MCL coexpression mm9:1590

Phase1 CAGE Peaks

	Short description
Mm9::chr11:87607561..87607573,+	p9@Mpo
Mm9::chr11:87689026..87689036,-	p1@Epx
Mm9::chr17:25435334..25435348,+	p1@Prss34
Mm9::chr2:84820615..84820619,+	p1@Prg2
Mm9::chr2:84828351..84828354,+	p1@Prg3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042744	hydrogen peroxide catabolic process	8.27720250147647e-05
GO:0042743	hydrogen peroxide metabolic process	8.27720250147647e-05
GO:0042542	response to hydrogen peroxide	8.27720250147647e-05
GO:0000302	response to reactive oxygen species	0.000165435203631644
GO:0006800	oxygen and reactive oxygen species metabolic process	0.000415176701135355
GO:0004601	peroxidase activity	0.000415176701135355
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	0.000415176701135355
GO:0006118	electron transport	0.000565232096750131
GO:0006979	response to oxidative stress	0.000604669521067218
GO:0006091	generation of precursor metabolites and energy	0.00099363694796803
GO:0020037	heme binding	0.00277640050018335
GO:0046906	tetrapyrrole binding	0.00277640050018335
GO:0005615	extracellular space	0.0043754190341142
GO:0016491	oxidoreductase activity	0.00438512396045173
GO:0044421	extracellular region part	0.00475924687139041
GO:0005506	iron ion binding	0.0143974356699051
GO:0044248	cellular catabolic process	0.0257939663370462
GO:0042221	response to chemical stimulus	0.0261439238351702
GO:0009056	catabolic process	0.0378805281744467

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
abdomen element	5.59e-07	49
abdominal segment element	5.59e-07	49
abdominal segment of trunk	5.59e-07	49
abdomen	5.59e-07	49
hematopoietic system	6.36e-07	45
blood island	6.36e-07	45
spleen	8.04e-07	6
cavity lining	8.04e-07	6
serous membrane	8.04e-07	6
gastrointestinal system mesentery	8.04e-07	6
stomach region	8.04e-07	6
mesentery	8.04e-07	6
gastrointestinal system serosa	8.04e-07	6
mesentery of stomach	8.04e-07	6
gut mesentery	8.04e-07	6
dorsal mesentery	8.04e-07	6
dorsal mesogastrium	8.04e-07	6
peritoneal cavity	8.04e-07	6
spleen primordium	8.04e-07	6

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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