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Coexpression cluster:C3949

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Full id: C3949_Ewing_Adipocyte_Olfactory_Hair_neurofibroma_Preadipocyte_hepatic



Phase1 CAGE Peaks

Hg19::chr1:230974249..230974267,-p3@C1orf198
Hg19::chr1:230974293..230974314,-p6@C1orf198
Hg19::chr1:230974321..230974342,-p9@C1orf198


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fibroblast8.85e-0776
Uber Anatomy
Ontology termp-valuen
anatomical cluster2.19e-11373
epithelium4.34e-11306
multi-tissue structure7.61e-11342
cell layer1.02e-10309
nervous system1.54e-1089
central nervous system2.43e-1081
organ system subdivision4.33e-09223
neural tube4.91e-0956
neural rod4.91e-0956
future spinal cord4.91e-0956
neural keel4.91e-0956
neural plate1.55e-0882
presumptive neural plate1.55e-0882
neurectoderm1.78e-0886
ectoderm-derived structure2.26e-08171
ectoderm2.26e-08171
presumptive ectoderm2.26e-08171
brain3.19e-0868
future brain3.19e-0868
structure with developmental contribution from neural crest3.45e-08132
regional part of nervous system1.01e-0753
regional part of brain1.01e-0753
brain grey matter1.23e-0734
gray matter1.23e-0734
multi-cellular organism1.31e-07656
ecto-epithelium2.26e-07104
organ part5.18e-07218
tube5.61e-07192
anatomical conduit6.70e-07240
telencephalon7.12e-0734
regional part of telencephalon9.02e-0732


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.