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MCL coexpression mm9:1306

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:87570427..87570431,+p2@Mir142
Mm9::chr1:167615652..167615656,-p@chr1:167615652..167615656
-
Mm9::chr5:86539268..86539274,+p@chr5:86539268..86539274
+
Mm9::chr6:145070282..145070315,+p1@Lrmp
Mm9::chr6:145072003..145072005,+p@chr6:145072003..145072005
+
Mm9::chr6:145111646..145111650,+p@chr6:145111646..145111650
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004839ubiquitin activating enzyme activity0.0157752026064506
GO:0008641small protein activating enzyme activity0.0157752026064506



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
hemopoietic organ8.53e-1429
immune organ8.53e-1429
hematopoietic system2.56e-1245
blood island2.56e-1245
hemolymphoid system8.45e-1248
immune system8.45e-1248
mixed endoderm/mesoderm-derived structure1.12e-1135
foregut2.91e-1180
gland of gut2.19e-1024
thymus3.10e-1023
neck3.10e-1023
respiratory system epithelium3.10e-1023
hemolymphoid system gland3.10e-1023
pharyngeal epithelium3.10e-1023
thymic region3.10e-1023
pharyngeal gland3.10e-1023
entire pharyngeal arch endoderm3.10e-1023
thymus primordium3.10e-1023
early pharyngeal endoderm3.10e-1023
pharynx1.93e-0924
upper respiratory tract1.93e-0924
chordate pharynx1.93e-0924
pharyngeal arch system1.93e-0924
pharyngeal region of foregut1.93e-0924
endocrine system9.99e-0972
organism subdivision7.30e-08150
respiratory system7.99e-0842
endo-epithelium9.02e-0869
respiratory tract1.25e-0741
endocrine gland1.41e-0760
gland1.81e-0765
segment of respiratory tract1.83e-0727
gut epithelium5.17e-0755
lateral plate mesoderm5.88e-0787


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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