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MCL coexpression mm9:311

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:30549364..30549374,-p@chr11:30549364..30549374
-
Mm9::chr11:30549375..30549413,-p1@Acyp2
Mm9::chr11:30549417..30549445,-p2@Acyp2
Mm9::chr15:97938965..97939006,+p1@Pfkm
Mm9::chr17:24769553..24769577,-p1@Tsc2
Mm9::chr17:72131974..72132061,+p@chr17:72131974..72132061
+
Mm9::chr1:183950388..183950422,-p2@Enah
Mm9::chr2:71205594..71205618,-p1@Slc25a12
Mm9::chr4:115457601..115457657,+p1@Atpaf1
Mm9::chr4:122878659..122878674,+p3@Nt5c1a
Mm9::chr4:151235807..151235870,-p1@Camta1
Mm9::chr5:111239099..111239132,-p2@Ulk1
Mm9::chr5:35399499..35399544,+p1@Dok7
Mm9::chr5:74038959..74038993,-p1@Sgcb
Mm9::chr5:89363237..89363264,+p6@Slc4a4
Mm9::chr6:127059535..127059587,-p1@9630033F20Rik
Mm9::chr7:112730112..112730128,-p4@Apbb1
Mm9::chr7:96780993..96781002,+p12@Me3
Mm9::chr7:96781009..96781052,+p4@Me3
Mm9::chr8:107800283..107800326,+p2@Nol3
Mm9::chr8:107800338..107800382,+p1@Nol3
Mm9::chr8:13287814..13287856,-p1@Dcun1d2
Mm9::chr8:7002766..7002788,-p@chr8:7002766..7002788
-
Mm9::chr8:75095912..75095923,+p3@Tmem38a
Mm9::chr8:75095968..75096013,+p2@Tmem38a
Mm9::chr9:122714642..122714698,+p1@D9Ertd402e


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0032990cell part morphogenesis0.0191122493797354
GO:0048858cell projection morphogenesis0.0191122493797354
GO:0030030cell projection organization and biogenesis0.0191122493797354
GO:0045792negative regulation of cell size0.0191277037517963
GO:0043112receptor metabolic process0.021094805142216
GO:0016528sarcoplasm0.021094805142216
GO:0007409axonogenesis0.021094805142216
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.021094805142216
GO:0048667neuron morphogenesis during differentiation0.021094805142216
GO:0048812neurite morphogenesis0.021094805142216
GO:0000904cellular morphogenesis during differentiation0.021094805142216
GO:0001843neural tube closure0.021094805142216
GO:0031175neurite development0.021094805142216
GO:0014020primary neural tube formation0.021094805142216
GO:0032989cellular structure morphogenesis0.021094805142216
GO:0000902cell morphogenesis0.021094805142216
GO:0021933radial glia guided migration of granule cell0.021094805142216
GO:0050757thymidylate synthase biosynthetic process0.021094805142216
GO:0008510sodium:bicarbonate symporter activity0.021094805142216
GO:0050760negative regulation of thymidylate synthase biosynthetic process0.021094805142216
GO:0051386regulation of nerve growth factor receptor signaling pathway0.021094805142216
GO:0050758regulation of thymidylate synthase biosynthetic process0.021094805142216
GO:0014067negative regulation of phosphoinositide 3-kinase cascade0.021094805142216
GO:0048666neuron development0.0246203393221278
GO:0001841neural tube formation0.0246703249895695
GO:0001839neural plate morphogenesis0.0246703249895695
GO:0001840neural plate development0.0246703249895695
GO:0001838embryonic epithelial tube formation0.0246703249895695
GO:0016044membrane organization and biogenesis0.0246703249895695
GO:0021915neural tube development0.0262137604618714
GO:0021932hindbrain radial glia guided cell migration0.0262137604618714
GO:0043490malate-aspartate shuttle0.0262137604618714
GO:0048670regulation of collateral sprouting0.0262137604618714
GO:0043547positive regulation of GTPase activity0.0262137604618714
GO:0014066regulation of phosphoinositide 3-kinase cascade0.0262137604618714
GO:0003998acylphosphatase activity0.0262137604618714
