MCL coexpression mm9:1561

Phase1 CAGE Peaks

	Short description
Mm9::chr11:32177293..32177304,+	p@chr11:32177293..32177304 +
Mm9::chr7:111000297..111000324,-	p@chr7:111000297..111000324 -
Mm9::chr7:111000331..111000338,-	p@chr7:111000331..111000338 -
Mm9::chr7:111000379..111000390,-	p@chr7:111000379..111000390 -
Mm9::chr7:111001713..111001727,-	p1@Hbb-y

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005833	hemoglobin complex	2.34126131238934e-06
GO:0019825	oxygen binding	2.80951357486722e-06
GO:0005344	oxygen transporter activity	2.84073039236574e-06
GO:0015671	oxygen transport	2.84073039236574e-06
GO:0015669	gas transport	2.84073039236574e-06
GO:0044445	cytosolic part	0.000113707257738376
GO:0020037	heme binding	0.000119111669267808
GO:0046906	tetrapyrrole binding	0.000119111669267808
GO:0005506	iron ion binding	0.000746966414710529
GO:0005829	cytosol	0.000883685669748234
GO:0022892	substrate-specific transporter activity	0.00581718299353757
GO:0043234	protein complex	0.0157762381643388
GO:0032991	macromolecular complex	0.0231208919643697
GO:0006810	transport	0.026242027419916
GO:0046914	transition metal ion binding	0.026242027419916
GO:0051234	establishment of localization	0.026242027419916
GO:0051179	localization	0.0314763853360248
GO:0044444	cytoplasmic part	0.0405311614336615
GO:0043169	cation binding	0.0409248041331591
GO:0046872	metal ion binding	0.0454595127799532
GO:0043167	ion binding	0.0454595127799532

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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