EntrezGene:5978
From FANTOM5_SSTAR
| Symbol: | REST | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Description: | RE1-silencing transcription factor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Synonyms: | NRSF, XBR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Species: | Human (Homo sapiens) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Xrefs: |
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| Associated motifs: |  JASPAR motif:MA0138.2
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| Transcripton Factor?: | Yes |
TSS regions
| Hg19::chr4:57774018..57774040,+ | p3@REST |
| Hg19::chr4:57774042..57774114,+ | p1@REST |
| Hg19::chr4:57774274..57774299,+ | p8@REST |
| Hg19::chr4:57774626..57774651,+ | p9@REST |
| Hg19::chr4:57774884..57774924,+ | p4@REST |
| Hg19::chr4:57775059..57775139,+ | p2@REST |
| TSS peak ID | Short_description |
|---|
View on UCSC genome browser
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TSS expression
| Sample | p1@REST | p2@REST | p3@REST | p4@REST |
|---|
- Click each plot point to find sample in table
ENCODE TF ChIP-seq peak enrichment analysis Analyst: Erik Arner <br>Summary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><br><br>link to source dataset.<br>data
(#promoters = Number of promoters in the coexpression cluster that have ChIP signal of the TF)
| Coexpression cluster | #promoters | Enrichment | p-value | q-value |
|---|
Coexpression cluster | #promoters | Enrichment | p-value | q-value |
|---|---|---|---|---|
| C699-medulloblastoma-Lens-neuroblastoma-Ciliary-eye-small-cerebellum | 7 | 5.63e+0 | 6.32e-5 | 1.03e-3 |
| C1368-neuroblastoma-rectum-small-colon-locus-duodenum-temporal | 5 | 8.04e+0 | 6.55e-5 | 1.06e-3 |
| C1405-smallcell-pineal-small-occipital-somatostatinoma-medial-amygdala | 5 | 8.04e+0 | 6.55e-5 | 1.06e-3 |
| C1430-neuroectodermal-aorta-Hepatic-Adipocyte-Osteoblast-normal-penis | 5 | 8.04e+0 | 6.55e-5 | 1.06e-3 |
| C1435-Renal-lung-retina-Mesenchymal-placenta-Hepatic-uterus | 5 | 8.04e+0 | 6.55e-5 | 1.06e-3 |
| C1460-neuroectodermal-amygdala-neuroblastoma-medial-frontal-non-occipital | 5 | 8.04e+0 | 6.55e-5 | 1.06e-3 |
| C1529-mature-Synoviocyte-skin-acute-breast-lymphoma-aorta | 5 | 8.04e+0 | 6.55e-5 | 1.06e-3 |
| C613-CD4-CD19-CD8-Natural-CD14-immature-Peripheral | 6 | 4.14e+0 | 1.78e-3 | 1.09e-2 |
| C833-pineal-parietal-occipital-temporal-duodenum-cerebellum-brain | 5 | 4.83e+0 | 1.92e-3 | 1.13e-2 |
| C884-Mesenchymal-Alveolar-Smooth-Renal-Pericytes-Fibroblast-Hepatic | 7 | 7.51e+0 | 3.82e-6 | 1.25e-4 |
Details<b>Summary:</b>It includes sequences from the international sequence collaboration, Swiss-Prot, and RefSeq. The RefSeq subset of this file is also available as gene2refseq.<br><br>links to source dataset.<br>human <br>mouse
| GeneID: | 5978 |
|---|---|
| LocusTag: | - |
| chromosome: | 4 |
| map location: | 4q12 |
| type of gene: | protein-coding |
| Symbol from nomenclature authority: | REST |
| Full name from nomenclature authority: | RE1-silencing transcription factor |
| Nomenclature status: | O |
| Other designations: | neural-restrictive silencer factor, neuron restrictive silencer factor, repressor binding to the X2 box, neural-restrictive silencer factor;;neuron restrictive silencer factor;;repressor binding to the X2 box |
| Modification date: | 08.01.2012 |
