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MCL coexpression mm9:972

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Phase1 CAGE Peaks

 Short description
Mm9::chr18:15561235..15561295,-p2@Aqp4
Mm9::chr18:15562125..15562144,-p3@Aqp4
Mm9::chr18:15562149..15562166,-p1@Aqp4
Mm9::chr18:15562167..15562176,-p5@Aqp4
Mm9::chr18:15562189..15562196,-p7@Aqp4
Mm9::chr18:15562199..15562210,-p6@Aqp4
Mm9::chr2:26185946..26185961,+p4@Gpsm1
Mm9::chr7:107802465..107802479,-p8@Plekhb1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030104water homeostasis0.0189727819534409
GO:0018987osmoregulation0.0189727819534409
GO:0015250water channel activity0.0189727819534409
GO:0005372water transporter activity0.0189727819534409
GO:0006833water transport0.0189727819534409
GO:0042044fluid transport0.0189727819534409
GO:0001750photoreceptor outer segment0.0195412882118183
GO:0005794Golgi apparatus0.0195412882118183
GO:0031513nonmotile primary cilium0.0195412882118183



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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