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MCL coexpression mm9:976

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Phase1 CAGE Peaks

 Short description
Mm9::chr18:38498588..38498639,-p1@Gnpda1
Mm9::chr18:38498651..38498661,-p2@Gnpda1
Mm9::chr2:125691960..125692018,+p1@Galk2
Mm9::chr2:125692019..125692041,+p2@Galk2
Mm9::chr2:164659341..164659352,+p3@Ctsa
Mm9::chr2:25211831..25211838,-p2@Dpp7
Mm9::chr9:114310210..114310251,+p1@Tmppe
p2@Glb1
Mm9::chrX:71176090..71176162,-p1@Renbp


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0016861intramolecular oxidoreductase activity, interconverting aldoses and ketoses0.000128857921359924
GO:0019318hexose metabolic process0.000128857921359924
GO:0005996monosaccharide metabolic process0.000128857921359924
GO:0006041glucosamine metabolic process0.000185210849153496
GO:0006044N-acetylglucosamine metabolic process0.000185210849153496
GO:0006040amino sugar metabolic process0.000278238433679989
GO:0044262cellular carbohydrate metabolic process0.000329345436162799
GO:0006066alcohol metabolic process0.000329345436162799
GO:0016860intramolecular oxidoreductase activity0.000605618978561636
GO:0005975carbohydrate metabolic process0.000668734135780982
GO:0008238exopeptidase activity0.00184444566190033
GO:0004186carboxypeptidase C activity0.00184444566190033
GO:0046370fructose biosynthetic process0.00184444566190033
GO:0050121N-acylglucosamine 2-epimerase activity0.00184444566190033
GO:0006002fructose 6-phosphate metabolic process0.00184444566190033
GO:0004476mannose-6-phosphate isomerase activity0.00307373925502968
GO:0004342glucosamine-6-phosphate deaminase activity0.00307373925502968
GO:0004335galactokinase activity0.00307373925502968
GO:0016853isomerase activity0.00360238329815844
GO:0005764lysosome0.0040717293324298
GO:0000323lytic vacuole0.0040717293324298
GO:0005773vacuole0.00467577611898372
GO:0004185serine carboxypeptidase activity0.00467577611898372
GO:0008236serine-type peptidase activity0.00467577611898372
GO:0017171serine hydrolase activity0.00467577611898372
GO:0006000fructose metabolic process0.00512121488680332
GO:0006012galactose metabolic process0.00512121488680332
GO:0046835carbohydrate phosphorylation0.00592532787518543
GO:0016857racemase and epimerase activity, acting on carbohydrates and derivatives0.00667377588904681
GO:0043170macromolecule metabolic process0.0071181114580042
GO:0007340acrosome reaction0.00863731630838491
GO:0006013mannose metabolic process0.00863731630838491
GO:0009308amine metabolic process0.00950603627406468
GO:0016854racemase and epimerase activity0.00975294890479075
GO:0006807nitrogen compound metabolic process0.010354764594616
GO:0044238primary metabolic process0.0120339471230969
GO:0044237cellular metabolic process0.0120339471230969
GO:0017156calcium ion-dependent exocytosis0.0145311266733661
GO:0019239deaminase activity0.0148648313442383
GO:0019319hexose biosynthetic process0.0158700377757918
GO:0046165alcohol biosynthetic process0.0164250103375253
GO:0046364monosaccharide biosynthetic process0.0164250103375253
GO:0019200carbohydrate kinase activity0.0186017631602618
GO:0004177aminopeptidase activity0.0231050532608269
GO:0006508proteolysis0.0231050532608269
GO:0007338single fertilization0.0243720217087801
GO:0004180carboxypeptidase activity0.0243720217087801
GO:0016787hydrolase activity0.0243720217087801
GO:0008233peptidase activity0.0252410139007344
GO:0009566fertilization0.026971109984213
GO:0016051carbohydrate biosynthetic process0.0424914869646335
GO:0006887exocytosis0.044810011066312



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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