MCL coexpression mm9:2860
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Short description | |
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Mm9::chr13:55313414..55313447,+ | p2@Nsd1 |
Mm9::chr6:86354251..86354313,+ | p1@Tia1 |
Mm9::chr9:56266612..56266654,+ | p1@Hmg20a |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
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GO:0030331 | estrogen receptor binding | 0.00810825617706678 |
GO:0046966 | thyroid hormone receptor binding | 0.00810825617706678 |
GO:0046975 | histone lysine N-methyltransferase activity (H3-K36 specific) | 0.00810825617706678 |
GO:0016568 | chromatin modification | 0.00896215672069559 |
GO:0035258 | steroid hormone receptor binding | 0.00903808206770178 |
GO:0042974 | retinoic acid receptor binding | 0.00903808206770178 |
GO:0042799 | histone lysine N-methyltransferase activity (H4-K20 specific) | 0.00903808206770178 |
GO:0046965 | retinoid X receptor binding | 0.00903808206770178 |
GO:0006325 | establishment and/or maintenance of chromatin architecture | 0.00903808206770178 |
GO:0017091 | AU-rich element binding | 0.00903808206770178 |
GO:0006323 | DNA packaging | 0.00903808206770178 |
GO:0031324 | negative regulation of cellular metabolic process | 0.00933700986064206 |
GO:0016922 | ligand-dependent nuclear receptor binding | 0.00935362998129836 |
GO:0009892 | negative regulation of metabolic process | 0.0102114007393278 |
GO:0051276 | chromosome organization and biogenesis | 0.0114543722633916 |
GO:0035097 | histone methyltransferase complex | 0.0114543722633916 |
GO:0010468 | regulation of gene expression | 0.0114543722633916 |
GO:0031323 | regulation of cellular metabolic process | 0.0122039355836149 |
GO:0042036 | negative regulation of cytokine biosynthetic process | 0.0122478024990145 |
GO:0019222 | regulation of metabolic process | 0.0122478024990145 |
GO:0035257 | nuclear hormone receptor binding | 0.0127345656648945 |
GO:0051427 | hormone receptor binding | 0.0132600607150388 |
GO:0016571 | histone methylation | 0.0158518140714068 |
GO:0018024 | histone-lysine N-methyltransferase activity | 0.0158907178865336 |
GO:0016278 | lysine N-methyltransferase activity | 0.0158907178865336 |
GO:0016279 | protein-lysine N-methyltransferase activity | 0.0158907178865336 |
GO:0010467 | gene expression | 0.0168146204921224 |
GO:0006259 | DNA metabolic process | 0.017233100952645 |
GO:0042054 | histone methyltransferase activity | 0.0198737457423813 |
GO:0017148 | negative regulation of translation | 0.0198737457423813 |
GO:0031327 | negative regulation of cellular biosynthetic process | 0.0198737457423813 |
GO:0006479 | protein amino acid methylation | 0.0198737457423813 |
GO:0008213 | protein amino acid alkylation | 0.0198737457423813 |
GO:0001702 | gastrulation with mouth forming second | 0.0210871265304523 |
GO:0050794 | regulation of cellular process | 0.0210871265304523 |
GO:0009890 | negative regulation of biosynthetic process | 0.0210871265304523 |
GO:0008170 | N-methyltransferase activity | 0.0210871265304523 |
GO:0008276 | protein methyltransferase activity | 0.0210871265304523 |
GO:0016570 | histone modification | 0.0211678896003258 |
GO:0048523 | negative regulation of cellular process | 0.0216028946271842 |
GO:0016569 | covalent chromatin modification | 0.0219083509771772 |
GO:0048519 | negative regulation of biological process | 0.0236369750219196 |
GO:0043414 | biopolymer methylation | 0.0236369750219196 |
GO:0050789 | regulation of biological process | 0.0236369750219196 |
GO:0032259 | methylation | 0.0242661749924914 |
GO:0042035 | regulation of cytokine biosynthetic process | 0.026369046303537 |
GO:0003714 | transcription corepressor activity | 0.0288954535041561 |
GO:0065007 | biological regulation | 0.0289057852480629 |
GO:0042089 | cytokine biosynthetic process | 0.0289057852480629 |
GO:0042107 | cytokine metabolic process | 0.0289057852480629 |
GO:0005634 | nucleus | 0.0289057852480629 |
GO:0007369 | gastrulation | 0.0289057852480629 |
GO:0006996 | organelle organization and biogenesis | 0.0291273914862101 |
GO:0051248 | negative regulation of protein metabolic process | 0.0305188836318489 |
GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | 0.0308419047956447 |
GO:0006730 | one-carbon compound metabolic process | 0.0333074784707566 |
GO:0003682 | chromatin binding | 0.0412973269226017 |
GO:0001816 | cytokine production | 0.0412973269226017 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
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