0.903829 |
| MA0039.2 | 0.71803 |
| MA0138.2 | 1.07027 |
| MA0002.2 | 0.466067 |
| MA0137.2 | 0.668025 |
| MA0104.2 | 1.21648 |
| MA0047.2 | 0.962424 |
| MA0112.2 | 0.29236 |
| MA0065.2 | 0.292912 |
| MA0150.1 | 0.784464 |
| MA0151.1 | 0 |
| MA0152.1 | 0.962542 |
| MA0153.1 | 1.43238 |
| MA0154.1 | 0.35067 |
| MA0155.1 | 0.312898 |
| MA0156.1 | 0.656895 |
| MA0157.1 | 1.12772 |
| MA0158.1 | 0 |
| MA0159.1 | 0.569393 |
| MA0160.1 | 0.823568 |
| MA0161.1 | 0 |
| MA0162.1 | 0.499274 |
| MA0163.1 | 0.477233 |
| MA0164.1 | 0.933981 |
| MA0080.2 | 0.64167 |
| MA0018.2 | 0.944669 |
| MA0099.2 | 1.06348 |
| MA0079.2 | 0.288542 |
| MA0102.2 | 2.01714 |
| MA0258.1 | 0.520639 |
| MA0259.1 | 0.543506 |
| MA0442.1 | 0 |
