MCL coexpression mm9:350

Phase1 CAGE Peaks

	Short description
Mm9::chr11:101755013..101755094,-	p@chr11:101755013..101755094 -
Mm9::chr11:30143050..30143055,-	p@chr11:30143050..30143055 -
Mm9::chr17:10423983..10423987,-	p@chr17:10423983..10423987 -
Mm9::chr17:24781878..24781921,-	p2@Slc9a3r2
Mm9::chr2:179997285..179997300,-	p@chr2:179997285..179997300 -
Mm9::chr5:136019136..136019144,-	p@chr5:136019136..136019144 -
Mm9::chr6:91671712..91671734,+	p@chr6:91671712..91671734 +
Mm9::chr7:80885163..80885219,+	p2@Fam174b
Mm9::chr8:12926192..12926201,+	p14@Mcf2l
Mm9::chr8:12926204..12926218,+	p11@Mcf2l
Mm9::chr8:12926268..12926291,+	p2@Mcf2l
Mm9::chr8:12926299..12926317,+	p4@Mcf2l
Mm9::chr9:48122532..48122588,+	p@chr9:48122532..48122588 +
Mm9::chr9:60713920..60713971,+	p@chr9:60713920..60713971 +
Mm9::chr9:79809768..79809783,-	p11@Filip1
Mm9::chr9:79809790..79809808,-	p7@Filip1
Mm9::chrX:18038392..18038406,-	p3@4930578C19Rik
Mm9::chrX:18038411..18038449,-	p1@4930578C19Rik
Mm9::chrX:18038511..18038528,-	p2@4930578C19Rik
Mm9::chrX:6154428..6154445,+	p6@Shroom4
Mm9::chrX:7258341..7258355,-	p3@Magix
Mm9::chrX:7258356..7258382,-	p2@Magix

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016324	apical plasma membrane	0.0123051114716402
GO:0045177	apical part of cell	0.0152455547678518
GO:0001757	somite specification	0.0384173101686729
GO:0009898	internal side of plasma membrane	0.0384173101686729
GO:0005545	phosphatidylinositol binding	0.0384173101686729
GO:0031941	filamentous actin	0.0384173101686729
GO:0007379	segment specification	0.0384173101686729
GO:0009925	basal plasma membrane	0.0384173101686729
GO:0045178	basal part of cell	0.0384173101686729
GO:0030864	cortical actin cytoskeleton	0.0422474663285222

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
multi-cellular organism	4.02e-10	333
lung	1.34e-07	14
respiratory tube	1.34e-07	14
respiration organ	1.34e-07	14
pair of lungs	1.34e-07	14
lung primordium	1.34e-07	14
lung bud	1.34e-07	14
epithelial bud	1.82e-07	17
anatomical space	6.66e-07	57

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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