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Coexpression cluster:C1059

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Full id: C1059_Fibroblast_Adipocyte_Smooth_Chondrocyte_neuroectodermal_Hair_Preadipocyte



Phase1 CAGE Peaks

Hg19::chr19:13050341..13050390,-p@chr19:13050341..13050390
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Hg19::chr19:13051088..13051148,-p@chr19:13051088..13051148
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Hg19::chr19:13051159..13051216,-p@chr19:13051159..13051216
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Hg19::chr19:13051603..13051646,-p@chr19:13051603..13051646
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Hg19::chr19:13054556..13054630,-p3@CALR
Hg19::chr19:13054632..13054644,-p19@CALR
Hg19::chr19:13054647..13054681,-p9@CALR
Hg19::chr19:13054682..13054702,-p14@CALR


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
animal cell1.05e-25679
eukaryotic cell1.05e-25679
somatic cell5.55e-19588
native cell6.38e-14722
embryonic cell1.36e-13250
mesodermal cell2.50e-11121
non-terminally differentiated cell6.33e-10106
fibroblast1.50e-0976
electrically responsive cell1.46e-0861
electrically active cell1.46e-0861
contractile cell1.71e-0859
muscle precursor cell5.81e-0858
myoblast5.81e-0858
multi-potent skeletal muscle stem cell5.81e-0858
muscle cell1.95e-0755
multi fate stem cell6.98e-07427
somatic stem cell8.40e-07433
Uber Anatomy
Ontology termp-valuen
mesenchyme5.04e-10160
entire embryonic mesenchyme5.04e-10160
trunk mesenchyme1.36e-09122
multilaminar epithelium1.95e-0983
epithelial vesicle2.17e-0978
unilaminar epithelium2.48e-09148
epithelial tube7.77e-08117
dense mesenchyme tissue1.00e-0773
somite1.14e-0771
presomitic mesoderm1.14e-0771
presumptive segmental plate1.14e-0771
dermomyotome1.14e-0771
trunk paraxial mesoderm1.14e-0771
paraxial mesoderm2.54e-0772
presumptive paraxial mesoderm2.54e-0772


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00718652
MA0004.10.455723
MA0006.10.300178
MA0007.10.437331
MA0009.10.918715
MA0014.10.0484929
MA0017.10.337901
MA0019.10.602411
MA0024.14.54931
MA0025.11.05265
MA0027.12.5321
MA0028.10.846854
MA0029.10.832916
MA0030.10.821423
MA0031.10.756713
MA0038.10.557409
MA0040.10.838784
MA0041.10.474018
MA0042.11.12605
MA0043.10.919032
MA0046.10.90778
MA0048.10.0955945
MA0050.11.97202
MA0051.10.553205
MA0052.10.842664
MA0055.10.028436
MA0056.10
MA0057.10.632427
MA0058.10.362328
MA0059.10.361075
MA0060.10.190336
MA0061.10.497495
MA0063.10
MA0066.10.557833
MA0067.11.23721
MA0068.10.823119
MA0069.10.903908
MA0070.10.892666
MA0071.11.28975
MA0072.10.888148
MA0073.12.54378
MA0074.10.552456
MA0076.10.985027
MA0077.10.880402
MA0078.10.652193
MA0081.10.361233
MA0083.10.926258
MA0084.11.42483
MA0087.10.885691
MA0088.10.054222
MA0089.10
MA0090.10.391903
MA0091.10.458301
MA0092.10.421159
MA0093.10.303084
MA0095.10
MA0098.10
MA0100.10.571227
MA0101.10.825856
MA0103.10.792149
MA0105.10.586268
MA0106.13.62859
MA0107.10.236528
MA0108.20.753643
MA0109.10
MA0111.10.405141
MA0113.10.614917
MA0114.10.231781
MA0115.11.1606
MA0116.10.239768
MA0117.10.956472
MA0119.10.345493
MA0122.10.982472
MA0124.11.11898
MA0125.11.0347
MA0130.10
MA0131.10.670358
MA0132.10
MA0133.10
MA0135.10.949204
MA0136.10.564434
MA0139.10.155155
MA0140.10.516266
MA0141.10.359385
MA0142.10.724856
MA0143.10.615094
MA0144.10.218541
MA0145.10.0613434
MA0146.12.05336
MA0147.10.243042
MA0148.10.480298
MA0149.10.506665
MA0062.20.485915
MA0035.20.515566
MA0039.20.44475
MA0138.20.653421
MA0002.20.179788
MA0137.20.321796
MA0104.20.189646
MA0047.20.586412
MA0112.20.208783
MA0065.20.844872
MA0150.10.386144
MA0151.10
MA0152.11.29801
MA0153.11.01778
MA0154.10.0799828
MA0155.10.0535085
MA0156.10.865715
MA0157.10.697424
MA0158.10
MA0159.10.682702
MA0160.10.495355
MA0161.10
MA0162.10.0163939
MA0163.10.0517199
MA0164.10.627336
MA0080.20.818924
MA0018.20.599912
MA0099.20.523145
MA0079.20.481761
MA0102.21.46209
MA0258.10.209744
MA0259.10.25092
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ZNF263#1012755.138651023131670.001082531249033560.00763857044239007



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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