MCL coexpression mm9:3099

Phase1 CAGE Peaks

	Short description
Mm9::chr17:36032967..36033006,-	p5@2310061I04Rik
Mm9::chr1:75186924..75186955,-	p@chr1:75186924..75186955 -
Mm9::chr8:4243367..4243387,+	p@chr8:4243367..4243387 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0051403	stress-activated MAPK cascade	0.0141972933362336
GO:0004708	MAP kinase kinase activity	0.0141972933362336
GO:0005776	autophagic vacuole	0.0141972933362336
GO:0004712	protein serine/threonine/tyrosine kinase activity	0.0141972933362336
GO:0000045	autophagic vacuole formation	0.0141972933362336
GO:0016236	macroautophagy	0.0170874615623424
GO:0006914	autophagy	0.0259057528294619
GO:0043687	post-translational protein modification	0.0402724320478619
GO:0031098	stress-activated protein kinase signaling pathway	0.0402724320478619
GO:0006464	protein modification process	0.0435889154708822
GO:0043412	biopolymer modification	0.0435889154708822

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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