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MCL coexpression mm9:690

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:52111412..52111416,+p1@Nepn
Mm9::chr11:96184567..96184569,+p8@Hoxb3
Mm9::chr13:48757894..48757908,+p5@Barx1
Mm9::chr13:48758072..48758117,-p@chr13:48758072..48758117
-
Mm9::chr13:48758276..48758291,+p1@Barx1
Mm9::chr13:48758328..48758335,+p4@Barx1
Mm9::chr13:48758358..48758415,+p2@Barx1
Mm9::chr13:48758431..48758443,+p3@Barx1
Mm9::chr2:62318547..62318556,-p2@Gcg
Mm9::chr3:122393672..122393673,+p@chr3:122393672..122393673
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007267cell-cell signaling0.0416563664909537
GO:0030878thyroid gland development0.0416563664909537
GO:0050796regulation of insulin secretion0.0416563664909537
GO:0005667transcription factor complex0.0416563664909537
GO:0043565sequence-specific DNA binding0.0416563664909537
GO:0030178negative regulation of Wnt receptor signaling pathway0.0416563664909537
GO:0046883regulation of hormone secretion0.0416563664909537
GO:0044451nucleoplasm part0.0416563664909537
GO:0030111regulation of Wnt receptor signaling pathway0.0416563664909537
GO:0030073insulin secretion0.0416563664909537
GO:0005654nucleoplasm0.0416563664909537
GO:0030072peptide hormone secretion0.0427696953751431
GO:0002790peptide secretion0.0427696953751431
GO:0031981nuclear lumen0.0427696953751431
GO:0030855epithelial cell differentiation0.0427696953751431
GO:0015833peptide transport0.0427696953751431
GO:0046879hormone secretion0.0427696953751431
GO:0031974membrane-enclosed lumen0.0427696953751431
GO:0043233organelle lumen0.0427696953751431
GO:0035270endocrine system development0.0459066551200862
GO:0003700transcription factor activity0.0459066551200862
GO:0051046regulation of secretion0.0459066551200862



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
stomach3.55e-1216
food storage organ3.55e-1216
pancreas1.16e-0912
viscus4.50e-0719


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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