MCL coexpression mm9:744

Phase1 CAGE Peaks

	Short description
Mm9::chr2:109533758..109533781,+	p1@Bdnf
Mm9::chr5:114824999..114825005,-	p@chr5:114824999..114825005 -
Mm9::chr7:96658543..96658553,-	p@chr7:96658543..96658553 -
Mm9::chr7:96659061..96659074,-	p@chr7:96659061..96659074 -
Mm9::chr7:96666044..96666075,-	p1@Prss23
Mm9::chr7:96666086..96666097,-	p2@Prss23
Mm9::chr7:96666381..96666395,-	p3@Prss23
Mm9::chr7:96666663..96666719,-	p@chr7:96666663..96666719 -
Mm9::chr7:96667044..96667065,-	p@chr7:96667044..96667065 -
Mm9::chr9:106378465..106378488,-	p2@Parp3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007412	axon target recognition	0.0238251708586333
GO:0046668	regulation of retinal cell programmed cell death	0.0238251708586333
GO:0014047	glutamate secretion	0.0238251708586333
GO:0045666	positive regulation of neuron differentiation	0.0238251708586333
GO:0046666	retinal cell programmed cell death	0.0238251708586333
GO:0007406	negative regulation of neuroblast proliferation	0.0238251708586333
GO:0021675	nerve development	0.0340284989785554
GO:0008038	neuron recognition	0.0357260081764982
GO:0042596	fear response	0.0385149342631411
GO:0050768	negative regulation of neurogenesis	0.0385149342631411
GO:0048167	regulation of synaptic plasticity	0.0385149342631411
GO:0050803	regulation of synapse structure and activity	0.0385149342631411
GO:0043524	negative regulation of neuron apoptosis	0.0385149342631411
GO:0033555	multicellular organismal response to stress	0.0385149342631411
GO:0007405	neuroblast proliferation	0.0385149342631411
GO:0045664	regulation of neuron differentiation	0.0385149342631411
GO:0042493	response to drug	0.0385149342631411
GO:0001657	ureteric bud development	0.0385149342631411
GO:0042490	mechanoreceptor differentiation	0.0385149342631411
GO:0043523	regulation of neuron apoptosis	0.0385149342631411
GO:0007631	feeding behavior	0.0385149342631411
GO:0051402	neuron apoptosis	0.0390556255448681
GO:0016358	dendrite development	0.0390556255448681
GO:0048592	eye morphogenesis	0.0390556255448681
GO:0008037	cell recognition	0.0390556255448681
GO:0050767	regulation of neurogenesis	0.0390556255448681
GO:0001656	metanephros development	0.0390556255448681
GO:0045597	positive regulation of cell differentiation	0.0390556255448681
GO:0007269	neurotransmitter secretion	0.0417962096486196
GO:0045055	regulated secretory pathway	0.049333415351641
GO:0007611	learning and/or memory	0.049333415351641
GO:0051094	positive regulation of developmental process	0.049333415351641
GO:0048839	inner ear development	0.049333415351641
GO:0001822	kidney development	0.049333415351641
GO:0043583	ear development	0.049333415351641
GO:0006916	anti-apoptosis	0.049333415351641
GO:0001655	urogenital system development	0.049333415351641
GO:0007411	axon guidance	0.049333415351641

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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