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MCL coexpression mm9:1083

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:6100148..6100213,-p1@Nudcd3
Mm9::chr11:61393124..61393131,-p2@Epn2
Mm9::chr11:61393139..61393209,-p1@Epn2
Mm9::chr2:34681707..34681760,-p1@Fbxw2
Mm9::chr4:125933470..125933614,-p1@Mtap7d1
Mm9::chr7:112782039..112782115,-p1@Trim3
Mm9::chr9:45646655..45646675,+p1@Bace1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0009049aspartic-type signal peptidase activity0.0120528132361804
GO:0009003signal peptidase activity0.0321223493874419
GO:0004194pepsin A activity0.0321223493874419



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system1.10e-3173
nervous system1.32e-3175
ectoderm-derived structure4.11e-2995
ectoderm4.11e-2995
presumptive ectoderm4.11e-2995
regional part of nervous system1.29e-2454
neural tube3.31e-2352
neural rod3.31e-2352
future spinal cord3.31e-2352
neural keel3.31e-2352
neurectoderm1.23e-2264
neural plate1.23e-2264
presumptive neural plate1.23e-2264
ecto-epithelium4.41e-2173
structure with developmental contribution from neural crest9.91e-2192
brain3.05e-2047
future brain3.05e-2047
regional part of brain1.11e-1946
gray matter1.48e-1934
brain grey matter6.73e-1729
regional part of telencephalon6.73e-1729
telencephalon6.73e-1729
anterior neural tube2.46e-1640
regional part of forebrain8.37e-1639
forebrain8.37e-1639
future forebrain8.37e-1639
pre-chordal neural plate1.91e-1549
tube8.82e-15114
anatomical conduit1.01e-14122
cerebral cortex1.68e-1221
cerebral hemisphere1.68e-1221
pallium1.68e-1221
regional part of cerebral cortex8.81e-1117
occipital lobe8.20e-0810
visual cortex8.20e-0810
neocortex8.20e-0810
posterior neural tube1.38e-0712
chordal neural plate1.38e-0712
multi-cellular organism1.64e-07333


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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