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MCL coexpression mm9:922

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:97011339..97011398,-p1@Tbkbp1
Mm9::chr12:27100064..27100079,-p2@Rnf144a
Mm9::chr16:95680624..95680630,-p@chr16:95680624..95680630
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Mm9::chr16:95680889..95680991,-p1@Erg
Mm9::chr18:38146824..38146828,-p@chr18:38146824..38146828
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Mm9::chr18:38158368..38158425,-p1@Arap3
Mm9::chr18:38159171..38159194,-p@chr18:38159171..38159194
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Mm9::chr6:72254313..72254324,+p8@Sftpb


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0035024negative regulation of Rho protein signal transduction0.0271624509120334
GO:0035021negative regulation of Rac protein signal transduction0.0271624509120334
GO:0008060ARF GTPase activator activity0.0271624509120334
GO:0050828regulation of liquid surface tension0.0271624509120334
GO:0035020regulation of Rac protein signal transduction0.0271624509120334
GO:0051058negative regulation of small GTPase mediated signal transduction0.0271624509120334
GO:0030336negative regulation of cell migration0.0429612841110319
GO:0005100Rho GTPase activator activity0.0429612841110319
GO:0016601Rac protein signal transduction0.0429612841110319
GO:0051271negative regulation of cell motility0.0429612841110319
GO:0007585respiratory gaseous exchange0.0429612841110319
GO:0040013negative regulation of locomotion0.0429612841110319



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
trunk region element4.50e-1179
subdivision of trunk7.56e-1166
trunk1.04e-0990
lung1.85e-0914
respiratory tube1.85e-0914
respiration organ1.85e-0914
pair of lungs1.85e-0914
lung primordium1.85e-0914
lung bud1.85e-0914
epithelial bud3.26e-0817


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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