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UBERON:0000013

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Name:sympathetic nervous system
Definition:"The Sympathetic Nervous System (SNS) is a branch of the autonomic nervous system along with the enteric nervous system and parasympathetic nervous system. It is always active at a basal level (called sympathetic tone) and becomes more active during times of stress. Its actions during the stress response comprise the fight-or-flight response [Wikipedia]. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." [Wikipedia:Sympathetic_nervous_system]
Xrefs:
links:

AAO:0010487
BTO:0001832
EFO:0000893
EHDAA2:0001971
EHDAA:3769
EMAPA:16985
FMA:9906
GAID:710
[ Gray838.png Gray838.png]
[ 200px-Gray838.png 200px-Gray838.png]
MA:0000225
MESH:A.08.800.050.800
MIAA:0000100
ncithesaurus:Sympathetic_Nervous_System
NIF_GrossAnatomy:birnlex_2516
SCTID:362484004
TAO:0001576
VHOG:0000384

ZFA:0001576
Synonyms: "pars sympathica divisionis autonomici systematis nervosi" EXACT [FMA:9906, FMA:TA]
"pars sympathica divisionis autonomici systematis nervosi" RELATED LATIN [Wikipedia:Sympathetic_nervous_system]
"sympathetic nervous system" EXACT []
"sympathetic part of autonomic division of nervous system" EXACT []
Comments:Development notes: has developmental contribution from NC in verteberates (UBERONREF:0000002)
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002410(autonomic nervous system)



Children

derives from:FF:0011144 (mouse neurospheres - sympathetic neuron derived sample),FF:0100932 (neuroblastoma cell line sample)
part of:FF:0011144 (mouse neurospheres - sympathetic neuron derived sample),FF:11804-124D4 (neurospheres - sympathetic neuron derived, biol_rep1),FF:11805-124D5 (neurospheres - sympathetic neuron derived, biol_rep2),FF:11806-124D6 (neurospheres - sympathetic neuron derived, biol_rep3)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000013 (sympathetic nervous system), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
7.76e-118FFCP PHASE2:Hg19::chr1:50569575..50569586,+#_7ec07f40886546a5f1f1097d848c8250p11@ELAVL4
7.76e-118FFCP PHASE1:Hg19::chr1:50569575..50569586,+#_7ec07f40886546a5f1f1097d848c8250p11@ELAVL4
7.76e-118FFCP PHASE1:Hg19::chr11:71952309..71952319,-#_7ec07f40886546a5f1f1097d848c8250p2@PHOX2A
7.76e-118FFCP PHASE2:Hg19::chr2:16081024..16081034,+#_7ec07f40886546a5f1f1097d848c8250p10@MYCN
7.76e-118FFCP PHASE2:Hg19::chr11:71952309..71952319,-#_7ec07f40886546a5f1f1097d848c8250p2@PHOX2A
7.76e-118FFCP PHASE2:Hg19::chr4:41859832..41859854,+#_7ec07f40886546a5f1f1097d848c8250p@chr4:41859832..41859854, +
7.76e-118FFCP PHASE1:Hg19::chr2:16081024..16081034,+#_7ec07f40886546a5f1f1097d848c8250p10@MYCN
7.76e-118FFCP PHASE2:Hg19::chr4:41884620..41884663,-#_7ec07f40886546a5f1f1097d848c8250p1@ENST00000504870
7.76e-118FFCP PHASE1:Hg19::chr4:41884620..41884663,-#_7ec07f40886546a5f1f1097d848c8250p1@ENST00000504870
7.76e-118FFCP PHASE1:Hg19::chr4:41859832..41859854,+#_7ec07f40886546a5f1f1097d848c8250p@chr4:41859832..41859854, +
7.76e-118FFCP PHASE2:Hg19::chr2:16082384..16082391,+#_7ec07f40886546a5f1f1097d848c8250p9@MYCN
7.76e-118FFCP PHASE1:Hg19::chr2:16082384..16082391,+#_7ec07f40886546a5f1f1097d848c8250p9@MYCN
5.18e-105FFCP PHASE2:Hg19::chr4:41750860..41750867,-#_acaccd53c50b042fd3dc67678cf1cde6p8@PHOX2B
5.18e-105FFCP PHASE1:Hg19::chr4:41750860..41750867,-#_acaccd53c50b042fd3dc67678cf1cde6p8@PHOX2B
