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Coexpression cluster:C100

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Full id: C100_rhabdomyosarcoma_gastric_pineal_Wilms_cervical_mesodermal_endometrial



Phase1 CAGE Peaks

Hg19::chr10:127164948..127164949,+p@chr10:127164948..127164949
+
Hg19::chr10:15484275..15484286,-p@chr10:15484275..15484286
-
Hg19::chr10:15484431..15484442,-p@chr10:15484431..15484442
-
Hg19::chr10:26021734..26021737,+p@chr10:26021734..26021737
+
Hg19::chr10:29115087..29115093,-p@chr10:29115087..29115093
-
Hg19::chr10:29115210..29115211,-p@chr10:29115210..29115211
-
Hg19::chr10:29115374..29115386,-p@chr10:29115374..29115386
-
Hg19::chr10:29115387..29115397,-p@chr10:29115387..29115397
-
Hg19::chr10:29115473..29115484,-p@chr10:29115473..29115484
-
Hg19::chr10:29115553..29115564,-p@chr10:29115553..29115564
-
Hg19::chr10:29115582..29115596,-p@chr10:29115582..29115596
-
Hg19::chr10:47081891..47081936,+p@chr10:47081891..47081936
+
Hg19::chr10:52558260..52558284,+p@chr10:52558260..52558284
+
Hg19::chr10:54699580..54699590,+p@chr10:54699580..54699590
+
Hg19::chr10:54699682..54699687,+p@chr10:54699682..54699687
+
Hg19::chr10:7326214..7326248,-p@chr10:7326214..7326248
-
Hg19::chr10:73406056..73406065,+p@chr10:73406056..73406065
+
Hg19::chr10:78900371..78900394,-p@chr10:78900371..78900394
-
Hg19::chr10:97063520..97063523,-p@chr10:97063520..97063523
-
Hg19::chr10:97063551..97063560,-p@chr10:97063551..97063560
-
Hg19::chr11:12115624..12115629,+p47@MICAL2
Hg19::chr11:12115677..12115684,+p48@MICAL2
Hg19::chr11:37506770..37506779,+p@chr11:37506770..37506779
+
Hg19::chr11:555293..555305,+p@chr11:555293..555305
+
Hg19::chr11:555661..555679,+p@chr11:555661..555679
+
Hg19::chr11:557468..557509,-p@chr11:557468..557509
-
Hg19::chr11:557951..558000,+p1@ENST00000527620
p1@uc001lpy.2
Hg19::chr12:116440881..116440890,-p@chr12:116440881..116440890
-
Hg19::chr12:121078054..121078059,-p5@ENST00000544339
Hg19::chr12:121099016..121099027,+p@chr12:121099016..121099027
+
Hg19::chr12:26424754..26424761,-p1@ENST00000537525
Hg19::chr12:70351867..70351878,+p@chr12:70351867..70351878
+
Hg19::chr13:37785778..37785780,-p@chr13:37785778..37785780
-
Hg19::chr13:43687252..43687276,+p@chr13:43687252..43687276
+
Hg19::chr13:62245490..62245507,-p@chr13:62245490..62245507
-
Hg19::chr13:72444264..72444268,+p@chr13:72444264..72444268
+
Hg19::chr13:73043658..73043707,+p@chr13:73043658..73043707
+
Hg19::chr13:97762770..97762790,+p@chr13:97762770..97762790
+
Hg19::chr14:101124179..101124190,+p@chr14:101124179..101124190
+
Hg19::chr14:26755178..26755207,-p@chr14:26755178..26755207
-
Hg19::chr14:47355052..47355073,-p@chr14:47355052..47355073
-
Hg19::chr14:55916319..55916334,+p@chr14:55916319..55916334
+
Hg19::chr14:87200137..87200151,+p@chr14:87200137..87200151
+
Hg19::chr15:30165059..30165071,-p@chr15:30165059..30165071
-
Hg19::chr15:30165101..30165108,-p@chr15:30165101..30165108
-
Hg19::chr15:63889795..63889820,+p5@FBXL22
Hg19::chr15:63889822..63889832,+p6@FBXL22
Hg19::chr15:67692535..67692542,+p@chr15:67692535..67692542
+
Hg19::chr15:68125526..68125560,+p1@ENST00000560577
Hg19::chr15:99093792..99093831,+p@chr15:99093792..99093831
+
Hg19::chr16:11461647..11461671,+p@chr16:11461647..11461671
+
Hg19::chr16:69531031..69531041,+p@chr16:69531031..69531041
+
Hg19::chr16:75840422..75840442,+p@chr16:75840422..75840442
+
Hg19::chr17:70023350..70023353,-p@chr17:70023350..70023353
-
Hg19::chr17:71257414..71257417,-p@chr17:71257414..71257417
-
Hg19::chr18:24283454..24283475,-p3@LOC728606
