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Coexpression cluster:C755

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Full id: C755_cerebellum_parietal_temporal_occipital_duodenum_brain_hippocampus



Phase1 CAGE Peaks

Hg19::chr14:23982181..23982193,-p@chr14:23982181..23982193
-
Hg19::chr17:2679600..2679618,+p@chr17:2679600..2679618
+
Hg19::chr19:42817494..42817510,+p5@TMEM145
Hg19::chr1:42384322..42384336,-p5@HIVEP3
Hg19::chr5:87979375..87979388,-p@chr5:87979375..87979388
-
Hg19::chr5:87980660..87980676,-p8@LINC00461
Hg19::chr5:87980761..87980821,-p4@LINC00461
Hg19::chr7:82753269..82753271,-p@chr7:82753269..82753271
-
Hg19::chr8:10192782..10192787,+p@chr8:10192782..10192787
+
Hg19::chr8:85114625..85114629,+p@chr8:85114625..85114629
+
Hg19::chr8:9970823..9970828,+p@chr8:9970823..9970828
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neural cell8.05e-0725
Uber Anatomy
Ontology termp-valuen
central nervous system3.68e-3982
regional part of nervous system2.84e-3794
nervous system2.84e-3794
neural tube2.93e-3657
neural rod2.93e-3657
future spinal cord2.93e-3657
neural keel2.93e-3657
regional part of brain6.82e-3359
brain1.10e-3269
future brain1.10e-3269
neurectoderm2.65e-2790
regional part of forebrain7.65e-2741
forebrain7.65e-2741
future forebrain7.65e-2741
anterior neural tube9.13e-2742
neural plate1.51e-2686
presumptive neural plate1.51e-2686
adult organism4.66e-24115
gray matter1.16e-2334
brain grey matter1.16e-2334
telencephalon1.20e-2334
regional part of telencephalon5.62e-2333
cerebral hemisphere1.56e-2232
cerebral cortex3.33e-1825
pallium3.33e-1825
ectoderm4.35e-18173
presumptive ectoderm4.35e-18173
pre-chordal neural plate9.80e-1861
ectoderm-derived structure2.64e-17169
regional part of cerebral cortex2.00e-1622
neocortex4.08e-1520
anterior region of body7.96e-15129
craniocervical region7.96e-15129
head3.53e-14123
posterior neural tube1.80e-1015
chordal neural plate1.80e-1015
segmental subdivision of nervous system2.70e-0913
segmental subdivision of hindbrain8.58e-0912
hindbrain8.58e-0912
presumptive hindbrain8.58e-0912
basal ganglion4.93e-079
nuclear complex of neuraxis4.93e-079
aggregate regional part of brain4.93e-079
collection of basal ganglia4.93e-079
cerebral subcortex4.93e-079
regional part of metencephalon5.38e-079
metencephalon5.38e-079
future metencephalon5.38e-079
nucleus of brain6.67e-079
neural nucleus6.67e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.