6.77e-105FFCP PHASE2:Hg19::chr8:142878006..142878015,+#_5dc86e29328eda12601d0e14fe18c8f9p@chr8:142878006..142878015, +
6.77e-105FFCP PHASE1:Hg19::chr8:142878006..142878015,+#_5dc86e29328eda12601d0e14fe18c8f9p@chr8:142878006..142878015, +
6.64e-89FFCP PHASE1:Hg19::chr2:16082395..16082415,+#_4c79fa0308d857a41e7087c5496a367ap6@MYCN
6.64e-89FFCP PHASE2:Hg19::chr2:16082418..16082429,+#_4c79fa0308d857a41e7087c5496a367ap8@MYCN
6.64e-89FFCP PHASE1:Hg19::chr2:16082418..16082429,+#_4c79fa0308d857a41e7087c5496a367ap8@MYCN
6.64e-89FFCP PHASE2:Hg19::chr4:174440390..174440400,-#_4c79fa0308d857a41e7087c5496a367ap@chr4:174440390..174440400, -
6.64e-89FFCP PHASE2:Hg19::chr5:168271880..168271889,-#_4c79fa0308d857a41e7087c5496a367ap15@SLIT3
6.64e-89FFCP PHASE2:Hg19::chr2:74735290..74735299,-#_4c79fa0308d857a41e7087c5496a367ap11@PCGF1
6.64e-89FFCP PHASE1:Hg19::chr4:174440390..174440400,-#_4c79fa0308d857a41e7087c5496a367ap@chr4:174440390..174440400, -
6.64e-89FFCP PHASE1:Hg19::chr5:168271880..168271889,-#_4c79fa0308d857a41e7087c5496a367ap15@SLIT3
6.64e-89FFCP PHASE1:Hg19::chr2:74735290..74735299,-#_4c79fa0308d857a41e7087c5496a367ap11@PCGF1
6.64e-89FFCP PHASE2:Hg19::chr2:16082395..16082415,+#_4c79fa0308d857a41e7087c5496a367ap6@MYCN
8.98e-89FFCP PHASE2:Hg19::chr2:74735271..74735288,-#_865ccd7047434a984904ba08aa788a22p10@PCGF1
8.98e-89FFCP PHASE1:Hg19::chr2:74735271..74735288,-#_865ccd7047434a984904ba08aa788a22p10@PCGF1
8.98e-89FFCP PHASE1:Hg19::chr11:71952772..71952788,-#_865ccd7047434a984904ba08aa788a22p@chr11:71952772..71952788, -
8.98e-89FFCP PHASE2:Hg19::chr11:71952772..71952788,-#_865ccd7047434a984904ba08aa788a22p@chr11:71952772..71952788, -
1.21e-88FFCP PHASE2:Hg19::chr4:175257438..175257442,+#_6d1197d2b6aa39864600c653b6652167p@chr4:175257438..175257442, +
1.21e-88FFCP PHASE1:Hg19::chr4:175257438..175257442,+#_6d1197d2b6aa39864600c653b6652167p@chr4:175257438..175257442, +
2.12e-79FFCP PHASE2:Hg19::chr4:41750895..41750904,-#_916fef99c321b29738e8311edfdbe6d2p6@PHOX2B
2.12e-79FFCP PHASE1:Hg19::chr4:41750895..41750904,-#_916fef99c321b29738e8311edfdbe6d2p6@PHOX2B
3.49e-79FFCP PHASE1:Hg19::chr4:41875797..41875802,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:41875797..41875802, -
3.49e-79FFCP PHASE2:Hg19::chr5:168310338..168310348,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr5:168310338..168310348, -
3.49e-79FFCP PHASE1:Hg19::chr7:19185044..19185056,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:19185044..19185056, +
3.49e-79FFCP PHASE1:Hg19::chr4:174930547..174930558,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174930547..174930558, -
3.49e-79FFCP PHASE2:Hg19::chr7:19185475..19185487,-#_2bcf9c14bc230f53e06a71f014d6800dp1@FERD3L
3.49e-79FFCP PHASE2:Hg19::chr11:71955016..71955024,-#_2bcf9c14bc230f53e06a71f014d6800dp7@PHOX2A
3.49e-79FFCP PHASE2:Hg19::chr4:113870230..113870237,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:113870230..113870237, +
3.49e-79FFCP PHASE2:Hg19::chr18:77044132..77044175,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr18:77044132..77044175, +
3.49e-79FFCP PHASE1:Hg19::chr5:168310338..168310348,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr5:168310338..168310348, -
3.49e-79FFCP PHASE2:Hg19::chr7:19186529..19186536,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:19186529..19186536, +
3.49e-79FFCP PHASE2:Hg19::chr4:175041125..175041137,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:175041125..175041137, -