Hg19::chr18:24283511..24283519,-p4@LOC728606
Hg19::chr18:25664943..25664973,-p@chr18:25664943..25664973
-
Hg19::chr18:25739260..25739277,-p54@CDH2
Hg19::chr18:63566669..63566685,-p@chr18:63566669..63566685
-
Hg19::chr18:6558132..6558147,+p@chr18:6558132..6558147
+
Hg19::chr18:68904448..68904456,+p@chr18:68904448..68904456
+
Hg19::chr19:1753137..1753142,+p@chr19:1753137..1753142
+
Hg19::chr19:1763746..1763749,+p@chr19:1763746..1763749
+
Hg19::chr19:43880636..43880651,-p@chr19:43880636..43880651
-
Hg19::chr19:54463760..54463771,+p@chr19:54463760..54463771
+
Hg19::chr19:54466179..54466202,+p1@CACNG8
Hg19::chr19:56169985..56170017,+p@chr19:56169985..56170017
+
Hg19::chr1:110982676..110982680,+p@chr1:110982676..110982680
+
Hg19::chr1:147727237..147727244,-p@chr1:147727237..147727244
-
Hg19::chr1:147727248..147727259,-p@chr1:147727248..147727259
-
Hg19::chr1:163175500..163175505,+p@chr1:163175500..163175505
+
Hg19::chr1:187341279..187341283,+p@chr1:187341279..187341283
+
Hg19::chr1:190678255..190678261,-p@chr1:190678255..190678261
-
Hg19::chr1:190682273..190682308,+p@chr1:190682273..190682308
+
Hg19::chr1:215259568..215259573,+p25@KCNK2
Hg19::chr1:234677747..234677751,+p@chr1:234677747..234677751
+
Hg19::chr20:10028340..10028345,+p@chr20:10028340..10028345
+
Hg19::chr20:10030576..10030604,-p@chr20:10030576..10030604
-
Hg19::chr20:10644940..10644945,-p@chr20:10644940..10644945
-
Hg19::chr20:10645342..10645345,-p@chr20:10645342..10645345
-
Hg19::chr20:24092542..24092549,-p@chr20:24092542..24092549
-
Hg19::chr20:6033220..6033224,-p10@AB527789
Hg19::chr20:6033446..6033457,-p6@AB527789
Hg19::chr20:6033657..6033666,-p11@AB527789
Hg19::chr21:17553910..17553945,+p@chr21:17553910..17553945
+
Hg19::chr2:172944910..172944923,+p@chr2:172944910..172944923
+
Hg19::chr2:172949196..172949198,+p21@DLX1
Hg19::chr2:202856838..202856850,-p@chr2:202856838..202856850
-
Hg19::chr2:202856858..202856864,-p@chr2:202856858..202856864
-
Hg19::chr2:202938005..202938019,+p2@LOC100652824
Hg19::chr2:238507633..238507638,-p@chr2:238507633..238507638
-
Hg19::chr2:242955807..242955813,+p@chr2:242955807..242955813
+
Hg19::chr2:44524032..44524049,+p@chr2:44524032..44524049
+
Hg19::chr2:98329652..98329687,+p9@ZAP70
Hg19::chr2:98329756..98329766,+p10@ZAP70
Hg19::chr2:98329858..98329869,+p7@ZAP70
Hg19::chr3:107553271..107553278,-p@chr3:107553271..107553278
-
Hg19::chr3:107553567..107553570,+p@chr3:107553567..107553570
+
Hg19::chr3:107601927..107601937,+p2@LOC285205
Hg19::chr3:107602030..107602044,+p1@LOC285205
Hg19::chr3:108189646..108189665,-p@chr3:108189646..108189665
-
Hg19::chr3:116911966..116911979,-p@chr3:116911966..116911979
-
Hg19::chr3:148924434..148924447,-p@chr3:148924434..148924447
-
Hg19::chr3:148925425..148925449,-p10@CP
Hg19::chr3:22370600..22370612,+p@chr3:22370600..22370612
+
Hg19::chr3:22370615..22370644,+p@chr3:22370615..22370644
+
Hg19::chr3:56950223..56950232,-p@chr3:56950223..56950232
-
Hg19::chr3:59842871..59842874,-p@chr3:59842871..59842874
-
Hg19::chr3:69299232..69299244,-p27@FRMD4B
Hg19::chr3:98222615..98222623,-p@chr3:98222615..98222623
-
Hg19::chr4:134455387..134455397,-p@chr4:134455387..134455397
-
Hg19::chr4:134455464..134455466,-p@chr4:134455464..134455466
-
Hg19::chr4:152546414..152546423,-p@chr4:152546414..152546423
-
Hg19::chr4:152550830..152550849,+p@chr4:152550830..152550849
+
Hg19::chr4:16728994..16729009,+p@chr4:16728994..16729009
+
Hg19::chr4:16729019..16729026,+p@chr4:16729019..16729026
+
Hg19::chr4:169995417..169995430,-p@chr4:169995417..169995430
-
