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MCL coexpression mm9:1677

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Phase1 CAGE Peaks

 Short description
Mm9::chr15:39491058..39491131,+p1@Rims2
Mm9::chr15:72378118..72378137,-p@chr15:72378118..72378137
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Mm9::chr1:75543215..75543229,+p6@Slc4a3
Mm9::chr4:122878468..122878513,+p4@Nt5c1a
Mm9::chr4:122878746..122878772,+p2@Nt5c1a


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:00082535'-nucleotidase activity0.0242162498772717
GO:0005452inorganic anion exchanger activity0.0242162498772717
GO:0008252nucleotidase activity0.0242162498772717
GO:0015380anion exchanger activity0.0242162498772717
GO:0015106bicarbonate transmembrane transporter activity0.0242162498772717
GO:0015301anion:anion antiporter activity0.0242162498772717
GO:0015108chloride transmembrane transporter activity0.0242162498772717
GO:0017137Rab GTPase binding0.0313776749010759
GO:0017156calcium ion-dependent exocytosis0.0313776749010759
GO:0030073insulin secretion0.0314828234138316
GO:0030072peptide hormone secretion0.0314828234138316
GO:0015103inorganic anion transmembrane transporter activity0.0314828234138316
GO:0002790peptide secretion0.0314828234138316
GO:0015297antiporter activity0.035735271435484
GO:0015833peptide transport0.035735271435484
GO:0046879hormone secretion0.0361407521892148
GO:0006836neurotransmitter transport0.0378365687345399
GO:0017016Ras GTPase binding0.0378365687345399
GO:0031267small GTPase binding0.0378365687345399
GO:0051020GTPase binding0.038755433051013
GO:0019933cAMP-mediated signaling0.0402543445152911
GO:0019935cyclic-nucleotide-mediated signaling0.040339193295129



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
structure with developmental contribution from neural crest3.71e-2392
central nervous system6.97e-1973
nervous system1.48e-1875
regional part of nervous system3.51e-1854
neurectoderm1.35e-1664
neural plate1.35e-1664
presumptive neural plate1.35e-1664
neural tube1.83e-1652
neural rod1.83e-1652
future spinal cord1.83e-1652
neural keel1.83e-1652
ectoderm-derived structure5.68e-1595
ectoderm5.68e-1595
presumptive ectoderm5.68e-1595
brain6.05e-1547
future brain6.05e-1547
regional part of brain4.13e-1446
ecto-epithelium1.60e-1273
anterior neural tube3.19e-1240
pre-chordal neural plate5.25e-1249
regional part of forebrain1.60e-1139
forebrain1.60e-1139
future forebrain1.60e-1139
gray matter7.75e-1034
occipital lobe8.24e-1010
visual cortex8.24e-1010
neocortex8.24e-1010
brain grey matter2.19e-0829
regional part of telencephalon2.19e-0829
telencephalon2.19e-0829
regional part of cerebral cortex1.97e-0717


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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