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UBERON:0002514

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Name:intramembranous bone
Definition:"Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [GO:0001957, Wikipedia:Intramembranous_ossification]
Xrefs:
links:

AEO:0000085
EHDAA2:0003085

ZFA:0001635
Synonyms: "membrane bone" RELATED [AEO:0000085]
Alt_id: UBERON:MA_0002837-ZFA_0001635

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0001474(bone element)
develops_from:UBERON:0003104(mesenchyme)



Children

is a:UBERON:0002244 (premaxilla),UBERON:0002397 (maxilla)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

  • 10813-111B3 (normal embryonic palatal mesenchymal cell line:HEPM)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002514 (intramembranous bone), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
5.42e-195FFCP PHASE1:Hg19::chr17:54893192..54893195,-#_a7077f2e3b9fe96fb7dda1d7da71929fp14@C17orf67
5.42e-195FFCP PHASE2:Hg19::chr17:54893192..54893195,-#_a7077f2e3b9fe96fb7dda1d7da71929fp14@C17orf67
9.37e-99FFCP PHASE1:Hg19::chr17:54893269..54893278,-#_eb31da55f19578a6763d1bcaa4f394bep11@C17orf67
9.37e-99FFCP PHASE2:Hg19::chr17:54893213..54893220,-#_eb31da55f19578a6763d1bcaa4f394bep12@C17orf67
9.37e-99FFCP PHASE2:Hg19::chr8:57353655..57353662,-#_eb31da55f19578a6763d1bcaa4f394bep@chr8:57353655..57353662, -
9.37e-99FFCP PHASE1:Hg19::chr17:54893292..54893300,-#_eb31da55f19578a6763d1bcaa4f394bep13@C17orf67
9.37e-99FFCP PHASE2:Hg19::chr17:54893269..54893278,-#_eb31da55f19578a6763d1bcaa4f394bep11@C17orf67
9.37e-99FFCP PHASE2:Hg19::chr17:54893292..54893300,-#_eb31da55f19578a6763d1bcaa4f394bep13@C17orf67
9.37e-99FFCP PHASE1:Hg19::chr8:57353655..57353662,-#_eb31da55f19578a6763d1bcaa4f394bep@chr8:57353655..57353662, -
9.37e-99FFCP PHASE1:Hg19::chr17:54893213..54893220,-#_eb31da55f19578a6763d1bcaa4f394bep12@C17orf67
2.39e-66FFCP PHASE2:Hg19::chr5:75912402..75912418,-#_a96ea19f65b95520c848592d8c3bb6f1p@chr5:75912402..75912418, -
2.39e-66FFCP PHASE1:Hg19::chr4:151503647..151503656,+#_a96ea19f65b95520c848592d8c3bb6f1p14@MAB21L2
2.39e-66FFCP PHASE2:Hg19::chr4:151503647..151503656,+#_a96ea19f65b95520c848592d8c3bb6f1p14@MAB21L2
2.39e-66FFCP PHASE1:Hg19::chr5:75912402..75912418,-#_a96ea19f65b95520c848592d8c3bb6f1p@chr5:75912402..75912418, -
4.66e-66FFCP PHASE1:Hg19::chr4:151505582..151505614,+#_cb493a05078c2cabbd3035b627db98d2p@chr4:151505582..151505614, +
4.66e-66FFCP PHASE2:Hg19::chr4:151505582..151505614,+#_cb493a05078c2cabbd3035b627db98d2p@chr4:151505582..151505614, +
1.46e-50FFCP PHASE2:Hg19::chr3:157823323..157823328,+#_5e73d951729c6885d520ff45ac1009f3p17@RSRC1
1.46e-50FFCP PHASE1:Hg19::chr3:157823323..157823328,+#_5e73d951729c6885d520ff45ac1009f3p17@RSRC1
1.46e-50FFCP PHASE1:Hg19::chr8:57354278..57354286,+#_5e73d951729c6885d520ff45ac1009f3p@chr8:57354278..57354286, +