Hg19::chr4:175133586..175133590,-p@chr4:175133586..175133590
-
Hg19::chr4:175135641..175135643,-p@chr4:175135641..175135643
-
Hg19::chr4:187604556..187604566,-p@chr4:187604556..187604566
-
Hg19::chr4:187812086..187812091,+p1@ENST00000507644
Hg19::chr4:187813673..187813681,+p@chr4:187813673..187813681
+
Hg19::chr4:65890078..65890091,-p@chr4:65890078..65890091
-
Hg19::chr4:65890130..65890142,-p@chr4:65890130..65890142
-
Hg19::chr4:65890174..65890177,-p@chr4:65890174..65890177
-
Hg19::chr4:71457970..71457974,+p1@AMBN
Hg19::chr4:79258891..79258912,+p@chr4:79258891..79258912
+
Hg19::chr4:80365166..80365171,-p@chr4:80365166..80365171
-
Hg19::chr4:81139161..81139177,-p@chr4:81139161..81139177
-
Hg19::chr4:81139299..81139316,+p@chr4:81139299..81139316
+
Hg19::chr4:81139386..81139412,+p@chr4:81139386..81139412
+
Hg19::chr4:90800713..90800718,+p17@MMRN1
Hg19::chr5:130341721..130341741,-p@chr5:130341721..130341741
-
Hg19::chr5:140367838..140367863,+p@chr5:140367838..140367863
+
Hg19::chr5:27727444..27727477,-p@chr5:27727444..27727477
-
Hg19::chr5:55759917..55759924,-p@chr5:55759917..55759924
-
Hg19::chr5:55759927..55759937,-p@chr5:55759927..55759937
-
Hg19::chr5:55760015..55760022,-p@chr5:55760015..55760022
-
Hg19::chr5:85119348..85119383,-p@chr5:85119348..85119383
-
Hg19::chr5:91905833..91905841,+p@chr5:91905833..91905841
+
Hg19::chr6:112668524..112668534,+p1@RFPL4B
Hg19::chr6:130760563..130760587,+p@chr6:130760563..130760587
+
Hg19::chr6:155776949..155776953,-p3@NOX3
Hg19::chr6:155776966..155776979,-p1@NOX3
Hg19::chr6:37475109..37475148,+p1@ENST00000373404
Hg19::chr6:44144302..44144307,+p5@CAPN11
Hg19::chr6:44144336..44144350,+p2@CAPN11
Hg19::chr6:44149125..44149136,+p@chr6:44149125..44149136
+
Hg19::chr6:79924920..79924970,-p@chr6:79924920..79924970
-
Hg19::chr7:115890213..115890234,+p19@TES
Hg19::chr7:115890251..115890259,+p33@TES
Hg19::chr7:115890264..115890281,+p14@TES
Hg19::chr7:115890310..115890317,+p40@TES
Hg19::chr7:115890330..115890335,+p42@TES
Hg19::chr7:130068212..130068237,-p@chr7:130068212..130068237
-
Hg19::chr7:130134563..130134573,+p@chr7:130134563..130134573
+
Hg19::chr7:130135180..130135185,+p@chr7:130135180..130135185
+
Hg19::chr7:130135190..130135198,+p@chr7:130135190..130135198
+
Hg19::chr7:135821982..135821990,+p@chr7:135821982..135821990
+
Hg19::chr7:144570766..144570771,+p@chr7:144570766..144570771
+
Hg19::chr7:150069666..150069674,-p1@ENST00000488310
Hg19::chr7:20784885..20784893,+p@chr7:20784885..20784893
+
Hg19::chr7:28964049..28964083,-p@chr7:28964049..28964083
-
Hg19::chr7:37070441..37070454,-p@chr7:37070441..37070454
-
Hg19::chr7:37070455..37070469,-p@chr7:37070455..37070469
-
Hg19::chr7:81093571..81093579,-p@chr7:81093571..81093579
-
Hg19::chr7:93472155..93472164,-p@chr7:93472155..93472164
-
Hg19::chr8:112834905..112834911,-p@chr8:112834905..112834911
-
Hg19::chr8:11536745..11536750,+p@chr8:11536745..11536750
+
Hg19::chr8:23340250..23340279,+p@chr8:23340250..23340279
+
Hg19::chr8:58658640..58658642,+p3@ENST00000518934
p3@uc003xti.1
Hg19::chr8:58658679..58658697,+p1@ENST00000518934
p1@uc003xti.1
Hg19::chr8:58658778..58658788,+p2@ENST00000518934
p2@uc003xti.1
Hg19::chr8:58660612..58660638,-p@chr8:58660612..58660638
-
Hg19::chr8:98458459..98458491,-p1@AK091342
Hg19::chr9:12636711..12636714,-p@chr9:12636711..12636714
-
Hg19::chr9:12636720..12636733,-p@chr9:12636720..12636733
-
Hg19::chr9:12636742..12636747,-p@chr9:12636742..12636747
-
Hg19::chr9:12651828..12651843,+p@chr9:12651828..12651843
+
Hg19::chr9:12685478..12685491,+p23@TYRP1
