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CL:0000552

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Name:orthochromatic erythroblast
Namespace:FANTOM
Definition:"The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." [ISBN:0721601464]
Xrefs:
links:
FMA:84646
Synonyms: "acidophilic erythroblast" EXACT [ISBN:0721601464]
"eosinophilic erythroblast" EXACT [ISBN:0721601464]
"late erythoblast" EXACT []
"orthochromatic normoblast" EXACT [ISBN:0721601464]
"pyknotic eto enrythroblast" EXACT [ISBN:0721601464]


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000765(erythroblast)
develops_from:CL:0000550(polychromatophilic erythroblast)



Children


develops from:CL:0000558 (reticulocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.




Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000552 (orthochromatic erythroblast), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data