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UBERON:0002072

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Name:hypodermis
Definition:"Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA]." [Wikipedia:Hypodermis, ZFIN:curator]
Xrefs:
links:

BTO:0004525
FMA:70544
FMA:9630
GAID:929
[ 200px-Skin.svg.png 200px-Skin.svg.png]
MESH:A.10.165.887
ncithesaurus:Superficial_Fascia
TAO:0001136

ZFA:0001136
Synonyms: "hypoderm" EXACT []
"subcutaneous tissue" RELATED [Wikipedia:Hypodermis]
"subcutis" RELATED []
"superficial fascia" EXACT [FMA:9630]
"tela subcutanea" EXACT [FMA:9630, FMA:TA]
"vertebrate hypodermis" EXACT []
Comments:Note that this class combines superficial fascia and hypodermis in FMA. Note also BTO has 'subcutis'
Alt_id: UBERON:FMA_70544-MIAA_0000418-ZFA_0000117-ZFA_0001136
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0002384(connective tissue),UBERON:0004120(mesoderm-derived structure)
develops_from:UBERON:0000926(mesoderm)
part_of:UBERON:0002199(integument)



Children

part of:UBERON:0002190 (subcutaneous adipose tissue),CL:0002583 (subcutaneous preadipocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002072 (hypodermis), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.65e-59FFCP PHASE2:Hg19::chr17:17495407..17495419,-#_3482fd1f80f4be15f00c068e52198d69p17@PEMT
1.65e-59FFCP PHASE1:Hg19::chr17:17495407..17495419,-#_3482fd1f80f4be15f00c068e52198d69p17@PEMT
2.73e-51FFCP PHASE1:Hg19::chr11:111895969..111895977,+#_b5bca8fa9804903ee66f328357721858p8@DLAT
2.73e-51FFCP PHASE2:Hg19::chr11:111895969..111895977,+#_b5bca8fa9804903ee66f328357721858p8@DLAT
3.24e-51FFCP PHASE2:Hg19::chr3:12190006..12190011,+#_e1ad457e1c2540c0d49c8f77c4c08a9bp19@SYN2
3.24e-51FFCP PHASE1:Hg19::chr3:12190006..12190011,+#_e1ad457e1c2540c0d49c8f77c4c08a9bp19@SYN2
3.47e-45FFCP PHASE2:Hg19::chr11:823806..823819,+#_c1704ca19a80a59a25b03e4ef764e991p19@PNPLA2
3.47e-45FFCP PHASE1:Hg19::chr11:823806..823819,+#_c1704ca19a80a59a25b03e4ef764e991p19@PNPLA2
8.55e-45FFCP PHASE2:Hg19::chr11:35232781..35232791,+#_3f95c05a4941784c7b1bb78882b244bdp1@U94903
8.55e-45FFCP PHASE1:Hg19::chr11:35232781..35232791,+#_3f95c05a4941784c7b1bb78882b244bdp1@U94903
1.48e-40FFCP PHASE1:Hg19::chr12:94286185..94286186,+#_3561c89d6970736877bdf353b6c12c81p@chr12:94286185..94286186, +
1.48e-40FFCP PHASE1:Hg19::chr14:66872597..66872598,+#_3561c89d6970736877bdf353b6c12c81p@chr14:66872597..66872598, +
1.48e-40FFCP PHASE2:Hg19::chr12:94286185..94286186,+#_3561c89d6970736877bdf353b6c12c81p@chr12:94286185..94286186, +
1.48e-40FFCP PHASE2:Hg19::chr14:66872597..66872598,+#_3561c89d6970736877bdf353b6c12c81p@chr14:66872597..66872598, +
2.22e-40FFCP PHASE2:Hg19::chr12:109593033..109593052,+#_cde5c832ae3e73e236e67a2d275b5014p@chr12:109593033..109593052, +
