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MCL coexpression mm9:850

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Phase1 CAGE Peaks

 Short description
Mm9::chr5:77778509..77778520,-p@chr5:77778509..77778520
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Mm9::chr5:77780274..77780292,-p@chr5:77780274..77780292
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Mm9::chr5:77780308..77780326,-p@chr5:77780308..77780326
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Mm9::chr5:77780313..77780353,+p@chr5:77780313..77780353
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Mm9::chr5:77780374..77780389,-p@chr5:77780374..77780389
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Mm9::chr5:77784612..77784627,-p@chr5:77784612..77784627
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Mm9::chr5:77784669..77784700,-p@chr5:77784669..77784700
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Mm9::chr5:77837059..77837076,-p1@Igfbp7
Mm9::chr5:91503637..91503655,+p1@Ereg


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045740positive regulation of DNA replication0.00685564020990441
GO:0045741positive regulation of epidermal growth factor receptor activity0.00685564020990441
GO:0045840positive regulation of mitosis0.00685564020990441
GO:0048661positive regulation of smooth muscle cell proliferation0.00685564020990441
GO:0048660regulation of smooth muscle cell proliferation0.00685564020990441
GO:0051054positive regulation of DNA metabolic process0.00685564020990441
GO:0007176regulation of epidermal growth factor receptor activity0.00685564020990441
GO:0045742positive regulation of epidermal growth factor receptor signaling pathway0.00799802779350924
GO:0048659smooth muscle cell proliferation0.00872464315354631
GO:0045410positive regulation of interleukin-6 biosynthetic process0.00872464315354631
GO:0042058regulation of epidermal growth factor receptor signaling pathway0.00872464315354631
GO:0005154epidermal growth factor receptor binding0.00933026551260013
GO:0045408regulation of interleukin-6 biosynthetic process0.00999589135654227
GO:0045088regulation of innate immune response0.00999589135654227
GO:0042226interleukin-6 biosynthetic process0.00999589135654227
GO:0045089positive regulation of innate immune response0.00999589135654227
GO:0006275regulation of DNA replication0.0101005577041794
GO:0007173epidermal growth factor receptor signaling pathway0.0101005577041794
GO:0045787positive regulation of progression through cell cycle0.0101005577041794
GO:0033002muscle cell proliferation0.010394872450425
GO:0032635interleukin-6 production0.0121834641934604
GO:0001819positive regulation of cytokine production0.0135284492854635
GO:0051052regulation of DNA metabolic process0.0135284492854635
GO:0005520insulin-like growth factor binding0.0135284492854635
GO:0045937positive regulation of phosphate metabolic process0.0135284492854635
GO:0042327positive regulation of phosphorylation0.0135284492854635
GO:0007088regulation of mitosis0.0159859761569069
GO:0001817regulation of cytokine production0.0171264229806767
GO:0042108positive regulation of cytokine biosynthetic process0.0176372799740115
GO:0009653anatomical structure morphogenesis0.01794974130003
GO:0045727positive regulation of translation0.0206197149518883
GO:0031328positive regulation of cellular biosynthetic process0.0214717333848699
GO:0019221cytokine and chemokine mediated signaling pathway0.0216168201433377
GO:0006261DNA-dependent DNA replication0.0216168201433377
GO:0019838growth factor binding0.0221887454538825
GO:0042035regulation of cytokine biosynthetic process0.0221887454538825
GO:0009891positive regulation of biosynthetic process0.0223625742343424
GO:0042325regulation of phosphorylation0.0223625742343424
GO:0051174regulation of phosphorus metabolic process0.0223625742343424
GO:0019220regulation of phosphate metabolic process0.0223625742343424
GO:0046982protein heterodimerization activity0.0226566428817888
GO:0042089cytokine biosynthetic process0.0226566428817888
GO:0042107cytokine metabolic process0.0226566428817888
GO:0009967positive regulation of signal transduction0.0235910456148225
GO:0051247positive regulation of protein metabolic process0.0251918946131021
GO:0001558regulation of cell growth0.0281075483487805
GO:0045087innate immune response0.0302198657704283
GO:0016049cell growth0.0305358863514335
GO:0050778positive regulation of immune response0.0305358863514335
GO:0002684positive regulation of immune system process0.0305358863514335
GO:0001816cytokine production0.0305358863514335
GO:0048856anatomical structure development0.0305358863514335
GO:0008361regulation of cell size0.0322027952423242
GO:0050776regulation of immune response0.0327664823161875
GO:0002682regulation of immune system process0.0327664823161875
GO:0051240positive regulation of multicellular organismal process0.0330112176730036
GO:0008285negative regulation of cell proliferation0.0330112176730036
GO:0006417regulation of translation0.0358619549827318
GO:0006260DNA replication0.0358619549827318
GO:0001525angiogenesis0.0358619549827318
GO:0031326regulation of cellular biosynthetic process0.0363152168251283
GO:0040008regulation of growth0.0376816538365442
GO:0008083growth factor activity0.0376816538365442
GO:0009889regulation of biosynthetic process0.0385801828165491
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.0399384507060411
GO:0007067mitosis0.040165868369942
GO:0000087M phase of mitotic cell cycle0.040165868369942
GO:0048514blood vessel morphogenesis0.0404817835179124
GO:0008284positive regulation of cell proliferation0.0404817835179124
GO:0000074regulation of progression through cell cycle0.0404817835179124
GO:0048646anatomical structure formation0.0416962136761355
GO:0046983protein dimerization activity0.0437553539093223
GO:0001568blood vessel development0.0442396693255351
GO:0001944vasculature development0.0442831293334266
GO:0032502developmental process0.0459248752799093
GO:0000278mitotic cell cycle0.0468621075906306
GO:0051246regulation of protein metabolic process0.0470783212135285
GO:0000279M phase0.0470783212135285



