MCL coexpression mm9:858

Phase1 CAGE Peaks

	Short description
Mm9::chr10:127806178..127806254,-	p@chr10:127806178..127806254 -
Mm9::chr11:60541983..60542004,+	p2@Smcr7
Mm9::chr11:94902580..94902585,-	p6@Pdk2
Mm9::chr11:94902590..94902611,-	p3@Pdk2
Mm9::chr11:94902622..94902644,-	p2@Pdk2
Mm9::chr11:94902649..94902688,-	p1@Pdk2
Mm9::chr17:36034287..36034314,-	p1@2310061I04Rik
Mm9::chr8:23587095..23587158,-	p2@AI316807

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	0.0124219511511219
GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity	0.0124219511511219
GO:0018106	peptidyl-histidine phosphorylation	0.0124219511511219
GO:0006085	acetyl-CoA biosynthetic process	0.0124219511511219
GO:0018202	peptidyl-histidine modification	0.0124219511511219
GO:0004673	protein histidine kinase activity	0.0172489287925781
GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	0.0206941778467661
GO:0006090	pyruvate metabolic process	0.0271506902753816
GO:0006084	acetyl-CoA metabolic process	0.0390461747357361

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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