MCL coexpression mm9:316

Phase1 CAGE Peaks

	Short description
Mm9::chr10:127962917..127962936,-	p1@Esyt1
Mm9::chr11:68245614..68245672,+	p1@Pik3r5
Mm9::chr12:87027598..87027652,+	p1@Batf
Mm9::chr15:6530936..6530950,+	p@chr15:6530936..6530950 +
Mm9::chr15:6530960..6530979,+	p@chr15:6530960..6530979 +
Mm9::chr15:78391895..78391920,-	p@chr15:78391895..78391920 -
Mm9::chr15:78396374..78396387,-	p@chr15:78396374..78396387 -
Mm9::chr15:78427542..78427551,+	p2@Cyth4
Mm9::chr15:78427563..78427582,+	p1@Cyth4
Mm9::chr15:79572948..79572992,-	p2@Sun2
Mm9::chr16:91485540..91485554,+	p3@Ifnar1
Mm9::chr17:35400991..35401003,+	p7@H2-D1
Mm9::chr17:36004124..36004178,+	p@chr17:36004124..36004178 +
Mm9::chr19:3907087..3907117,-	p2@Tcirg1
Mm9::chr19:3935252..3935261,+	p2@Unc93b1
Mm9::chr1:34529559..34529602,+	p1@Ptpn18
Mm9::chr2:167328914..167328961,+	p1@Rnf114
Mm9::chr3:90070429..90070488,+	p1@Dennd4b
Mm9::chr4:130469179..130469263,+	p1@Laptm5
Mm9::chr4:149072707..149072726,-	p1@Pik3cd
Mm9::chr5:138070397..138070430,+	p1@Lrch4-sap25 p1@Lrch4
Mm9::chr5:139848167..139848196,-	p@chr5:139848167..139848196 -
Mm9::chr6:124678463..124678472,-	p@chr6:124678463..124678472 -
Mm9::chr7:108510511..108510558,+	p4@Arap1
Mm9::chr7:31827125..31827193,-	p1@Fxyd5

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0048002	antigen processing and presentation of peptide antigen	0.0208037826654645
GO:0019882	antigen processing and presentation	0.0294189354332319

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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