UBERON:0001285
From FANTOM5_SSTAR
| Name: | nephron | ||
|---|---|---|---|
| Definition: | "The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]" [PMID:9268568, Wikipedia:Nephron] | ||
| Xrefs: |
| ||
| Synonyms: |
"mature nephron" NARROW [EMAPA:28491] "nephroneum" RELATED LATIN [Wikipedia:Nephron] "tubulus renalis" RELATED LATIN [Wikipedia:Nephron] | ||
| Comments: | Editor note: kidney terms require review for cross-vertebrate compatibility and developmental relationships. Taxon notes: In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)[GO Kidney] | ||
| Alt_id: | UBERON:FMA_17640-MA_0000375-XAO_0000145 | ||
| Subset: |
uberon_slim vertebrate_core |
Gray1128.png]
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Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0000064(organ part),UBERON:0006554(urinary system structure) |
|---|---|
| develops_from: | UBERON:0004208(nephrogenic mesenchyme) |
| part_of: | UBERON:0007684(uriniferous tubule) |
Children
| part of: | UBERON:0001229 (renal corpuscle),UBERON:0001231 (nephron tubule),UBERON:0004198 (comma-shaped body),UBERON:0004211 (nephron epithelium),CL:1000449 (epithelial cell of nephron) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11514-119H2 (Renal Glomerular Endothelial Cells, donor1)
- 11515-119H3 (Renal Proximal Tubular Epithelial Cell, donor1)
- 11516-119H4 (Renal Cortical Epithelial Cells, donor1)
- 11517-119H5 (Renal Epithelial Cells, donor1)
- 11518-119H6 (Renal Mesangial Cells, donor1)
- 11590-120G6 (Alveolar Epithelial Cells, donor2)
- 11594-120H1 (Renal Glomerular Endothelial Cells, donor2)
- 11595-120H2 (Renal Proximal Tubular Epithelial Cell, donor2)
- 11596-120H3 (Renal Cortical Epithelial Cells, donor2)
- 11597-120H4 (Renal Epithelial Cells, donor2)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001285 (nephron), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.05e-87 | FFCP PHASE2:Hg19::chr2:693380..693398,+#_91104e4ca3c3d7c7102b42bb878e8259 | p@chr2:693380..693398, + |
| 1.05e-87 | FFCP PHASE1:Hg19::chr2:693380..693398,+#_91104e4ca3c3d7c7102b42bb878e8259 | p@chr2:693380..693398, + |
| 1.72e-83 | FFCP PHASE1:Hg19::chr15:66420804..66420837,-#_b5b2e2d2fb57d3054ba5aced5e02e4bd | p4@MEGF11 |
| 1.72e-83 | FFCP PHASE2:Hg19::chr15:66420804..66420837,-#_b5b2e2d2fb57d3054ba5aced5e02e4bd | p4@MEGF11 |
| 2.2e-74 | FFCP PHASE1:Hg19::chr7:27219833..27219845,-#_99d8a9510e3c52d550fc3ec3dda3fc74 | p7@HOXA10 |
| 2.2e-74 | FFCP PHASE2:Hg19::chr7:27219833..27219845,-#_99d8a9510e3c52d550fc3ec3dda3fc74 | p7@HOXA10 |
| 7.63e-66 | FFCP PHASE2:Hg19::chr1:1100457..1100470,+#_ec75065b9a1434123363139731bf31b1 | p@chr1:1100457..1100470, + |