GO:0048671negative regulation of collateral sprouting0.0262137604618714
GO:0007167enzyme linked receptor protein signaling pathway0.0274931504544667
GO:0016477cell migration0.0284840120622137
GO:0016331morphogenesis of embryonic epithelium0.0284840120622137
GO:0030182neuron differentiation0.0285935180172963
GO:0007411axon guidance0.0290837250523788
GO:0007399nervous system development0.0290837250523788
GO:0014065phosphoinositide 3-kinase cascade0.0290837250523788
GO:00059456-phosphofructokinase complex0.0290837250523788
GO:0048668collateral sprouting0.0290837250523788
GO:0035035histone acetyltransferase binding0.0290837250523788
GO:0045749negative regulation of S phase of mitotic cell cycle0.0290837250523788
GO:0004473malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity0.0290837250523788
GO:0021535cell migration in hindbrain0.0290837250523788
GO:0048699generation of neurons0.0307620993761674
GO:0048468cell development0.0307620993761674
GO:0006928cell motility0.0307620993761674
GO:0051674localization of cell0.0307620993761674
GO:0031623receptor internalization0.0307620993761674
GO:0004470malic enzyme activity0.0307620993761674
GO:0021684cerebellar granular layer formation0.0307620993761674
GO:0051898negative regulation of protein kinase B signaling cascade0.0307620993761674
GO:0021683cerebellar granular layer morphogenesis0.0307620993761674
GO:00038726-phosphofructokinase activity0.0307620993761674
GO:0015701bicarbonate transport0.0307620993761674
GO:0021681cerebellar granular layer development0.0307620993761674
GO:0021707cerebellar granule cell differentiation0.0307620993761674
GO:0006810transport0.031108361863902
GO:0022008neurogenesis0.0313862890906252
GO:0043062extracellular structure organization and biogenesis0.0313862890906252
GO:0051234establishment of localization0.0327214534708273
GO:0008361regulation of cell size0.0327214534708273
GO:0006108malate metabolic process0.0327214534708273
GO:0051896regulation of protein kinase B signaling cascade0.0327214534708273
GO:0046626regulation of insulin receptor signaling pathway0.0327214534708273
GO:0033261regulation of progression through S phase0.0327214534708273
GO:0045930negative regulation of progression through mitotic cell cycle0.0327214534708273
GO:0007090regulation of S phase of mitotic cell cycle0.0327214534708273
GO:0045786negative regulation of progression through cell cycle0.0372347761055763
GO:0016012sarcoglycan complex0.0372347761055763
GO:0048011nerve growth factor receptor signaling pathway0.0372347761055763
GO:0005522profilin binding0.0372347761055763
GO:0002009morphogenesis of an epithelium0.0399934514235954
GO:0051320S phase0.0408046698041314
GO:0001540beta-amyloid binding0.0408046698041314
GO:0000084S phase of mitotic cell cycle0.0408046698041314
GO:0016011dystroglycan complex0.0408046698041314
GO:0016615malate dehydrogenase activity0.0439637854989046
GO:0050821protein stabilization0.0439637854989046
GO:0050918positive chemotaxis0.0439637854989046
GO:00082535'-nucleotidase activity0.0439637854989046
GO:0005452inorganic anion exchanger activity0.0439637854989046
GO:0008252nucleotidase activity0.0467783819454978
GO:0008443phosphofructokinase activity0.0467783819454978
GO:0031647regulation of protein stability0.0467783819454978
GO:0043648dicarboxylic acid metabolic process0.0467783819454978
GO:0048009insulin-like growth factor receptor signaling pathway0.0467783819454978
GO:0007010cytoskeleton organization and biogenesis0.0473879024900326
GO:0035239tube morphogenesis0.0474167201603526
GO:0051179localization0.0474167201603526
