MCL coexpression mm9:792

Phase1 CAGE Peaks

	Short description
Mm9::chr11:70265407..70265452,+	p1@Med11
Mm9::chr17:26813332..26813333,+	p3@Atp6v0e
Mm9::chr17:26813335..26813346,+	p2@Atp6v0e
Mm9::chr17:26813350..26813411,+	p1@Atp6v0e
Mm9::chr19:5490512..5490525,+	p1@Cfl1 p1@LOC100048522
Mm9::chr3:146162814..146162850,+	p1@Gm13342 p1@Gm15776 p1@Gm4356 p1@Gng5 p1@LOC100048410
Mm9::chr5:124928339..124928393,-	p1@Rilpl2
Mm9::chr6:113328152..113328185,+	p1@Arpc4
Mm9::chr6:136756784..136756866,+	p1@H2afj

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0043234	protein complex	0.00580002165270492
GO:0008154	actin polymerization and/or depolymerization	0.00602443029504808
GO:0032991	macromolecular complex	0.00602443029504808
GO:0044446	intracellular organelle part	0.00776976149973157
GO:0044422	organelle part	0.00776976149973157
GO:0030836	positive regulation of actin filament depolymerization	0.0253074409282662
GO:0001842	neural fold formation	0.0299583719443181
GO:0030036	actin cytoskeleton organization and biogenesis	0.0299583719443181
GO:0030029	actin filament-based process	0.0305337940963763
GO:0015629	actin cytoskeleton	0.036334407086668
GO:0051130	positive regulation of cellular component organization and biogenesis	0.0404586405716512
GO:0015991	ATP hydrolysis coupled proton transport	0.0404586405716512
GO:0005885	Arp2/3 protein complex	0.0404586405716512
GO:0003779	actin binding	0.0404586405716512
GO:0015988	energy coupled proton transport, against electrochemical gradient	0.0404586405716512

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

---

Cell Type

Ontology term	p-value	n
motile cell	3.23e-15	54
connective tissue cell	4.62e-11	46
mesenchymal cell	4.62e-11	46
somatic cell	8.07e-11	118
animal cell	1.83e-09	115
eukaryotic cell	1.83e-09	115
hematopoietic cell	2.64e-07	32
hematopoietic oligopotent progenitor cell	2.64e-07	32
hematopoietic stem cell	2.64e-07	32
angioblastic mesenchymal cell	2.64e-07	32
hematopoietic multipotent progenitor cell	2.64e-07	32
migratory neural crest cell	5.97e-07	10
neuron associated cell	5.97e-07	10
glial cell (sensu Vertebrata)	5.97e-07	10
neuron associated cell (sensu Vertebrata)	5.97e-07	10
glial cell	5.97e-07	10
glioblast	5.97e-07	10
glioblast (sensu Vertebrata)	5.97e-07	10

Uber Anatomy

Ontology term	p-value	n
connective tissue	4.62e-11	46
musculoskeletal system	3.64e-09	32
bone marrow	4.38e-08	16

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}