Personal tools

Coexpression cluster:C1416

From FANTOM5_SSTAR

Revision as of 13:58, 12 September 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C1416_corpus_diencephalon_medulla_spinal_thalamus_caudate_occipital



Phase1 CAGE Peaks

Hg19::chr15:93827399..93827403,+p@chr15:93827399..93827403
+
Hg19::chr16:70759540..70759547,+p@chr16:70759540..70759547
+
Hg19::chr17:73689469..73689476,-p@chr17:73689469..73689476
-
Hg19::chr1:234659231..234659238,-p@chr1:234659231..234659238
-
Hg19::chr5:7654271..7654280,+p14@ADCY2
Hg19::chr6:39335288..39335291,+p@chr6:39335288..39335291
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.02e-6957
neural rod1.02e-6957
future spinal cord1.02e-6957
neural keel1.02e-6957
regional part of brain5.14e-5659
central nervous system1.46e-5582
neural plate1.35e-5286
presumptive neural plate1.35e-5286
neurectoderm2.88e-5290
brain1.05e-5169
future brain1.05e-5169
regional part of forebrain1.99e-4941
forebrain1.99e-4941
future forebrain1.99e-4941
regional part of nervous system7.73e-4994
nervous system7.73e-4994
anterior neural tube4.36e-4842
telencephalon4.11e-4034
gray matter9.06e-4034
brain grey matter9.06e-4034
adult organism3.09e-39115
regional part of telencephalon1.13e-3733
pre-chordal neural plate1.45e-3561
cerebral hemisphere3.53e-3532
head2.24e-31123
regional part of cerebral cortex4.43e-3022
anterior region of body2.02e-29129
craniocervical region2.02e-29129
tube1.08e-26194
cerebral cortex4.22e-2625
pallium4.22e-2625
ectoderm1.83e-25173
presumptive ectoderm1.83e-25173
neocortex3.05e-2520
ectoderm-derived structure5.32e-25169
posterior neural tube5.13e-2215
chordal neural plate5.13e-2215
anatomical conduit4.45e-20241
brainstem6.32e-188
anatomical cluster6.94e-16286
nucleus of brain1.94e-159
neural nucleus1.94e-159
segmental subdivision of hindbrain1.33e-1412
hindbrain1.33e-1412
presumptive hindbrain1.33e-1412
epithelium2.17e-14309
cell layer3.96e-14312
segmental subdivision of nervous system2.30e-1313
organism subdivision3.51e-13365
gyrus1.72e-126
basal ganglion1.35e-119
nuclear complex of neuraxis1.35e-119
aggregate regional part of brain1.35e-119
collection of basal ganglia1.35e-119
cerebral subcortex1.35e-119
telencephalic nucleus1.38e-107
diencephalon1.41e-107
future diencephalon1.41e-107
limbic system3.40e-105
medulla oblongata4.68e-103
myelencephalon4.68e-103
future myelencephalon4.68e-103
parietal lobe4.82e-105
spinal cord4.97e-103
pons1.24e-093
brainstem nucleus1.35e-093
middle temporal gyrus1.61e-093
temporal lobe2.66e-097
organ part5.19e-08219
multi-tissue structure7.27e-08347
regional part of metencephalon8.46e-089
metencephalon8.46e-089
future metencephalon8.46e-089
corpus striatum1.93e-074
striatum1.93e-074
ventral part of telencephalon1.93e-074
future corpus striatum1.93e-074
dorsal plus ventral thalamus3.00e-072
Ammon's horn4.43e-072
lobe parts of cerebral cortex4.43e-072
hippocampal formation4.43e-072
limbic lobe4.43e-072
caudate nucleus5.96e-072
future caudate nucleus5.96e-072
locus ceruleus6.90e-072
hindbrain nucleus6.90e-072


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.