MCL coexpression mm9:931

Phase1 CAGE Peaks

	Short description
Mm9::chr12:120476420..120476474,-	p2@Itgb8
Mm9::chr12:120476479..120476491,-	p14@Itgb8
Mm9::chr12:120476493..120476534,-	p3@Itgb8
Mm9::chr12:120476537..120476565,-	p7@Itgb8
Mm9::chr12:120476571..120476595,-	p8@Itgb8
Mm9::chr13:78341625..78341649,+	p1@ENSMUST00000123998 p1@uc007rhf.1
Mm9::chr18:31402796..31402840,-	p@chr18:31402796..31402840 -
Mm9::chrX:82018139..82018149,+	p28@Dmd

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045213	neurotransmitter receptor metabolic process	0.0214694502798881
GO:0001573	ganglioside metabolic process	0.0214694502798881
GO:0046716	muscle maintenance	0.0214694502798881
GO:0006687	glycosphingolipid metabolic process	0.0214694502798881
GO:0005626	insoluble fraction	0.0214694502798881
GO:0016010	dystrophin-associated glycoprotein complex	0.0214694502798881
GO:0006664	glycolipid metabolic process	0.0220869754310361
GO:0006672	ceramide metabolic process	0.0220869754310361
GO:0043112	receptor metabolic process	0.0220869754310361
GO:0046519	sphingoid metabolic process	0.0220869754310361
GO:0005605	basal lamina	0.0220869754310361
GO:0042383	sarcolemma	0.0220869754310361
GO:0030018	Z disc	0.0220869754310361
GO:0008305	integrin complex	0.0220869754310361
GO:0031674	I band	0.0220869754310361
GO:0045121	lipid raft	0.0220869754310361
GO:0030055	cell-matrix junction	0.0220869754310361
GO:0006665	sphingolipid metabolic process	0.0250271009001221
GO:0044459	plasma membrane part	0.0284517783662214
GO:0005604	basement membrane	0.0284517783662214
GO:0007160	cell-matrix adhesion	0.0284517783662214
GO:0030017	sarcomere	0.0284517783662214
GO:0043234	protein complex	0.0284517783662214
GO:0031589	cell-substrate adhesion	0.0284517783662214
GO:0044449	contractile fiber part	0.0284517783662214
GO:0016323	basolateral plasma membrane	0.0284517783662214
GO:0043235	receptor complex	0.0284517783662214
GO:0030016	myofibril	0.0284517783662214
GO:0043292	contractile fiber	0.0284517783662214
GO:0007229	integrin-mediated signaling pathway	0.0317880550489242
GO:0044420	extracellular matrix part	0.0317880550489242
GO:0007519	skeletal muscle development	0.0317962327730742
GO:0005886	plasma membrane	0.0318918771747741
GO:0032991	macromolecular complex	0.0333212854780622
GO:0014706	striated muscle development	0.0370887258834726
GO:0007275	multicellular organismal development	0.0370887258834726
GO:0006643	membrane lipid metabolic process	0.0430424443421253
GO:0005792	microsome	0.0430424443421253
GO:0042598	vesicular fraction	0.0430424443421253
GO:0007517	muscle development	0.0443611126509407
GO:0007268	synaptic transmission	0.0495036423669913

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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