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Coexpression cluster:C2647

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Full id: C2647_Adipocyte_Preadipocyte_tenocyte_Osteoblast_basal_Mesenchymal_Olfactory



Phase1 CAGE Peaks

Hg19::chr22:43023683..43023702,-p@chr22:43023683..43023702
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Hg19::chr22:43024232..43024253,-p5@CYB5R3
Hg19::chr22:43026936..43026976,-p4@CYB5R3
Hg19::chr22:43026982..43027003,-p10@CYB5R3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell1.01e-17180
somatic cell6.64e-14591
fibroblast8.95e-1475
mesodermal cell1.20e-10119
contractile cell7.71e-0959
somatic stem cell8.43e-09436
multi fate stem cell1.23e-08430
smooth muscle cell3.20e-0842
smooth muscle myoblast3.20e-0842
embryonic cell3.60e-08248
fat cell3.86e-0815
muscle precursor cell4.69e-0857
myoblast4.69e-0857
multi-potent skeletal muscle stem cell4.69e-0857
stem cell7.31e-08444
animal cell1.47e-07679
eukaryotic cell1.47e-07679
muscle cell2.75e-0754
Uber Anatomy
Ontology termp-valuen
trunk mesenchyme2.19e-12143
vasculature2.80e-1079
vascular system2.80e-1079
somite9.08e-1083
paraxial mesoderm9.08e-1083
presomitic mesoderm9.08e-1083
presumptive segmental plate9.08e-1083
trunk paraxial mesoderm9.08e-1083
presumptive paraxial mesoderm9.08e-1083
epithelial tube9.38e-10118
vessel1.62e-0969
multi-cellular organism1.65e-09659
dermomyotome4.10e-0970
multilaminar epithelium3.58e-0882
surface structure4.33e-0895
blood vessel6.56e-0860
epithelial tube open at both ends6.56e-0860
blood vasculature6.56e-0860
vascular cord6.56e-0860
splanchnic layer of lateral plate mesoderm7.85e-0884
anatomical system1.07e-07625
anatomical group1.39e-07626
integument2.21e-0745
integumental system2.21e-0745
circulatory system2.26e-07113
skeletal muscle tissue2.66e-0761
striated muscle tissue2.66e-0761
myotome2.66e-0761
muscle tissue4.16e-0763
musculature4.16e-0763
musculature of body4.16e-0763
trunk4.55e-07216
anatomical cluster4.91e-07286
cardiovascular system4.99e-07110
artery6.47e-0742
arterial blood vessel6.47e-0742
arterial system6.47e-0742
organism subdivision8.63e-07365


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.