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MCL coexpression mm9:906

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:53670461..53670487,+p@chr11:53670461..53670487
+
Mm9::chr16:10489821..10489850,+p4@Ciita
Mm9::chr16:10489852..10489897,+p2@Ciita
Mm9::chr16:55816886..55816906,+p@chr16:55816886..55816906
+
Mm9::chr17:34290110..34290184,+p1@H2-DMb1
Mm9::chr17:84555738..84555750,-p@chr17:84555738..84555750
-
Mm9::chr5:73948518..73948529,+p@chr5:73948518..73948529
+
Mm9::chr5:73948543..73948565,+p@chr5:73948543..73948565
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042613MHC class II protein complex0.0195077156806841
GO:0051085chaperone cofactor-dependent protein folding0.0195077156806841
GO:0006458'de novo' protein folding0.0195077156806841
GO:0051084'de novo' posttranslational protein folding0.0195077156806841
GO:0002495antigen processing and presentation of peptide antigen via MHC class II0.0195077156806841
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II0.0195077156806841
GO:0002478antigen processing and presentation of exogenous peptide antigen0.0195077156806841
GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class II0.0195077156806841
GO:0019884antigen processing and presentation of exogenous antigen0.0209884571534992
GO:0042611MHC protein complex0.0221723299436552
GO:0048002antigen processing and presentation of peptide antigen0.0253775944494857
GO:0019882antigen processing and presentation0.0389747969703214



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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