MCL coexpression mm9:1122
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr13:85428687..85428741,- | p2@Rasa1 |
| Mm9::chr16:22009544..22009616,+ | p1@Senp2 |
| Mm9::chr1:157820335..157820389,- | p2@Cep350 |
| Mm9::chr1:6204708..6204764,+ | p1@Rb1cc1 |
| Mm9::chr1:84835897..84835966,- | p1@Trip12 |
| Mm9::chr2:173485023..173485053,- | p1@Ppp4r1l-ps |
| Mm9::chr4:132478402..132478459,- | p1@Fam76a |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0043066 | negative regulation of apoptosis | 0.0245418935033708 |
| GO:0043069 | negative regulation of programmed cell death | 0.0245418935033708 |
| GO:0016926 | protein desumoylation | 0.0245418935033708 |
| GO:0045793 | positive regulation of cell size | 0.0404766219854952 |
| GO:0043687 | post-translational protein modification | 0.0404766219854952 |
| GO:0006464 | protein modification process | 0.045608620385925 |
| GO:0043412 | biopolymer modification | 0.045608620385925 |
| GO:0042981 | regulation of apoptosis | 0.045608620385925 |
| GO:0043067 | regulation of programmed cell death | 0.045608620385925 |
| GO:0006512 | ubiquitin cycle | 0.045608620385925 |
| GO:0009887 | organ morphogenesis | 0.045608620385925 |
| GO:0001889 | liver development | 0.045608620385925 |
| GO:0043524 | negative regulation of neuron apoptosis | 0.045608620385925 |
| GO:0001934 | positive regulation of protein amino acid phosphorylation | 0.045608620385925 |
| GO:0033240 | positive regulation of amine metabolic process | 0.045608620385925 |
| GO:0045764 | positive regulation of amino acid metabolic process | 0.045608620385925 |
| GO:0006915 | apoptosis | 0.045608620385925 |
| GO:0001570 | vasculogenesis | 0.045608620385925 |
| GO:0012501 | programmed cell death | 0.045608620385925 |
| GO:0008219 | cell death | 0.045608620385925 |
| GO:0016265 | death | 0.045608620385925 |
| GO:0001726 | ruffle | 0.045608620385925 |
| GO:0043523 | regulation of neuron apoptosis | 0.045608620385925 |
| GO:0051402 | neuron apoptosis | 0.045608620385925 |
| GO:0007254 | JNK cascade | 0.045608620385925 |
| GO:0031098 | stress-activated protein kinase signaling pathway | 0.045608620385925 |
| GO:0051028 | mRNA transport | 0.045608620385925 |
| GO:0044267 | cellular protein metabolic process | 0.045608620385925 |
| GO:0044260 | cellular macromolecule metabolic process | 0.045608620385925 |
| GO:0050658 | RNA transport | 0.045608620385925 |
| GO:0051236 | establishment of RNA localization | 0.045608620385925 |
| GO:0050657 | nucleic acid transport | 0.045608620385925 |
| GO:0006403 | RNA localization | 0.045608620385925 |
| GO:0005643 | nuclear pore | 0.045608620385925 |
| GO:0048523 | negative regulation of cellular process | 0.045608620385925 |
| GO:0033238 | regulation of amine metabolic process | 0.045608620385925 |
| GO:0001932 | regulation of protein amino acid phosphorylation | 0.045608620385925 |
| GO:0006521 | regulation of amino acid metabolic process | 0.045608620385925 |
| GO:0019538 | protein metabolic process | 0.045608620385925 |
| GO:0065002 | intracellular protein transport across a membrane | 0.045608620385925 |
| GO:0015931 | nucleobase, nucleoside, nucleotide and nucleic acid transport | 0.045608620385925 |
| GO:0042325 | regulation of phosphorylation | 0.045608620385925 |
| GO:0051174 | regulation of phosphorus metabolic process | 0.045608620385925 |