1.46e-50FFCP PHASE1:Hg19::chr17:54893196..54893207,-#_5e73d951729c6885d520ff45ac1009f3p9@C17orf67
1.46e-50FFCP PHASE2:Hg19::chr8:57354278..57354286,+#_5e73d951729c6885d520ff45ac1009f3p@chr8:57354278..57354286, +
1.46e-50FFCP PHASE2:Hg19::chr17:54893196..54893207,-#_5e73d951729c6885d520ff45ac1009f3p9@C17orf67
2.42e-50FFCP PHASE2:Hg19::chr8:57802672..57802682,-#_5cae14decd4efe8a57e1035f2d35794fp@chr8:57802672..57802682, -
2.42e-50FFCP PHASE1:Hg19::chr8:57802672..57802682,-#_5cae14decd4efe8a57e1035f2d35794fp@chr8:57802672..57802682, -
3.99e-50FFCP PHASE2:Hg19::chr12:85673913..85673919,+#_57cc08dd1bd9389f0404c280c6de9969p7@ALX1
3.99e-50FFCP PHASE1:Hg19::chr12:85673913..85673919,+#_57cc08dd1bd9389f0404c280c6de9969p7@ALX1
3.99e-50FFCP PHASE1:Hg19::chr5:75913767..75913778,-#_57cc08dd1bd9389f0404c280c6de9969p@chr5:75913767..75913778, -
3.99e-50FFCP PHASE1:Hg19::chr17:76930661..76930674,+#_57cc08dd1bd9389f0404c280c6de9969p1@AK123925
3.99e-50FFCP PHASE2:Hg19::chr5:75913767..75913778,-#_57cc08dd1bd9389f0404c280c6de9969p@chr5:75913767..75913778, -
3.99e-50FFCP PHASE2:Hg19::chr17:76930661..76930674,+#_57cc08dd1bd9389f0404c280c6de9969p1@AK123925
6.58e-50FFCP PHASE1:Hg19::chr2:33519090..33519092,+#_89be10955720bd3b74a0855a7353724ep@chr2:33519090..33519092, +
6.58e-50FFCP PHASE2:Hg19::chr13:28961248..28961262,-#_89be10955720bd3b74a0855a7353724ep23@FLT1
6.58e-50FFCP PHASE1:Hg19::chr13:28961248..28961262,-#_89be10955720bd3b74a0855a7353724ep23@FLT1
6.58e-50FFCP PHASE2:Hg19::chr2:33519090..33519092,+#_89be10955720bd3b74a0855a7353724ep@chr2:33519090..33519092, +
6.62e-41FFCP PHASE1:Hg19::chr8:57353666..57353675,-#_cf57feb5c470e4987c159b54e864803ep@chr8:57353666..57353675, -
6.62e-41FFCP PHASE2:Hg19::chr8:57354143..57354152,+#_cf57feb5c470e4987c159b54e864803ep@chr8:57354143..57354152, +
6.62e-41FFCP PHASE2:Hg19::chr8:57353779..57353790,-#_cf57feb5c470e4987c159b54e864803ep@chr8:57353779..57353790, -
6.62e-41FFCP PHASE2:Hg19::chr8:57353666..57353675,-#_cf57feb5c470e4987c159b54e864803ep@chr8:57353666..57353675, -
6.62e-41FFCP PHASE1:Hg19::chr8:57353779..57353790,-#_cf57feb5c470e4987c159b54e864803ep@chr8:57353779..57353790, -
6.62e-41FFCP PHASE1:Hg19::chr8:57354143..57354152,+#_cf57feb5c470e4987c159b54e864803ep@chr8:57354143..57354152, +
1.48e-40FFCP PHASE2:Hg19::chr20:49253452..49253461,-#_db72ca8556297fa2ad8d17684d3beb92p12@FAM65C
1.48e-40FFCP PHASE1:Hg19::chr1:75600308..75600316,+#_db72ca8556297fa2ad8d17684d3beb92p8@LHX8
1.48e-40FFCP PHASE2:Hg19::chr1:6615391..6615401,+#_db72ca8556297fa2ad8d17684d3beb92p2@TAS1R1
1.48e-40FFCP PHASE2:Hg19::chr1:75600308..75600316,+#_db72ca8556297fa2ad8d17684d3beb92p8@LHX8
1.48e-40FFCP PHASE1:Hg19::chr20:49253452..49253461,-#_db72ca8556297fa2ad8d17684d3beb92p12@FAM65C
1.48e-40FFCP PHASE1:Hg19::chr1:6615391..6615401,+#_db72ca8556297fa2ad8d17684d3beb92p2@TAS1R1
2.21e-40FFCP PHASE1:Hg19::chr5:75912831..75912842,-#_a883ebc33d2b51e0ab1ed7266f6bbf0ap@chr5:75912831..75912842, -