GO:0015380anion exchanger activity0.0493011957011837
GO:0017124SH3 domain binding0.0493011957011837



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
structure with developmental contribution from neural crest2.76e-2292
ectoderm-derived structure6.26e-1795
ectoderm6.26e-1795
presumptive ectoderm6.26e-1795
central nervous system2.79e-1673
nervous system3.81e-1675
regional part of nervous system6.29e-1554
neurectoderm3.72e-1464
neural plate3.72e-1464
presumptive neural plate3.72e-1464
neural tube8.37e-1452
neural rod8.37e-1452
future spinal cord8.37e-1452
neural keel8.37e-1452
ecto-epithelium1.29e-1373
brain1.06e-1147
future brain1.06e-1147
anatomical conduit2.93e-11122
regional part of brain3.39e-1146
tube1.38e-10114
gray matter3.24e-1034
pre-chordal neural plate6.63e-1049
anterior neural tube3.20e-0940
regional part of forebrain1.06e-0839
forebrain1.06e-0839
future forebrain1.06e-0839
brain grey matter2.74e-0829
regional part of telencephalon2.74e-0829
telencephalon2.74e-0829
compound organ1.06e-0743
multi-cellular organism1.10e-07333
primary circulatory organ2.44e-0718
heart2.44e-0718
primitive heart tube2.44e-0718
primary heart field2.44e-0718
anterior lateral plate mesoderm2.44e-0718
heart tube2.44e-0718
heart primordium2.44e-0718
cardiac mesoderm2.44e-0718
cardiogenic plate2.44e-0718
heart rudiment2.44e-0718
tissue2.80e-07349
regional part of cerebral cortex7.72e-0717


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.79043
MA0004.10.111027
MA0006.10.969707
MA0007.10.103069
MA0009.10.425374
MA0014.11.11249
MA0017.10.0466354
MA0019.10.764645
MA0024.10.388875
MA0025.10.630472
MA0027.12.00714
MA0028.10.364782
MA0029.11.72481
MA0030.10.376415
MA0031.10.347586
MA0038.10.199569
MA0040.10.435948
MA0041.10.0735541
MA0042.10.0677776
MA0043.10.5085
MA0046.10.45588
MA0048.10.605593
MA0050.10.414313
MA0051.10.593414
MA0052.10.442788
MA0055.11.66675
MA0056.10
MA0057.10.768043
MA0058.10.0648829
MA0059.10.0701674
MA0060.10.3841
MA0061.10.1011
MA0063.10
MA0066.11.06752
MA0067.10.732677
MA0068.10.115135
MA0069.10.443076
MA0070.10.434849
MA0071.10.132283
MA0072.10.427684
MA0073.10.727877
MA0074.10.16874
MA0076.10.438642
MA0077.10.409496
MA0078.10.228674
MA0081.10.275922
MA0083.10.507806
MA0084.11.04444
MA0087.10.470385
MA0088.10.927229
MA0089.10
MA0090.10.310535
MA0091.10.118208
MA0092.10.0933907
MA0093.10.0438751
MA0095.10
MA0098.10
MA0100.10.943001
MA0101.10.257705
MA0103.10.420839
MA0105.10.361908
MA0106.10.234207
MA0107.10.0483046
MA0108.20.296634
MA0109.10
MA0111.10.3299
MA0113.10.214338
MA0114.10.0229266
MA0115.10.51095
MA0116.10.34339
MA0117.10.48285
MA0119.10.0743976
MA0122.10.500096
MA0124.10.683426
MA0125.10.615761
MA0130.10
MA0131.10.756836
MA0132.10
MA0133.10
MA0135.10.540552
MA0136.10.535598
MA0139.11.10324
MA0140.10.161354
MA0141.11.223
MA0142.10.336004
MA0143.10.22579
MA0144.10.0236754
MA0145.10.234066
MA0146.10.923333
MA0147.10.272153
MA0148.10.119923
MA0149.10.0766295
MA0062.20.0999405
MA0035.20.493344
MA0039.22.22947
MA0138.20.269868
MA0002.20.0570548
MA0137.20.457011
MA0104.20.579417
MA0047.20.199051
MA0112.21.95482
MA0065.20.063724
MA0150.11.13815
MA0151.10
MA0152.10.199123
MA0153.10.55531
MA0154.10.236552
MA0155.10.446252
MA0156.10.0533763
MA0157.10.310784
MA0158.10
MA0159.10.536488
MA0160.10.385618
MA0161.10
MA0162.11.10377
MA0163.10.800051
MA0164.10.181834
MA0080.20.0486268
MA0018.20.551637
MA0099.20.732438
MA0079.20.945154
MA0102.21.09525
MA0258.11.40467
MA0259.10.47498
MA0442.10
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