MCL coexpression mm9:2198

Phase1 CAGE Peaks

	Short description
Mm9::chr17:28487603..28487626,-	p2@Tead3
Mm9::chr17:46766353..46766368,-	p2@Ptk7
Mm9::chr17:46766369..46766449,-	p1@Ptk7
Mm9::chr7:108542875..108542950,+	p1@Arap1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045198	establishment of epithelial cell polarity	0.0199677618437021
GO:0030859	polarized epithelial cell differentiation	0.0199677618437021
GO:0035089	establishment of apical/basal cell polarity	0.0199677618437021
GO:0045197	establishment and/or maintenance of epithelial cell polarity	0.0199677618437021
GO:0005021	vascular endothelial growth factor receptor activity	0.0199677618437021
GO:0035088	establishment and/or maintenance of apical/basal cell polarity	0.0199677618437021
GO:0001738	morphogenesis of a polarized epithelium	0.0199677618437021
GO:0030010	establishment of cell polarity	0.0206473493878304
GO:0007163	establishment and/or maintenance of cell polarity	0.0338726162623042
GO:0030855	epithelial cell differentiation	0.0452107644855728
GO:0001843	neural tube closure	0.0452107644855728
GO:0014020	primary neural tube formation	0.0452107644855728
GO:0001841	neural tube formation	0.0452107644855728
GO:0001839	neural plate morphogenesis	0.0452107644855728
GO:0001840	neural plate development	0.0452107644855728
GO:0001838	embryonic epithelial tube formation	0.0452107644855728
GO:0004714	transmembrane receptor protein tyrosine kinase activity	0.0458176167496401
GO:0021915	neural tube development	0.0458176167496401
GO:0019199	transmembrane receptor protein kinase activity	0.0463008701603832
GO:0016331	morphogenesis of embryonic epithelium	0.0463008701603832

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
anatomical space	1.90e-08	57
lung	2.72e-07	14
respiratory tube	2.72e-07	14
respiration organ	2.72e-07	14
pair of lungs	2.72e-07	14
lung primordium	2.72e-07	14
lung bud	2.72e-07	14
multi-cellular organism	7.09e-07	333

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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