3.49e-79FFCP PHASE1:Hg19::chr17:74540293..74540300,+#_2bcf9c14bc230f53e06a71f014d6800dp15@PRCD
3.49e-79FFCP PHASE1:Hg19::chr7:19185475..19185487,-#_2bcf9c14bc230f53e06a71f014d6800dp1@FERD3L
3.49e-79FFCP PHASE2:Hg19::chr7:8276508..8276551,-#_2bcf9c14bc230f53e06a71f014d6800dp14@ICA1
3.49e-79FFCP PHASE1:Hg19::chr11:71952706..71952712,-#_2bcf9c14bc230f53e06a71f014d6800dp4@PHOX2A
3.49e-79FFCP PHASE2:Hg19::chr7:19185493..19185503,-#_2bcf9c14bc230f53e06a71f014d6800dp2@FERD3L
3.49e-79FFCP PHASE2:Hg19::chr4:174954376..174954399,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174954376..174954399, -
3.49e-79FFCP PHASE1:Hg19::chr4:113870230..113870237,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:113870230..113870237, +
3.49e-79FFCP PHASE1:Hg19::chr7:8276508..8276551,-#_2bcf9c14bc230f53e06a71f014d6800dp14@ICA1
3.49e-79FFCP PHASE2:Hg19::chr17:11389592..11389599,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr17:11389592..11389599, -
3.49e-79FFCP PHASE1:Hg19::chr7:19186529..19186536,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:19186529..19186536, +
3.49e-79FFCP PHASE1:Hg19::chr4:175041125..175041137,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:175041125..175041137, -
3.49e-79FFCP PHASE2:Hg19::chr7:8302002..8302015,-#_2bcf9c14bc230f53e06a71f014d6800dp10@ICA1
3.49e-79FFCP PHASE2:Hg19::chr4:175041762..175041777,-#_2bcf9c14bc230f53e06a71f014d6800dp2@ENST00000503140
3.49e-79FFCP PHASE1:Hg19::chr7:8302002..8302015,-#_2bcf9c14bc230f53e06a71f014d6800dp10@ICA1
3.49e-79FFCP PHASE2:Hg19::chr4:174930472..174930480,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174930472..174930480, -
3.49e-79FFCP PHASE2:Hg19::chr11:71952706..71952712,-#_2bcf9c14bc230f53e06a71f014d6800dp4@PHOX2A
3.49e-79FFCP PHASE1:Hg19::chr18:77044132..77044175,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr18:77044132..77044175, +
3.49e-79FFCP PHASE2:Hg19::chr5:16180927..16180934,-#_2bcf9c14bc230f53e06a71f014d6800dp7@MARCH11
3.49e-79FFCP PHASE2:Hg19::chr2:29728669..29728672,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:29728669..29728672, -
3.49e-79FFCP PHASE1:Hg19::chr17:11389592..11389599,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr17:11389592..11389599, -
3.49e-79FFCP PHASE2:Hg19::chr2:16082933..16082942,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:16082933..16082942, +
3.49e-79FFCP PHASE1:Hg19::chr7:19185493..19185503,-#_2bcf9c14bc230f53e06a71f014d6800dp2@FERD3L
3.49e-79FFCP PHASE1:Hg19::chr4:174954376..174954399,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174954376..174954399, -
3.49e-79FFCP PHASE2:Hg19::chr18:56886837..56886844,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr18:56886837..56886844, +
3.49e-79FFCP PHASE2:Hg19::chr7:8276855..8276873,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:8276855..8276873, +
3.49e-79FFCP PHASE1:Hg19::chr2:29728669..29728672,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:29728669..29728672, -
3.49e-79FFCP PHASE2:Hg19::chr7:19185559..19185569,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:19185559..19185569, -
3.49e-79FFCP PHASE1:Hg19::chr7:8276855..8276873,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:8276855..8276873, +
3.49e-79FFCP PHASE2:Hg19::chr2:29747945..29747955,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:29747945..29747955, -
3.49e-79FFCP PHASE1:Hg19::chr4:175041762..175041777,-#_2bcf9c14bc230f53e06a71f014d6800dp2@ENST00000503140