| GO:0046930 | pore complex | 0.045608620385925 |
| GO:0019220 | regulation of phosphate metabolic process | 0.045608620385925 |
| GO:0048519 | negative regulation of biological process | 0.0475471885050719 |
| GO:0044453 | nuclear membrane part | 0.0475471885050719 |
| GO:0031965 | nuclear membrane | 0.0480751614853807 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| adult organism | 1.31e-07 | 51 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 2.21402 |
| MA0004.1 | 0.481116 |
| MA0006.1 | 0.837454 |
| MA0007.1 | 2.04776 |
| MA0009.1 | 0.92425 |
| MA0014.1 | 2.85278 |
| MA0017.1 | 0.337808 |
| MA0019.1 | 0.740036 |
| MA0024.1 | 0.880057 |
| MA0025.1 | 1.15921 |
| MA0027.1 | 2.57545 |
| MA0028.1 | 0.860672 |
| MA0029.1 | 0.858105 |
| MA0030.1 | 0.864739 |
| MA0031.1 | 0.828781 |
| MA0038.1 | 0.62758 |
| MA0040.1 | 0.936879 |
| MA0041.1 | 0.404721 |
| MA0042.1 | 0.391504 |
| MA0043.1 | 1.02178 |
| MA0046.1 | 0.960497 |
| MA0048.1 | 0.801219 |
| MA0050.1 | 0.520357 |
| MA0051.1 | 0.636645 |
| MA0052.1 | 0.945011 |
| MA0055.1 | 1.0092 |
| MA0056.1 | 0 |
| MA0057.1 | 0.756125 |
| MA0058.1 | 0.384683 |
| MA0059.1 | 0.397033 |
| MA0060.1 | 0.232592 |
| MA0061.1 | 0.724575 |
| MA0063.1 | 0 |
| MA0066.1 | 1.49567 |
| MA0067.1 | 1.27078 |
| MA0068.1 | 0.771749 |
| MA0069.1 | 0.945354 |
| MA0070.1 | 0.93557 |
| MA0071.1 | 0.519509 |
| MA0072.1 | 0.927016 |
| MA0073.1 | 1.85276 |
| MA0074.1 | 0.580087 |
| MA0076.1 | 0.938908 |
| MA0077.1 | 0.905143 |
| MA0078.1 | 0.670113 |
| MA0081.1 | 0.420276 |
| MA0083.1 | 1.02098 |
| MA0084.1 | 1.59945 |
| MA0087.1 | 0.977537 |
| MA0088.1 | 0.598004 |
| MA0089.1 | 0 |
| MA0090.1 | 1.1347 |
| MA0091.1 | 0.494398 |
| MA0092.1 | 0.446857 |
| MA0093.1 | 0.329976 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.568369 |
| MA0101.1 | 0.406019 |
| MA0103.1 | 0.348572 |
| MA0105.1 | 0.9471 |
| MA0106.1 | 0.677988 |
| MA0107.1 | 0.342432 |
| MA0108.2 | 0.763162 |
| MA0109.1 | 0 |
| MA0111.1 | 0.460823 |
| MA0113.1 | 0.649407 |
| MA0114.1 | 0.259463 |
| MA0115.1 | 1.0246 |
| MA0116.1 | 0.311187 |
| MA0117.1 | 0.992087 |
| MA0119.1 | 0.40661 |
| MA0122.1 | 1.01209 |
| MA0124.1 | 1.21735 |
| MA0125.1 | 1.14291 |
| MA0130.1 | 0 |
| MA0131.1 | 0.735438 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.05845 |
| MA0136.1 | 0.600242 |
| MA0139.1 | 1.10833 |
| MA0140.1 | 0.568252 |
| MA0141.1 | 0.964041 |
| MA0142.1 | 0.814115 |
| MA0143.1 | 0.665982 |
| MA0144.1 | 0.72625 |
| MA0145.1 | 0.304732 |
| MA0146.1 | 0.792204 |
| MA0147.1 | 0.274511 |
| MA0148.1 | 0.49752 |
| MA0149.1 | 0.411562 |
| MA0062.2 | 0.967192 |
| MA0035.2 | 0.573016 |
| MA0039.2 | 3.41853 |
| MA0138.2 | 0.727395 |
| MA0002.2 | 0.205289 |
| MA0137.2 | 0.365364 |
| MA0104.2 | 0.218974 |
| MA0047.2 | 0.626803 |
| MA0112.2 | 1.5617 |
| MA0065.2 | 0.305574 |
| MA0150.1 | 0.465855 |
| MA0151.1 | 0 |
| MA0152.1 | 0.626912 |
| MA0153.1 | 1.07519 |
| MA0154.1 | 0.126143 |
| MA0155.1 | 0.687925 |
| MA0156.1 | 0.936991 |
| MA0157.1 | 0.781683 |
| MA0158.1 | 0 |
| MA0159.1 | 0.284457 |
| MA0160.1 | 0.50056 |
| MA0161.1 | 0 |
| MA0162.1 | 5.32313 |
| MA0163.1 | 1.20194 |
| MA0164.1 | 0.600609 |
| MA0080.2 | 0.343316 |
| MA0018.2 | 1.48306 |
| MA0099.2 | 0.721008 |
| MA0079.2 | 10.4659 |
| MA0102.2 | 1.65195 |
| MA0258.1 | 0.688848 |
| MA0259.1 | 0.26402 |
| MA0442.1 | 0 |