2.21e-40FFCP PHASE1:Hg19::chr16:67687543..67687559,-#_a883ebc33d2b51e0ab1ed7266f6bbf0ap@chr16:67687543..67687559, -
2.21e-40FFCP PHASE2:Hg19::chr5:75912831..75912842,-#_a883ebc33d2b51e0ab1ed7266f6bbf0ap@chr5:75912831..75912842, -
2.21e-40FFCP PHASE2:Hg19::chr16:67687543..67687559,-#_a883ebc33d2b51e0ab1ed7266f6bbf0ap@chr16:67687543..67687559, -
3.3e-40FFCP PHASE1:Hg19::chr9:125165007..125165016,+#_7aabaef326eb6fb2acce9bcf9b655edep@chr9:125165007..125165016, +
3.3e-40FFCP PHASE1:Hg19::chr6:46190219..46190230,-#_7aabaef326eb6fb2acce9bcf9b655edep@chr6:46190219..46190230, -
3.3e-40FFCP PHASE2:Hg19::chr9:125165007..125165016,+#_7aabaef326eb6fb2acce9bcf9b655edep@chr9:125165007..125165016, +
3.3e-40FFCP PHASE2:Hg19::chr6:46190219..46190230,-#_7aabaef326eb6fb2acce9bcf9b655edep@chr6:46190219..46190230, -
1.84e-34FFCP PHASE1:Hg19::chr4:8594472..8594473,+#_18c06f93c83199f42eb02ad962ea0dcfp4@CPZ
1.84e-34FFCP PHASE2:Hg19::chr4:8594472..8594473,+#_18c06f93c83199f42eb02ad962ea0dcfp4@CPZ
1.84e-34FFCP PHASE1:Hg19::chr8:57359557..57359570,-#_18c06f93c83199f42eb02ad962ea0dcfp5@PENK
1.84e-34FFCP PHASE2:Hg19::chr10:15760985..15760992,-#_18c06f93c83199f42eb02ad962ea0dcfp@chr10:15760985..15760992, -
1.84e-34FFCP PHASE1:Hg19::chr10:15760985..15760992,-#_18c06f93c83199f42eb02ad962ea0dcfp@chr10:15760985..15760992, -
1.84e-34FFCP PHASE2:Hg19::chr8:57359557..57359570,-#_18c06f93c83199f42eb02ad962ea0dcfp5@PENK
2.58e-34FFCP PHASE2:Hg19::chr14:61125018..61125037,-#_54143d7fccfeef8ef10ab96783615919p9@SIX1
2.58e-34FFCP PHASE1:Hg19::chr14:61125018..61125037,-#_54143d7fccfeef8ef10ab96783615919p9@SIX1
5.05e-34FFCP PHASE2:Hg19::chr6:134327986..134327991,-#_7e1214622e3b5170151fe231399cbab4p@chr6:134327986..134327991, -
5.05e-34FFCP PHASE1:Hg19::chr6:134327986..134327991,-#_7e1214622e3b5170151fe231399cbab4p@chr6:134327986..134327991, -
7.06e-34FFCP PHASE1:Hg19::chr8:57353676..57353688,-#_bb4754e90212e9fee78c437100d49853p@chr8:57353676..57353688, -
7.06e-34FFCP PHASE2:Hg19::chr13:58291223..58291226,+#_bb4754e90212e9fee78c437100d49853p@chr13:58291223..58291226, +
7.06e-34FFCP PHASE1:Hg19::chr13:58291223..58291226,+#_bb4754e90212e9fee78c437100d49853p@chr13:58291223..58291226, +
7.06e-34FFCP PHASE2:Hg19::chr8:57353676..57353688,-#_bb4754e90212e9fee78c437100d49853p@chr8:57353676..57353688, -
9.85e-34FFCP PHASE1:Hg19::chr5:127873659..127873667,-#_0d3fd292adef110f2997daa97721291cp12@FBN2
9.85e-34FFCP PHASE1:Hg19::chr5:19721484..19721507,-#_0d3fd292adef110f2997daa97721291cp@chr5:19721484..19721507, -
9.85e-34FFCP PHASE1:Hg19::chrX:133792540..133792551,-#_0d3fd292adef110f2997daa97721291cp4@PLAC1
9.85e-34FFCP PHASE2:Hg19::chr5:127873659..127873667,-#_0d3fd292adef110f2997daa97721291cp12@FBN2
9.85e-34FFCP PHASE2:Hg19::chr5:19721484..19721507,-#_0d3fd292adef110f2997daa97721291cp@chr5:19721484..19721507, -
9.85e-34FFCP PHASE2:Hg19::chrX:133792540..133792551,-#_0d3fd292adef110f2997daa97721291cp4@PLAC1