| 7.63e-66 | FFCP PHASE1:Hg19::chr1:1100457..1100470,+#_ec75065b9a1434123363139731bf31b1 | p@chr1:1100457..1100470, + |
| 6.44e-62 | FFCP PHASE1:Hg19::chr10:102495147..102495159,+#_624776bde443b07dccdabcf31960a843 | p4@PAX2 |
| 6.44e-62 | FFCP PHASE2:Hg19::chr10:102495147..102495159,+#_624776bde443b07dccdabcf31960a843 | p4@PAX2 |
| 5.84e-60 | FFCP PHASE2:Hg19::chr18:3456189..3456200,+#_9c72f02497cbbd6ae26f7d241132bc4e | p@chr18:3456189..3456200, + |
| 5.84e-60 | FFCP PHASE1:Hg19::chr18:3456189..3456200,+#_9c72f02497cbbd6ae26f7d241132bc4e | p@chr18:3456189..3456200, + |
| 6.18e-60 | FFCP PHASE1:Hg19::chr10:102505954..102505973,+#_9a25380f7e1ac6d31f65143f0648766e | p3@PAX2 |
| 6.18e-60 | FFCP PHASE2:Hg19::chr10:102505954..102505973,+#_9a25380f7e1ac6d31f65143f0648766e | p3@PAX2 |
| 4.45e-59 | FFCP PHASE1:Hg19::chr20:6034607..6034616,-#_45491facab4bf489cb14238358ec4e03 | p6@LRRN4 |
| 4.45e-59 | FFCP PHASE2:Hg19::chr20:6034607..6034616,-#_45491facab4bf489cb14238358ec4e03 | p6@LRRN4 |
| 3.49e-58 | FFCP PHASE1:Hg19::chr5:74244100..74244117,+#_6a3691bd9eb6b529ab35c4148982995d | p@chr5:74244100..74244117, + |
| 3.49e-58 | FFCP PHASE2:Hg19::chr5:74244100..74244117,+#_6a3691bd9eb6b529ab35c4148982995d | p@chr5:74244100..74244117, + |
| 3.91e-56 | FFCP PHASE1:Hg19::chr20:6033532..6033548,-#_1758b8e6cb4065fcd05f19814237d389 | p2@AB527789 |
| 3.91e-56 | FFCP PHASE2:Hg19::chr20:6033532..6033548,-#_1758b8e6cb4065fcd05f19814237d389 | p2@AB527789 |
| 3.83e-55 | FFCP PHASE1:Hg19::chr16:86604624..86604648,+#_48660965d078edd38a9902276d182ccd | p@chr16:86604624..86604648, + |
| 3.83e-55 | FFCP PHASE2:Hg19::chr16:86604624..86604648,+#_48660965d078edd38a9902276d182ccd | p@chr16:86604624..86604648, + |
| 3.51e-54 | FFCP PHASE1:Hg19::chr16:86768403..86768437,+#_70be711f5fe544aaf2b7f3a7a143ae25 | p@chr16:86768403..86768437, + |
| 3.51e-54 | FFCP PHASE2:Hg19::chr16:86768403..86768437,+#_70be711f5fe544aaf2b7f3a7a143ae25 | p@chr16:86768403..86768437, + |
| 6.09e-53 | FFCP PHASE1:Hg19::chr16:3068288..3068312,-#_194ce24f9849aff0659bee8bdb323a6f | p2@CLDN6 |
| 6.09e-53 | FFCP PHASE2:Hg19::chr16:3068288..3068312,-#_194ce24f9849aff0659bee8bdb323a6f | p2@CLDN6 |
| 2.79e-52 | FFCP PHASE1:Hg19::chr1:81001398..81001426,+#_616ee0cf2b83aaa29e9fcf55ae0305fc | p1@ENST00000418041, p1@ENST00000443104 |
| 2.79e-52 | FFCP PHASE2:Hg19::chr1:81001398..81001426,+#_616ee0cf2b83aaa29e9fcf55ae0305fc | p1@ENST00000418041, p1@ENST00000443104 |
| 1.61e-50 | FFCP PHASE2:Hg19::chr7:7606139..7606151,-#_d408aa45c44538d49e6641054066da8e | p@chr7:7606139..7606151, - |
| 1.61e-50 | FFCP PHASE1:Hg19::chr7:7606139..7606151,-#_d408aa45c44538d49e6641054066da8e | p@chr7:7606139..7606151, - |
