MCL coexpression mm9:245

Phase1 CAGE Peaks

	Short description
Mm9::chr10:128113787..128113796,-	p@chr10:128113787..128113796 -
Mm9::chr10:46225439..46225441,-	p@chr10:46225439..46225441 -
Mm9::chr10:61422349..61422356,+	p@chr10:61422349..61422356 +
Mm9::chr10:62224425..62224431,+	p@chr10:62224425..62224431 +
Mm9::chr13:118836100..118836109,+	p@chr13:118836100..118836109 +
Mm9::chr14:52473442..52473447,+	p1@Ear6 p1@Ear7
Mm9::chr15:76168002..76168027,+	p1@ENSMUST00000074205
Mm9::chr15:77338698..77338700,+	p1@Apol11a
Mm9::chr15:79164786..79164787,-	p@chr15:79164786..79164787 -
Mm9::chr16:32822173..32822174,+	p@chr16:32822173..32822174 +
Mm9::chr16:58555862..58555865,-	p@chr16:58555862..58555865 -
Mm9::chr17:12285576..12285577,+	p@chr17:12285576..12285577 +
Mm9::chr17:74886567..74886581,+	p1@ENSMUST00000166175
Mm9::chr18:30768709..30768710,-	p@chr18:30768709..30768710 -
Mm9::chr18:66708545..66708551,+	p@chr18:66708545..66708551 +
Mm9::chr1:136005913..136005920,+	p1@Gm8618
Mm9::chr1:192441351..192441352,-	p@chr1:192441351..192441352 -
Mm9::chr1:73400956..73400959,-	p@chr1:73400956..73400959 -
Mm9::chr2:147341716..147341717,+	p@chr2:147341716..147341717 +
Mm9::chr4:105250900..105250907,+	p1@ENSMUST00000121621
Mm9::chr4:105466778..105466786,+	p1@ENSMUST00000119740
Mm9::chr4:134984627..134984636,-	p@chr4:134984627..134984636 -
Mm9::chr5:67844705..67844708,+	p@chr5:67844705..67844708 +
Mm9::chr6:107388309..107388310,-	p@chr6:107388309..107388310 -
Mm9::chr6:13411995..13411996,-	p@chr6:13411995..13411996 -
Mm9::chr7:109189797..109189803,+	p@chr7:109189797..109189803 +
Mm9::chr7:34822489..34822490,-	p1@ENSMUST00000117861
Mm9::chr7:82653484..82653491,-	p@chr7:82653484..82653491 -
Mm9::chr8:119025600..119025605,+	p@chr8:119025600..119025605 +
Mm9::chr8:25929441..25929443,+	p@chr8:25929441..25929443 +
Mm9::chr8:26771946..26771952,-	p@chr8:26771946..26771952 -
Mm9::chr9:59504911..59504929,+	p@chr9:59504911..59504929 +
Mm9::chr9:72022794..72022811,-	p1@Gm7866
Mm9::chrX:134243545..134243548,+	p@chrX:134243545..134243548 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004540	ribonuclease activity	0.0124910973538596
GO:0004518	nuclease activity	0.0145729469128362
GO:0016788	hydrolase activity, acting on ester bonds	0.0439014591208751

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br><br>

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Cell Type

Ontology term	p-value	n
lymphocyte	1.04e-10	13
common lymphoid progenitor	1.04e-10	13
lymphoid lineage restricted progenitor cell	1.50e-09	12
hematopoietic lineage restricted progenitor cell	5.48e-09	25
nucleate cell	1.17e-08	16
T cell	2.60e-08	11
pro-T cell	2.60e-08	11
leukocyte	3.92e-08	17
nongranular leukocyte	3.92e-08	17
hematopoietic cell	6.34e-08	32
hematopoietic oligopotent progenitor cell	6.34e-08	32
hematopoietic stem cell	6.34e-08	32
angioblastic mesenchymal cell	6.34e-08	32
hematopoietic multipotent progenitor cell	6.34e-08	32

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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