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Coexpression cluster:C4167

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Full id: C4167_parietal_temporal_occipital_duodenum_putamen_pituitary_neuroectodermal



Phase1 CAGE Peaks

Hg19::chr2:197791441..197791525,-p1@PGAP1
Hg19::chrX:73439688..73439692,-p@chrX:73439688..73439692
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Hg19::chrX:73513353..73513414,-p1@FTX


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0015798myo-inositol transport0.00294360061226893
GO:0015791polyol transport0.00367950076533615
GO:0006505GPI anchor metabolic process0.0152086031633895
GO:0031227intrinsic to endoplasmic reticulum membrane0.0224449546685506
GO:0030384phosphoinositide metabolic process0.0235488048981514
GO:0006650glycerophospholipid metabolic process0.0247753051532635
GO:0031300intrinsic to organelle membrane0.0319590923617769
GO:0006644phospholipid metabolic process0.0395546332273637
GO:0004518nuclease activity0.0400329683268574
GO:0006643membrane lipid metabolic process0.0400329683268574



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism6.94e-35114
nervous system4.33e-3089
central nervous system9.38e-3081
neural tube1.18e-2856
neural rod1.18e-2856
future spinal cord1.18e-2856
neural keel1.18e-2856
regional part of nervous system6.63e-2753
regional part of brain6.63e-2753
brain1.25e-2568
future brain1.25e-2568
regional part of forebrain4.48e-2441
forebrain4.48e-2441
anterior neural tube4.48e-2441
future forebrain4.48e-2441
brain grey matter4.02e-2034
gray matter4.02e-2034
telencephalon4.49e-2034
neurectoderm3.63e-1986
cerebral hemisphere3.99e-1932
regional part of telencephalon4.33e-1932
neural plate4.68e-1882
presumptive neural plate4.68e-1882
ectoderm-derived structure7.28e-17171
ectoderm7.28e-17171
presumptive ectoderm7.28e-17171
cerebral cortex5.57e-1525
pallium5.57e-1525
regional part of cerebral cortex1.09e-1422
organ system subdivision2.54e-14223
pre-chordal neural plate1.34e-1361
neocortex1.97e-1320
ecto-epithelium1.29e-11104
structure with developmental contribution from neural crest1.30e-09132
basal ganglion6.57e-079
nuclear complex of neuraxis6.57e-079
aggregate regional part of brain6.57e-079
collection of basal ganglia6.57e-079
cerebral subcortex6.57e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.