| 1.96e-50 | FFCP PHASE1:Hg19::chr17:36104873..36104903,-#_4ba3a7b979c4c14dc438923985afda62 | p3@HNF1B |
| 1.96e-50 | FFCP PHASE2:Hg19::chr17:36104873..36104903,-#_4ba3a7b979c4c14dc438923985afda62 | p3@HNF1B |
| 1.73e-49 | FFCP PHASE1:Hg19::chr7:140227349..140227360,-#_0fb2a0d97c5d520c64b28446da1e8c90 | p@chr7:140227349..140227360, - |
| 1.73e-49 | FFCP PHASE2:Hg19::chr7:140227349..140227360,-#_0fb2a0d97c5d520c64b28446da1e8c90 | p@chr7:140227349..140227360, - |
| 2.61e-49 | FFCP PHASE1:Hg19::chr7:27219754..27219759,-#_ebb10eedbd44005f4270b7f00fa1b612 | p16@HOXA10 |
| 2.61e-49 | FFCP PHASE2:Hg19::chr7:27219754..27219759,-#_ebb10eedbd44005f4270b7f00fa1b612 | p16@HOXA10 |
| 3.13e-49 | FFCP PHASE2:Hg19::chr21:41029235..41029269,+#_fdfda826e487832658ee53c541205b2e | p2@B3GALT5 |
| 3.13e-49 | FFCP PHASE1:Hg19::chr21:41029235..41029269,+#_fdfda826e487832658ee53c541205b2e | p2@B3GALT5 |
| 4.07e-49 | FFCP PHASE2:Hg19::chr9:133986782..133986794,+#_e9ed3a58bf3bbe1890b3a8df9d595415 | p4@AIF1L |
| 4.07e-49 | FFCP PHASE1:Hg19::chr9:133986782..133986794,+#_e9ed3a58bf3bbe1890b3a8df9d595415 | p4@AIF1L |
| 1.12e-47 | FFCP PHASE1:Hg19::chr7:140227303..140227330,-#_fb7b451c69dbbd9d981637b3afd98694 | p@chr7:140227303..140227330, - |
| 1.12e-47 | FFCP PHASE2:Hg19::chr7:140227303..140227330,-#_fb7b451c69dbbd9d981637b3afd98694 | p@chr7:140227303..140227330, - |
| 1.23e-44 | FFCP PHASE1:Hg19::chr20:6034576..6034592,-#_666bc6014b1f1800ae865b404fea5de4 | p3@LRRN4 |
| 1.23e-44 | FFCP PHASE2:Hg19::chr20:6034576..6034592,-#_666bc6014b1f1800ae865b404fea5de4 | p3@LRRN4 |
| 3.62e-44 | FFCP PHASE2:Hg19::chr21:46826248..46826282,-#_0b849ea9dbfa06a4601fdc12a7213061 | p@chr21:46826248..46826282, - |
| 3.62e-44 | FFCP PHASE1:Hg19::chr21:46826248..46826282,-#_0b849ea9dbfa06a4601fdc12a7213061 | p@chr21:46826248..46826282, - |
| 3.06e-43 | FFCP PHASE1:Hg19::chr20:6034672..6034714,-#_1aaad7fbbe84449be0ad9d5edd34b2b6 | p2@LRRN4 |
| 3.06e-43 | FFCP PHASE2:Hg19::chr20:6034672..6034714,-#_1aaad7fbbe84449be0ad9d5edd34b2b6 | p2@LRRN4 |
| 1.81e-42 | FFCP PHASE1:Hg19::chr15:85403302..85403304,+#_f88ad95377422916f6645354940a7ee9 | p@chr15:85403302..85403304, + |
| 1.81e-42 | FFCP PHASE2:Hg19::chr15:85403302..85403304,+#_f88ad95377422916f6645354940a7ee9 | p@chr15:85403302..85403304, + |
| 1.82e-42 | FFCP PHASE2:Hg19::chr7:98453821..98453843,-#_425e0ce939b3123aed923eae0543b164 | p@chr7:98453821..98453843, - |
| 1.82e-42 | FFCP PHASE1:Hg19::chr7:98453821..98453843,-#_425e0ce939b3123aed923eae0543b164 | p@chr7:98453821..98453843, - |
| 2.77e-42 | FFCP PHASE1:Hg19::chr20:6034598..6034603,-#_ae3bf0415ac0ebb2205545db74a148ec | p7@LRRN4 |
| 2.77e-42 | FFCP PHASE2:Hg19::chr20:6034598..6034603,-#_ae3bf0415ac0ebb2205545db74a148ec | p7@LRRN4 |
