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MCL coexpression mm9:909

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:62272200..62272221,-p11@Ncor1
Mm9::chr16:4679660..4679699,-p2@Coro7
Mm9::chr2:155805181..155805202,-p@chr2:155805181..155805202
-
Mm9::chr7:134281321..134281341,-p1@Spn
Mm9::chr7:150191554..150191578,+p2@Tspan32
Mm9::chr7:82731110..82731121,+p@chr7:82731110..82731121
+
Mm9::chr7:82731147..82731158,+p@chr7:82731147..82731158
+
Mm9::chr8:114060166..114060201,+p2@Znrf1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0001808negative regulation of type IV hypersensitivity0.0112754494454306
GO:0002710negative regulation of T cell mediated immunity0.0112754494454306
GO:0001807regulation of type IV hypersensitivity0.0112754494454306
GO:0001806type IV hypersensitivity0.0112754494454306
GO:0008367bacterial binding0.0112754494454306
GO:0002704negative regulation of leukocyte mediated immunity0.0112754494454306
GO:0002865negative regulation of acute inflammatory response to antigenic stimulus0.0112754494454306
GO:0050688regulation of defense response to virus0.0112754494454306
GO:0002862negative regulation of inflammatory response to antigenic stimulus0.0112754494454306
GO:0002884negative regulation of hypersensitivity0.0112754494454306
GO:0002674negative regulation of acute inflammatory response0.0112754494454306
GO:0002707negative regulation of lymphocyte mediated immunity0.0112754494454306
GO:0002698negative regulation of immune effector process0.014495417890902
GO:0001562response to protozoan0.014495417890902
GO:0002709regulation of T cell mediated immunity0.0169057622049432
GO:0042535positive regulation of tumor necrosis factor biosynthetic process0.0169057622049432
GO:0031254trailing edge0.0169057622049432
GO:0002820negative regulation of adaptive immune response0.0169057622049432
GO:0001931uropod0.0169057622049432
GO:0002823negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains0.0169057622049432
GO:0042534regulation of tumor necrosis factor biosynthetic process0.0169057622049432
GO:0050777negative regulation of immune response0.0169057622049432
GO:0002683negative regulation of immune system process0.0169057622049432
GO:0042533tumor necrosis factor biosynthetic process0.0169057622049432
GO:0031294lymphocyte costimulation0.0186505461425434
GO:0045060negative thymic T cell selection0.0186505461425434
GO:0002456T cell mediated immunity0.0186505461425434
GO:0043383negative T cell selection0.0186505461425434
GO:0031295T cell costimulation0.0186505461425434
GO:0051607defense response to virus0.0202802464374892
GO:0031348negative regulation of defense response0.0213406109698887
GO:0050728negative regulation of inflammatory response0.0213406109698887
GO:0002883regulation of hypersensitivity0.0213406109698887
GO:0002673regulation of acute inflammatory response0.0213406109698887
GO:0002438acute inflammatory response to antigenic stimulus0.0213406109698887
GO:0002864regulation of acute inflammatory response to antigenic stimulus0.0213406109698887
GO:0002524hypersensitivity0.0213406109698887
GO:0000299integral to membrane of membrane fraction0.0213406109698887
GO:0007162negative regulation of cell adhesion0.0219975137052059
GO:0042130negative regulation of T cell proliferation0.0219975137052059
GO:0002861regulation of inflammatory response to antigenic stimulus0.0219975137052059
GO:0002437inflammatory response to antigenic stimulus0.0219975137052059
GO:0045061thymic T cell selection0.0219975137052059
GO:0032640tumor necrosis factor production0.0230305870421663
GO:0045058T cell selection0.024429934716648
GO:0002703regulation of leukocyte mediated immunity0.024429934716648
GO:0002706regulation of lymphocyte mediated immunity0.024429934716648
GO:0050868negative regulation of T cell activation0.0246732476426524
GO:0008624induction of apoptosis by extracellular signals0.0246732476426524
GO:0002697regulation of immune effector process0.0246732476426524
GO:0050672negative regulation of lymphocyte proliferation0.0246732476426524
GO:0032945negative regulation of mononuclear cell proliferation0.0246732476426524
GO:0002819regulation of adaptive immune response0.027501868906009
GO:0002822regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.0.027501868906009
GO:0033077T cell differentiation in the thymus0.0301260709408571
GO:0051250negative regulation of lymphocyte activation0.0301260709408571
GO:0042102positive regulation of T cell proliferation0.0319583419061254
GO:0031347regulation of defense response0.0326021990965578
GO:0051241negative regulation of multicellular organismal process0.0326021990965578
GO:0050727regulation of inflammatory response0.0326021990965578
GO:0042108positive regulation of cytokine biosynthetic process0.0353734580124094
GO:0032946positive regulation of mononuclear cell proliferation0.0385149164805372
GO:0050671positive regulation of lymphocyte proliferation0.0385149164805372
GO:0045727positive regulation of translation0.0421072289428701
GO:0042129regulation of T cell proliferation0.0432242556945791
GO:0050870positive regulation of T cell activation0.0432242556945791
GO:0031328positive regulation of cellular biosynthetic process0.0432242556945791
GO:0048583regulation of response to stimulus0.0435742622990178
GO:0030155regulation of cell adhesion0.0439139104015371
GO:0009615response to virus0.0471136079639364
GO:0042035regulation of cytokine biosynthetic process0.0473928022269503
GO:0050670regulation of lymphocyte proliferation0.0481839177904082
GO:0032944regulation of mononuclear cell proliferation0.0481839177904082
GO:0009891positive regulation of biosynthetic process0.0481839177904082
GO:0042098T cell proliferation0.0486756628513152
GO:0005625soluble fraction0.0486756628513152



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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