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Coexpression cluster:C3267

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Full id: C3267_temporal_parietal_duodenum_Chondrocyte_colon_occipital_Neural



Phase1 CAGE Peaks

Hg19::chr12:24097201..24097216,-p10@SOX5
Hg19::chr12:24097236..24097256,-p9@SOX5
Hg19::chr12:24102576..24102623,-p2@SOX5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.10e-4557
neural rod1.10e-4557
future spinal cord1.10e-4557
neural keel1.10e-4557
central nervous system6.31e-4282
regional part of forebrain1.14e-4041
forebrain1.14e-4041
future forebrain1.14e-4041
anterior neural tube2.76e-3942
regional part of nervous system3.26e-3994
nervous system3.26e-3994
regional part of brain6.27e-3959
neural plate1.41e-3686
presumptive neural plate1.41e-3686
brain1.40e-3569
future brain1.40e-3569
adult organism1.67e-35115
neurectoderm2.23e-3590
telencephalon1.51e-3434
gray matter2.21e-3434
brain grey matter2.21e-3434
regional part of telencephalon1.79e-3333
cerebral hemisphere6.34e-3332
pre-chordal neural plate1.88e-2961
cerebral cortex1.56e-2625
pallium1.56e-2625
regional part of cerebral cortex1.18e-2322
ectoderm-derived structure4.39e-23169
ectoderm8.22e-23173
presumptive ectoderm8.22e-23173
neocortex1.06e-2120
head1.27e-21123
anterior region of body3.13e-21129
craniocervical region3.13e-21129
tube1.39e-12194
anatomical conduit5.57e-11241
anatomical cluster7.25e-11286
multi-tissue structure2.19e-10347
basal ganglion1.22e-099
nuclear complex of neuraxis1.22e-099
aggregate regional part of brain1.22e-099
collection of basal ganglia1.22e-099
cerebral subcortex1.22e-099
temporal lobe2.18e-097
nucleus of brain3.13e-099
neural nucleus3.13e-099
epithelium3.31e-09309
cell layer7.44e-09312
posterior neural tube4.35e-0815
chordal neural plate4.35e-0815
organism subdivision9.46e-08365
embryo9.90e-08612
telencephalic nucleus1.46e-077
gyrus1.71e-076
organ1.76e-07511
diencephalon1.91e-077
future diencephalon1.91e-077


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.