| 7.5e-42 | FFCP PHASE1:Hg19::chr10:102505493..102505546,+#_030f440f61bf2409587e4858f869b3e5 | p2@PAX2 |
| 7.5e-42 | FFCP PHASE2:Hg19::chr10:102505493..102505546,+#_030f440f61bf2409587e4858f869b3e5 | p2@PAX2 |
| 3.59e-41 | FFCP PHASE2:Hg19::chr9:71735910..71735923,+#_84f22180c856e003aa3ebb0f69a79b9d | p16@TJP2 |
| 3.59e-41 | FFCP PHASE1:Hg19::chr9:71735910..71735923,+#_84f22180c856e003aa3ebb0f69a79b9d | p16@TJP2 |
| 9.39e-41 | FFCP PHASE2:Hg19::chr1:94713418..94713436,+#_2b21f5cda511ef37bf676dc67fba6bde | p1@ENST00000413103 |
| 9.39e-41 | FFCP PHASE1:Hg19::chr1:94713418..94713436,+#_2b21f5cda511ef37bf676dc67fba6bde | p1@ENST00000413103 |
| 1.7e-40 | FFCP PHASE1:Hg19::chr20:6034828..6034857,-#_ad22dbc1b161a6eaaee07b070f8bc1db | p5@LRRN4 |
| 1.7e-40 | FFCP PHASE2:Hg19::chr20:6034828..6034857,-#_ad22dbc1b161a6eaaee07b070f8bc1db | p5@LRRN4 |
| 2.9e-40 | FFCP PHASE2:Hg19::chr1:20465872..20465881,+#_b5dabb8f1e78852f0ae4659568a975b1 | p2@PLA2G2F |
| 2.9e-40 | FFCP PHASE1:Hg19::chr1:20465872..20465881,+#_b5dabb8f1e78852f0ae4659568a975b1 | p2@PLA2G2F |
| 8.58e-40 | FFCP PHASE2:Hg19::chr9:133986807..133986821,+#_5bea74bba07f8d3313a4e58c7176b667 | p3@AIF1L |
| 8.58e-40 | FFCP PHASE1:Hg19::chr9:133986807..133986821,+#_5bea74bba07f8d3313a4e58c7176b667 | p3@AIF1L |
| 1.21e-39 | FFCP PHASE1:Hg19::chr2:31361432..31361442,-#_6c4c1ae95bb76c00a74561c622527606 | p6@GALNT14 |
| 1.21e-39 | FFCP PHASE2:Hg19::chr2:31361432..31361442,-#_6c4c1ae95bb76c00a74561c622527606 | p6@GALNT14 |
| 3.08e-39 | FFCP PHASE1:Hg19::chr20:6033120..6033128,-#_74baf68b82f5fbb44ba981f1902f76f5 | p4@AB527789 |
| 3.08e-39 | FFCP PHASE2:Hg19::chr20:6033120..6033128,-#_74baf68b82f5fbb44ba981f1902f76f5 | p4@AB527789 |
| 7.42e-37 | FFCP PHASE1:Hg19::chr6:24358114..24358125,-#_55911a188929b8f82843f5918a0647c8 | p4@DCDC2 |
| 7.42e-37 | FFCP PHASE2:Hg19::chr6:24358114..24358125,-#_55911a188929b8f82843f5918a0647c8 | p4@DCDC2 |
| 1.29e-36 | FFCP PHASE1:Hg19::chr2:693362..693373,+#_cb113613717e4a87079ce2ce830c8bb9 | p@chr2:693362..693373, + |
| 1.29e-36 | FFCP PHASE2:Hg19::chr2:693362..693373,+#_cb113613717e4a87079ce2ce830c8bb9 | p@chr2:693362..693373, + |
| 1.36e-36 | FFCP PHASE2:Hg19::chr2:177016336..177016350,+#_191e41fade9304f8be80092ae9e5ab1c | p1@HOXD4 |
| 1.36e-36 | FFCP PHASE1:Hg19::chr2:177016336..177016350,+#_191e41fade9304f8be80092ae9e5ab1c | p1@HOXD4 |
| 6.21e-36 | FFCP PHASE2:Hg19::chr2:176982078..176982095,+#_f46120476a9c3386d5abd854f4370a39 | p@chr2:176982078..176982095, + |
| 6.21e-36 | FFCP PHASE1:Hg19::chr2:176982078..176982095,+#_f46120476a9c3386d5abd854f4370a39 | p@chr2:176982078..176982095, + |