Hg19::chr9:12685502..12685507,+p43@TYRP1
Hg19::chr9:12685513..12685519,+p41@TYRP1
Hg19::chr9:14918266..14918270,-p@chr9:14918266..14918270
-
Hg19::chr9:14992508..14992514,+p@chr9:14992508..14992514
+
Hg19::chr9:75580427..75580442,-p@chr9:75580427..75580442
-
Hg19::chr9:75580478..75580479,-p@chr9:75580478..75580479
-
Hg19::chr9:75580502..75580515,-p@chr9:75580502..75580515
-
Hg19::chr9:75580541..75580558,-p@chr9:75580541..75580558
-
Hg19::chr9:9500545..9500549,+p@chr9:9500545..9500549
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0043169cation binding0.0280904135246401
GO:0046872metal ion binding0.0280904135246401
GO:0043167ion binding0.0280904135246401
GO:0009629response to gravity0.0327328388084305
GO:0043368positive T cell selection0.0381708408026043
GO:0045059positive thymic T cell selection0.0381708408026043
GO:0005507copper ion binding0.0381708408026043
GO:0004322ferroxidase activity0.0381708408026043
GO:0016724oxidoreductase activity, oxidizing metal ions, oxygen as acceptor0.0381708408026043
GO:0046873metal ion transmembrane transporter activity0.0381708408026043
GO:0045582positive regulation of T cell differentiation0.0381708408026043
GO:0015271outward rectifier potassium channel activity0.0381708408026043
GO:0045061thymic T cell selection0.0381708408026043
GO:0042438melanin biosynthetic process0.0381708408026043
GO:0033162melanosome membrane0.0381708408026043
GO:0030345structural constituent of tooth enamel0.0381708408026043
GO:0006583melanin biosynthetic process from tyrosine0.0381708408026043
GO:0045009chitosome0.0381708408026043
GO:0045621positive regulation of lymphocyte differentiation0.0381708408026043
GO:0016722oxidoreductase activity, oxidizing metal ions0.0381708408026043
GO:0006582melanin metabolic process0.0381708408026043
GO:0030021extracellular matrix structural constituent conferring compression resistance0.0381708408026043
GO:0001659thermoregulation0.0381708408026043
GO:0006725aromatic compound metabolic process0.0381708408026043
GO:0030001metal ion transport0.0402243618257222
GO:0006878cellular copper ion homeostasis0.0402243618257222
GO:0045058T cell selection0.0420108187206105
GO:0033077T cell differentiation in the thymus0.0420108187206105
GO:0045580regulation of T cell differentiation0.0450591316585281
GO:0016491oxidoreductase activity0.0458313927922714
GO:0055070copper ion homeostasis0.0458313927922714
GO:0004497monooxygenase activity0.0458313927922714
GO:0042101T cell receptor complex0.0474959343205725



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism5.68e-25115
central nervous system2.17e-1882
regional part of nervous system1.93e-1694
nervous system1.93e-1694
neural tube2.65e-1657
neural rod2.65e-1657
future spinal cord2.65e-1657
neural keel2.65e-1657
regional part of brain4.84e-1559
regional part of forebrain4.99e-1541
forebrain4.99e-1541
future forebrain4.99e-1541
brain8.70e-1569
future brain8.70e-1569
anterior neural tube2.41e-1442
neurectoderm9.10e-1490
neural plate7.92e-1386
presumptive neural plate7.92e-1386
telencephalon2.62e-1234
gray matter2.75e-1234
brain grey matter2.75e-1234
regional part of telencephalon6.05e-1233
cerebral hemisphere1.38e-1132
regional part of cerebral cortex8.21e-1122
neocortex1.11e-0920
cerebral cortex2.22e-0825
pallium2.22e-0825
pre-chordal neural plate4.47e-0861
ectoderm2.42e-07173
presumptive ectoderm2.42e-07173
anterior region of body4.87e-07129
craniocervical region4.87e-07129


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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