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MCL coexpression mm9:1677

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Phase1 CAGE Peaks

 Short description
Mm9::chr15:39491058..39491131,+p1@Rims2
Mm9::chr15:72378118..72378137,-p@chr15:72378118..72378137
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Mm9::chr1:75543215..75543229,+p6@Slc4a3
Mm9::chr4:122878468..122878513,+p4@Nt5c1a
Mm9::chr4:122878746..122878772,+p2@Nt5c1a


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:00082535'-nucleotidase activity0.0242162498772717
GO:0005452inorganic anion exchanger activity0.0242162498772717
GO:0008252nucleotidase activity0.0242162498772717
GO:0015380anion exchanger activity0.0242162498772717
GO:0015106bicarbonate transmembrane transporter activity0.0242162498772717
GO:0015301anion:anion antiporter activity0.0242162498772717
GO:0015108chloride transmembrane transporter activity0.0242162498772717
GO:0017137Rab GTPase binding0.0313776749010759
GO:0017156calcium ion-dependent exocytosis0.0313776749010759
GO:0030073insulin secretion0.0314828234138316
GO:0030072peptide hormone secretion0.0314828234138316
GO:0015103inorganic anion transmembrane transporter activity0.0314828234138316
GO:0002790peptide secretion0.0314828234138316
GO:0015297antiporter activity0.035735271435484
GO:0015833peptide transport0.035735271435484
GO:0046879hormone secretion0.0361407521892148
GO:0006836neurotransmitter transport0.0378365687345399
GO:0017016Ras GTPase binding0.0378365687345399
GO:0031267small GTPase binding0.0378365687345399
GO:0051020GTPase binding0.038755433051013
GO:0019933cAMP-mediated signaling0.0402543445152911
GO:0019935cyclic-nucleotide-mediated signaling0.040339193295129



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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