Personal tools

MCL coexpression mm9:1742

From FANTOM5_SSTAR

Jump to: navigation, search


Phase1 CAGE Peaks

 Short description
Mm9::chr1:138850177..138850182,-p11@Nr5a2
Mm9::chr2:120926896..120926901,-p@chr2:120926896..120926901
-
Mm9::chr5:102088225..102088234,+p@chr5:102088225..102088234
+
Mm9::chr5:102094214..102094230,-p1@Nkx6-1
Mm9::chr7:31238807..31238830,-p@chr7:31238807..31238830
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0014015positive regulation of gliogenesis0.0122007989608258
GO:0045687positive regulation of glial cell differentiation0.0122007989608258
GO:0043565sequence-specific DNA binding0.0122007989608258
GO:0014014negative regulation of gliogenesis0.0122007989608258
GO:0045686negative regulation of glial cell differentiation0.0122007989608258
GO:0031018endocrine pancreas development0.0122007989608258
GO:0045685regulation of glial cell differentiation0.0122007989608258
GO:0014013regulation of gliogenesis0.0122007989608258
GO:0008206bile acid metabolic process0.0132544626031471
GO:0031016pancreas development0.0137035799856242
GO:0042632cholesterol homeostasis0.0137035799856242
GO:0055088lipid homeostasis0.0137035799856242
GO:0055092sterol homeostasis0.0137035799856242
GO:0003700transcription factor activity0.0137035799856242
GO:0010001glial cell differentiation0.0260005569320371
GO:0042063gliogenesis0.0260005569320371
GO:0045597positive regulation of cell differentiation0.0260005569320371
GO:0003707steroid hormone receptor activity0.0260005569320371
GO:0004879ligand-dependent nuclear receptor activity0.0260005569320371
GO:0035270endocrine system development0.0260005569320371
GO:0051094positive regulation of developmental process0.0355754965155316
GO:0045596negative regulation of cell differentiation0.0374986713342052
GO:0006355regulation of transcription, DNA-dependent0.0374986713342052
GO:0006351transcription, DNA-dependent0.0374986713342052
GO:0032774RNA biosynthetic process0.0374986713342052
GO:0003677DNA binding0.0374986713342052
GO:0045449regulation of transcription0.0374986713342052
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0374986713342052
GO:0006350transcription0.0374986713342052
GO:0051093negative regulation of developmental process0.0374986713342052
GO:0010468regulation of gene expression0.0383624089928053
GO:0031323regulation of cellular metabolic process0.0402726768672539
GO:0019222regulation of metabolic process0.0419935832871114
GO:0016070RNA metabolic process0.0429385142340032
GO:0008202steroid metabolic process0.0432249066404042
GO:0045595regulation of cell differentiation0.0459100452104763



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
pancreas1.23e-2412
viscus2.31e-1819
body cavity1.42e-0837
body cavity or lining1.42e-0837
body cavity precursor2.66e-0838
anatomical cavity4.82e-0839


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0185483
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.10.736185
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.12.29001
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.11.7574
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.0851423
MA0056.10
MA0057.10.562607
MA0058.10.50032
MA0059.10.513699
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.11.71065
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.880704
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.148348
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.10.440484
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.14.092
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.361633
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.8026
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.157686
MA0146.10.21827
MA0147.10.378658
MA0148.10.621195
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.22.75243
MA0138.20.861035
MA0002.20.299191
MA0137.20.479301
MA0104.20.315156
MA0047.20.75686
MA0112.20.47695
MA0065.20.158101
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.587595
MA0155.10.173445
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.11.01146
MA0160.10.624415
MA0161.10
MA0162.10.245828
MA0163.10.230013
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.20.967156
MA0102.21.79669
MA0258.10.91616
MA0259.10.366802
MA0442.10