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Coexpression cluster:C994

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Full id: C994_adipose_colon_hairy_mature_amygdala_CD14_heart



Phase1 CAGE Peaks

Hg19::chr11:60094723..60094733,+p@chr11:60094723..60094733
+
Hg19::chr17:75126150..75126157,+p@chr17:75126150..75126157
+
Hg19::chr17:75126159..75126191,+p@chr17:75126159..75126191
+
Hg19::chr18:6997865..6997892,-p@chr18:6997865..6997892
-
Hg19::chr2:7118809..7118812,+p8@RNF144A
Hg19::chr3:114790272..114790294,-p34@ZBTB20
Hg19::chr5:41181741..41181743,-p@chr5:41181741..41181743
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Hg19::chr8:120710465..120710486,-p@chr8:120710465..120710486
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.44e-48115
neural tube3.65e-1957
neural rod3.65e-1957
future spinal cord3.65e-1957
neural keel3.65e-1957
central nervous system1.06e-1882
regional part of brain2.95e-1759
brain9.11e-1769
future brain9.11e-1769
anterior neural tube2.61e-1642
regional part of nervous system4.53e-1694
nervous system4.53e-1694
regional part of forebrain2.06e-1541
forebrain2.06e-1541
future forebrain2.06e-1541
telencephalon2.03e-1434
cerebral hemisphere2.27e-1432
regional part of telencephalon9.17e-1433
gray matter1.12e-1334
brain grey matter1.12e-1334
neural plate1.16e-1386
presumptive neural plate1.16e-1386
neurectoderm4.28e-1390
cerebral cortex5.28e-0925
pallium5.28e-0925
regional part of cerebral cortex5.78e-0922
pre-chordal neural plate7.34e-0961
anatomical cluster9.64e-09286
anatomical conduit1.31e-08241
anatomical system1.57e-08625
anterior region of body1.67e-08129
craniocervical region1.67e-08129
anatomical group1.95e-08626
multi-cellular organism1.99e-08659
tube2.32e-08194
embryo9.26e-08612
neocortex9.39e-0820
organ1.03e-07511
embryonic structure1.20e-07605
developing anatomical structure1.20e-07605
head1.47e-07123
germ layer2.42e-07604
embryonic tissue2.42e-07604
presumptive structure2.42e-07604
epiblast (generic)2.42e-07604
compound organ3.31e-0769
cell layer5.17e-07312
epithelium8.57e-07309
ectoderm-derived structure9.08e-07169


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.