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
trunk3.28e-1090
subdivision of trunk4.93e-1066
trunk region element1.21e-0879
splanchnic layer of lateral plate mesoderm1.30e-0733
abdomen element3.75e-0749
abdominal segment element3.75e-0749
abdominal segment of trunk3.75e-0749
abdomen3.75e-0749
compound organ5.60e-0743


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.170768
MA0004.10.394951
MA0006.11.24699
MA0007.10.38073
MA0009.11.92363
MA0014.10.248772
MA0017.10.26239
MA0019.11.551
MA0024.10.779446
MA0025.11.05446
MA0027.12.46647
MA0028.10.24786
MA0029.10.757957
MA0030.10.764448
MA0031.10.729293
MA0038.10.534262
MA0040.10.835181
MA0041.10.323687
MA0042.10.311486
MA0043.10.918718
MA0046.10.858391
MA0048.10.281053
MA0050.10.431976
MA0051.10.542972
MA0052.10.84317
MA0055.10.424109
MA0056.10
MA0057.10.0745664
MA0058.10.305206
MA0059.10.316585
MA0060.10.169058
MA0061.10.194456
MA0063.10
MA0066.10.523573
MA0067.11.16502
MA0068.10.077274
MA0069.10.843506
MA0070.10.833895
MA0071.11.10147
MA0072.10.825495
MA0073.13.85717e-05
MA0074.11.22546
MA0076.10.279739
MA0077.10.804033
MA0078.11.40897
MA0081.10.338098
MA0083.10.917931
MA0084.11.49188
MA0087.10.87515
MA0088.10.728131
MA0089.10
MA0090.10.362551
MA0091.10.407455
MA0092.10.95209
MA0093.10.2553
MA0095.10
MA0098.10
MA0100.10.477594
MA0101.10.324888
MA0103.10.272167
MA0105.10.109964
MA0106.10.582805
MA0107.10.266586
MA0108.20.665343
MA0109.10
MA0111.10.375908
MA0113.10.555251
MA0114.10.19245
MA0115.10.921497
MA0116.10.238371
MA0117.10.88947
MA0119.10.325434
MA0122.10.909168
MA0124.11.11203
MA0125.11.03833
MA0130.10
MA0131.10.638414
MA0132.10
MA0133.10
MA0135.10.954884
MA0136.10.508047
MA0139.10.441109
MA0140.10.477483
MA0141.13.98325
MA0142.11.70108
MA0143.11.40057
MA0144.10.195095
MA0145.10.442138
MA0146.10.0548413
MA0147.10.205697
MA0148.10.410398
MA0149.14.29227
MA0062.20.365726
MA0035.20.482026
MA0039.20.0156581
MA0138.20.630612
MA0002.20.145685
MA0137.20.287486
MA0104.20.157347
MA0047.20.533516
MA0112.20.0543294
MA0065.20.0545595
MA0150.10.380623
MA0151.10
MA0152.10.53362
MA0153.10.971406
MA0154.10.982083
MA0155.10.226288
MA0156.10.278949
MA0157.10.683365
MA0158.10
MA0159.10.614411
MA0160.10.413266
MA0161.10
MA0162.10.0143037
MA0163.10.0124565
MA0164.10.508398
MA0080.20.267388
MA0018.20.51781
MA0099.20.624421
MA0079.20.0340753
MA0102.21.5442
MA0258.10.533988
MA0259.10.196451
MA0442.10
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