3.49e-79FFCP PHASE2:Hg19::chr2:30142997..30143009,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:30142997..30143009, -
3.49e-79FFCP PHASE1:Hg19::chr4:174930472..174930480,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174930472..174930480, -
3.49e-79FFCP PHASE1:Hg19::chr2:29747945..29747955,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:29747945..29747955, -
3.49e-79FFCP PHASE1:Hg19::chr5:16180927..16180934,-#_2bcf9c14bc230f53e06a71f014d6800dp7@MARCH11
3.49e-79FFCP PHASE2:Hg19::chr13:36045103..36045110,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr13:36045103..36045110, +
3.49e-79FFCP PHASE2:Hg19::chr7:19184929..19184938,-#_2bcf9c14bc230f53e06a71f014d6800dp4@FERD3L
3.49e-79FFCP PHASE2:Hg19::chr4:174930493..174930503,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174930493..174930503, -
3.49e-79FFCP PHASE1:Hg19::chr13:36045103..36045110,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr13:36045103..36045110, +
3.49e-79FFCP PHASE1:Hg19::chr2:16082933..16082942,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:16082933..16082942, +
3.49e-79FFCP PHASE2:Hg19::chr13:37494987..37494992,-#_2bcf9c14bc230f53e06a71f014d6800dp23@SMAD9
3.49e-79FFCP PHASE1:Hg19::chr7:19185559..19185569,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:19185559..19185569, -
3.49e-79FFCP PHASE1:Hg19::chr13:37494987..37494992,-#_2bcf9c14bc230f53e06a71f014d6800dp23@SMAD9
3.49e-79FFCP PHASE2:Hg19::chr7:19185585..19185590,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:19185585..19185590, -
3.49e-79FFCP PHASE2:Hg19::chr4:174968748..174968753,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174968748..174968753, +
3.49e-79FFCP PHASE2:Hg19::chr2:29894082..29894092,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:29894082..29894092, -
3.49e-79FFCP PHASE1:Hg19::chr2:29894082..29894092,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:29894082..29894092, -
3.49e-79FFCP PHASE1:Hg19::chr2:30142997..30143009,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr2:30142997..30143009, -
3.49e-79FFCP PHASE1:Hg19::chr18:56886837..56886844,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr18:56886837..56886844, +
3.49e-79FFCP PHASE1:Hg19::chr7:19184929..19184938,-#_2bcf9c14bc230f53e06a71f014d6800dp4@FERD3L
3.49e-79FFCP PHASE1:Hg19::chr4:174930493..174930503,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174930493..174930503, -
3.49e-79FFCP PHASE2:Hg19::chr7:19185044..19185056,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr7:19185044..19185056, +
3.49e-79FFCP PHASE2:Hg19::chr4:174930547..174930558,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr4:174930547..174930558, -
3.49e-79FFCP PHASE2:Hg19::chr12:85380546..85380557,+#_2bcf9c14bc230f53e06a71f014d6800dp@chr12:85380546..85380557, +
3.49e-79FFCP PHASE2:Hg19::chr17:74540293..74540300,+#_2bcf9c14bc230f53e06a71f014d6800dp15@PRCD
3.49e-79FFCP PHASE2:Hg19::chr1:22696471..22696505,-#_2bcf9c14bc230f53e06a71f014d6800dp@chr1:22696471..22696505, -










Property "Property value" (as page type) with input value "UBPROP:0000001 "Part of the autonomic nervous system which has opposing physiological effects of the parasympathetic nervous system. Examples include increasing the heart rate or constricting the blood vessels.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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