| 2.64e-35 | FFCP PHASE1:Hg19::chr20:6033140..6033181,-#_8065f0e90b4dbf0e25e4965554ba3f4e | p1@AB527789 |
| 2.64e-35 | FFCP PHASE2:Hg19::chr20:6033140..6033181,-#_8065f0e90b4dbf0e25e4965554ba3f4e | p1@AB527789 |
| 3.85e-35 | FFCP PHASE2:Hg19::chr2:108994466..108994485,+#_32ffc6addc91f50be904ed482fd3e750 | p3@SULT1C4 |
| 3.85e-35 | FFCP PHASE1:Hg19::chr2:108994466..108994485,+#_32ffc6addc91f50be904ed482fd3e750 | p3@SULT1C4 |
| 8.14e-35 | FFCP PHASE1:Hg19::chr18:43405633..43405645,+#_92c54e20fa936d6063019d6f002f6d38 | p4@SIGLEC15 |
| 8.14e-35 | FFCP PHASE2:Hg19::chr18:43405633..43405645,+#_92c54e20fa936d6063019d6f002f6d38 | p4@SIGLEC15 |
| 1.65e-34 | FFCP PHASE1:Hg19::chr10:91043420..91043437,+#_4bf2837b8e2dec77bd2d0e39f5edd13b | p1@ENST00000444849 |
| 1.65e-34 | FFCP PHASE2:Hg19::chr10:91043420..91043437,+#_4bf2837b8e2dec77bd2d0e39f5edd13b | p1@ENST00000444849 |
| 1.14e-33 | FFCP PHASE1:Hg19::chr17:171147..171161,+#_230e2f36ce9ced67c18cc1ee7cce272d | p@chr17:171147..171161, + |
| 1.14e-33 | FFCP PHASE2:Hg19::chr17:171147..171161,+#_230e2f36ce9ced67c18cc1ee7cce272d | p@chr17:171147..171161, + |
| 1.52e-33 | FFCP PHASE1:Hg19::chr14:57960456..57960478,-#_7c5d85da28bec35a4b698f368a8920c0 | p2@C14orf105 |
| 1.52e-33 | FFCP PHASE2:Hg19::chr14:57960456..57960478,-#_7c5d85da28bec35a4b698f368a8920c0 | p2@C14orf105 |
| 1.8e-33 | FFCP PHASE1:Hg19::chr2:31361543..31361564,-#_85222359e6f791afd7571f9f7d5a0098 | p5@GALNT14 |
| 1.8e-33 | FFCP PHASE2:Hg19::chr2:31361543..31361564,-#_85222359e6f791afd7571f9f7d5a0098 | p5@GALNT14 |
| 2.35e-33 | FFCP PHASE2:Hg19::chr3:190105935..190105966,+#_c1686d335efd237ddc23983cbe7e3484 | p1@CLDN16 |
| 2.35e-33 | FFCP PHASE1:Hg19::chr3:190105935..190105966,+#_c1686d335efd237ddc23983cbe7e3484 | p1@CLDN16 |
| 4.12e-33 | FFCP PHASE1:Hg19::chr17:36065029..36065045,-#_494d6a8330b9b205293381207d162a49 | p@chr17:36065029..36065045, - |
| 4.12e-33 | FFCP PHASE2:Hg19::chr17:36065029..36065045,-#_494d6a8330b9b205293381207d162a49 | p@chr17:36065029..36065045, - |
| 8.12e-33 | FFCP PHASE1:Hg19::chr17:35293950..35293973,-#_7b02b5fedfb37b3da37f1061180822a5 | p1@ENST00000528383, p1@ENST00000529264, p1@ENST00000532387 |
| 8.12e-33 | FFCP PHASE2:Hg19::chr17:35293950..35293973,-#_7b02b5fedfb37b3da37f1061180822a5 | p1@ENST00000528383, p1@ENST00000529264, p1@ENST00000532387 |
| 1.25e-32 | FFCP PHASE2:Hg19::chr22:30653574..30653606,-#_ce4bbb0660fc3579ee75a41e739a08eb | p@chr22:30653574..30653606, - |
| 1.25e-32 | FFCP PHASE1:Hg19::chr22:30653574..30653606,-#_ce4bbb0660fc3579ee75a41e739a08eb | p@chr22:30653574..30653606, - |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Functional unit of the kidney that filters waste.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
