MCL coexpression mm9:185

Phase1 CAGE Peaks

	Short description
Mm9::chr10:122608843..122608894,-	p@chr10:122608843..122608894 -
Mm9::chr10:20611321..20611361,-	p@chr10:20611321..20611361 -
Mm9::chr10:36348041..36348054,+	p@chr10:36348041..36348054 +
Mm9::chr11:21270681..21270692,-	p5@Ugp2
Mm9::chr11:66926940..66926976,-	p@chr11:66926940..66926976 -
Mm9::chr11:67013593..67013609,+	p1@Myh1
Mm9::chr11:67029448..67029459,-	p@chr11:67029448..67029459 -
Mm9::chr11:87975881..87975888,+	p16@Cuedc1
Mm9::chr13:83518057..83518059,-	p@chr13:83518057..83518059 -
Mm9::chr13:83643136..83643158,+	p7@Mef2c
Mm9::chr14:31693672..31693685,+	p@chr14:31693672..31693685 +
Mm9::chr15:24236671..24236673,-	p@chr15:24236671..24236673 -
Mm9::chr15:76993404..76993415,-	p@chr15:76993404..76993415 -
Mm9::chr16:20678283..20678329,+	p11@Eif4g1
Mm9::chr16:57352884..57352895,+	p11@Filip1l
Mm9::chr17:7342812..7342832,+	p@chr17:7342812..7342832 +
Mm9::chr18:60751417..60751432,-	p2@Myoz3
Mm9::chr19:30699939..30699952,-	p@chr19:30699939..30699952 -
Mm9::chr19:43602850..43602863,+	p@chr19:43602850..43602863 +
Mm9::chr1:12982731..12982747,-	p@chr1:12982731..12982747 -
Mm9::chr1:185863421..185863436,+	p@chr1:185863421..185863436 +
Mm9::chr1:66992035..66992057,-	p8@Myl1
Mm9::chr1:94009904..94009911,-	p@chr1:94009904..94009911 -
Mm9::chr2:181314020..181314044,+	p1@ENSMUST00000126672
Mm9::chr2:181314061..181314072,+	p2@ENSMUST00000126672
Mm9::chr2:69507955..69507970,+	p3@Kbtbd10
Mm9::chr3:122820113..122820116,-	p@chr3:122820113..122820116 -
Mm9::chr3:69352872..69352898,+	p4@Ppm1l
Mm9::chr4:124377615..124377628,+	p3@Fhl3
Mm9::chr4:124377944..124377972,+	p1@Fhl3
Mm9::chr4:128964917..128964929,+	p5@Sync
Mm9::chr4:133712837..133712847,-	p5@Ccdc21
Mm9::chr4:137591803..137591812,+	p@chr4:137591803..137591812 +
Mm9::chr4:148688115..148688131,-	p@chr4:148688115..148688131 -
Mm9::chr4:43528040..43528062,-	p@chr4:43528040..43528062 -
Mm9::chr4:43536708..43536719,-	p10@Tpm2
Mm9::chr4:57262011..57262022,-	p@chr4:57262011..57262022 -
Mm9::chr4:73596402..73596419,-	p@chr4:73596402..73596419 -
Mm9::chr4:73596683..73596694,-	p3@2310002L09Rik
Mm9::chr4:73596718..73596737,-	p2@2310002L09Rik
Mm9::chr4:73596738..73596757,-	p1@2310002L09Rik
Mm9::chr6:108888660..108888701,-	p@chr6:108888660..108888701 -
Mm9::chr6:128247107..128247125,-	p@chr6:128247107..128247125 -
Mm9::chr7:109248409..109248420,-	p4@Art5
Mm9::chr7:119885584..119885594,+	p8@Tead1
Mm9::chr7:52693378..52693403,+	p@chr7:52693378..52693403 +
Mm9::chr7:52699829..52699843,+	p@chr7:52699829..52699843 +
Mm9::chr7:83374655..83374680,+	p1@Agbl1
Mm9::chr7:83374741..83374752,+	p2@Agbl1
Mm9::chr9:41793716..41793730,-	p@chr9:41793716..41793730 -
Mm9::chr9:65112980..65112994,+	p1@Cilp
Mm9::chr9:72541001..72541016,+	p@chr9:72541001..72541016 +
Mm9::chr9:77195696..77195713,-	p3@2310046A06Rik
Mm9::chrX:54032726..54032742,+	p10@Fhl1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030017	sarcomere	9.36064978987318e-07
GO:0044449	contractile fiber part	9.36064978987318e-07
GO:0030016	myofibril	9.36064978987318e-07
GO:0043292	contractile fiber	9.36064978987318e-07
GO:0030018	Z disc	0.000219674389835757
GO:0031674	I band	0.000269104593422744
GO:0015629	actin cytoskeleton	0.00160500281119455
GO:0044430	cytoskeletal part	0.0055326680755427
GO:0007517	muscle development	0.0198485050763202
GO:0007507	heart development	0.0198485050763202
GO:0007275	multicellular organismal development	0.020504372274795
GO:0007010	cytoskeleton organization and biogenesis	0.0214133097494737
GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity	0.0214133097494737
GO:0051748	UDP-sugar pyrophosphorylase activity	0.0214133097494737
GO:0005856	cytoskeleton	0.0285012800517676
GO:0016459	myosin complex	0.0285012800517676
GO:0048513	organ development	0.0289571979001108
GO:0003779	actin binding	0.0299638512855307
GO:0004692	cGMP-dependent protein kinase activity	0.0299638512855307
GO:0004373	glycogen (starch) synthase activity	0.0299638512855307
GO:0003953	NAD+ nucleosidase activity	0.0398662947341668
GO:0005515	protein binding	0.0398662947341668
GO:0003012	muscle system process	0.0398662947341668
GO:0006936	muscle contraction	0.0398662947341668
GO:0004690	cyclic nucleotide-dependent protein kinase activity	0.0460527909081036
GO:0005862	muscle thin filament tropomyosin	0.0460527909081036
GO:0032502	developmental process	0.0486883141716843
GO:0008092	cytoskeletal protein binding	0.0486883141716843
GO:0048731	system development	0.0493006131586607

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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