7.48e-30FFCP PHASE1:Hg19::chr8:57353804..57353821,-#_3c47ba577cef5d986d2c41fa5bbb52ebp@chr8:57353804..57353821, -
7.48e-30FFCP PHASE1:Hg19::chr8:57354360..57354367,+#_3c47ba577cef5d986d2c41fa5bbb52ebp@chr8:57354360..57354367, +
7.48e-30FFCP PHASE2:Hg19::chr8:57353804..57353821,-#_3c47ba577cef5d986d2c41fa5bbb52ebp@chr8:57353804..57353821, -
7.48e-30FFCP PHASE1:Hg19::chr8:57353982..57353991,-#_3c47ba577cef5d986d2c41fa5bbb52ebp@chr8:57353982..57353991, -
7.48e-30FFCP PHASE2:Hg19::chr8:57354360..57354367,+#_3c47ba577cef5d986d2c41fa5bbb52ebp@chr8:57354360..57354367, +
7.48e-30FFCP PHASE2:Hg19::chr8:57353982..57353991,-#_3c47ba577cef5d986d2c41fa5bbb52ebp@chr8:57353982..57353991, -
9.99e-30FFCP PHASE2:Hg19::chr10:15762107..15762114,-#_28f8408f4e0357dce981f10d46855b13p10@ITGA8
9.99e-30FFCP PHASE1:Hg19::chr10:15762107..15762114,-#_28f8408f4e0357dce981f10d46855b13p10@ITGA8
9.99e-30FFCP PHASE1:Hg19::chr3:157824322..157824334,-#_28f8408f4e0357dce981f10d46855b13p7@SHOX2
9.99e-30FFCP PHASE2:Hg19::chr3:157824322..157824334,-#_28f8408f4e0357dce981f10d46855b13p7@SHOX2
1.33e-29FFCP PHASE2:Hg19::chr22:28193943..28193956,-#_b131ee736fd685a5a6db86f215c89691p@chr22:28193943..28193956, -
1.33e-29FFCP PHASE1:Hg19::chrX:132670143..132670152,-#_b131ee736fd685a5a6db86f215c89691p@chrX:132670143..132670152, -
1.33e-29FFCP PHASE1:Hg19::chr17:79071218..79071221,-#_b131ee736fd685a5a6db86f215c89691p@chr17:79071218..79071221, -
1.33e-29FFCP PHASE1:Hg19::chr22:28193943..28193956,-#_b131ee736fd685a5a6db86f215c89691p@chr22:28193943..28193956, -
1.33e-29FFCP PHASE2:Hg19::chrX:132670143..132670152,-#_b131ee736fd685a5a6db86f215c89691p@chrX:132670143..132670152, -
1.33e-29FFCP PHASE2:Hg19::chr17:79071218..79071221,-#_b131ee736fd685a5a6db86f215c89691p@chr17:79071218..79071221, -
1.78e-29FFCP PHASE1:Hg19::chr1:21904551..21904569,-#_5a9f89c474fd7431a727af9d7b429349p@chr1:21904551..21904569, -
1.78e-29FFCP PHASE2:Hg19::chr1:21904551..21904569,-#_5a9f89c474fd7431a727af9d7b429349p@chr1:21904551..21904569, -
3.16e-29FFCP PHASE2:Hg19::chr8:57359975..57359992,-#_8b92b45f8a21cc658f42e0991c3d0ffap@chr8:57359975..57359992, -
3.16e-29FFCP PHASE1:Hg19::chr14:89044406..89044416,+#_8b92b45f8a21cc658f42e0991c3d0ffap@chr14:89044406..89044416, +
3.16e-29FFCP PHASE1:Hg19::chr1:156470861..156470868,-#_8b92b45f8a21cc658f42e0991c3d0ffap18@MEF2D
3.16e-29FFCP PHASE1:Hg19::chr8:57359975..57359992,-#_8b92b45f8a21cc658f42e0991c3d0ffap@chr8:57359975..57359992, -
3.16e-29FFCP PHASE2:Hg19::chr1:156470861..156470868,-#_8b92b45f8a21cc658f42e0991c3d0ffap18@MEF2D
3.16e-29FFCP PHASE2:Hg19::chr14:89044406..89044416,+#_8b92b45f8a21cc658f42e0991c3d0ffap@chr14:89044406..89044416, +
4.2e-29FFCP PHASE2:Hg19::chr4:151503350..151503358,+#_04f4da55b4c4ab820c86fe2811c01216p11@MAB21L2
4.2e-29FFCP PHASE1:Hg19::chr1:6615468..6615485,+#_04f4da55b4c4ab820c86fe2811c01216p1@TAS1R1