2.22e-40FFCP PHASE1:Hg19::chr12:109593033..109593052,+#_cde5c832ae3e73e236e67a2d275b5014p@chr12:109593033..109593052, +
2.55e-40FFCP PHASE2:Hg19::chr12:50503990..50504003,+#_4dd1f169e97385c6eb7c66d8b5b4290dp@chr12:50503990..50504003, +
2.55e-40FFCP PHASE1:Hg19::chr12:50503990..50504003,+#_4dd1f169e97385c6eb7c66d8b5b4290dp@chr12:50503990..50504003, +
3.31e-40FFCP PHASE2:Hg19::chr2:65356996..65357005,+#_6e57ddfd9cfe4b2411e7c1d6b31502c5p@chr2:65356996..65357005, +
3.31e-40FFCP PHASE2:Hg19::chr3:52269260..52269269,-#_6e57ddfd9cfe4b2411e7c1d6b31502c5p@chr3:52269260..52269269, -
3.31e-40FFCP PHASE1:Hg19::chr2:65356996..65357005,+#_6e57ddfd9cfe4b2411e7c1d6b31502c5p@chr2:65356996..65357005, +
3.31e-40FFCP PHASE1:Hg19::chr3:52269260..52269269,-#_6e57ddfd9cfe4b2411e7c1d6b31502c5p@chr3:52269260..52269269, -
4.05e-40FFCP PHASE2:Hg19::chr12:16758109..16758118,-#_0c7d773d7f8edd4d7d59bae69735d596p37@LMO3
4.05e-40FFCP PHASE1:Hg19::chr12:16758109..16758118,-#_0c7d773d7f8edd4d7d59bae69735d596p37@LMO3
1.57e-36FFCP PHASE1:Hg19::chr17:80382262..80382282,+#_00997d7c389106aea03c93158e43997ap@chr17:80382262..80382282, +
1.57e-36FFCP PHASE2:Hg19::chr17:80382262..80382282,+#_00997d7c389106aea03c93158e43997ap@chr17:80382262..80382282, +
6.67e-36FFCP PHASE1:Hg19::chr1:115822948..115822957,+#_7c2b4e41248578e5cb2badeb08a14dc0p@chr1:115822948..115822957, +
6.67e-36FFCP PHASE2:Hg19::chr1:115822948..115822957,+#_7c2b4e41248578e5cb2badeb08a14dc0p@chr1:115822948..115822957, +
2.49e-33FFCP PHASE2:Hg19::chr3:13610185..13610194,+#_549342eb9ba748a786378fe5e4c1b1dap9@FBLN2
2.49e-33FFCP PHASE1:Hg19::chr3:13610185..13610194,+#_549342eb9ba748a786378fe5e4c1b1dap9@FBLN2
6.67e-33FFCP PHASE1:Hg19::chr9:653255..653267,+#_b9f40dab6de1e8815d7a79f26f707bf8p@chr9:653255..653267, +
6.67e-33FFCP PHASE2:Hg19::chr9:653255..653267,+#_b9f40dab6de1e8815d7a79f26f707bf8p@chr9:653255..653267, +
1.23e-32FFCP PHASE1:Hg19::chr5:180258514..180258515,-#_f61b0176585857130581f9cafc667da4p15@uc003mmj.1
1.23e-32FFCP PHASE2:Hg19::chr5:180258514..180258515,-#_f61b0176585857130581f9cafc667da4p15@uc003mmj.1
1.44e-32FFCP PHASE2:Hg19::chr11:111896693..111896701,+#_5094fa46c385b1d90bc5782ef81e7bbcp@chr11:111896693..111896701, +
1.44e-32FFCP PHASE1:Hg19::chr11:111896693..111896701,+#_5094fa46c385b1d90bc5782ef81e7bbcp@chr11:111896693..111896701, +
1.05e-30FFCP PHASE2:Hg19::chr3:52821997..52822012,+#_20c55b3d1ac6647b01661e06b4a6b739p3@ITIH1
1.05e-30FFCP PHASE1:Hg19::chr3:52821997..52822012,+#_20c55b3d1ac6647b01661e06b4a6b739p3@ITIH1
1.73e-30FFCP PHASE2:Hg19::chr3:12190041..12190062,+#_f45386412fcf6a0e7a95c37de619d104p6@SYN2
1.73e-30FFCP PHASE1:Hg19::chr3:12190041..12190062,+#_f45386412fcf6a0e7a95c37de619d104p6@SYN2
1.91e-28FFCP PHASE2:Hg19::chr11:63273651..63273660,+#_70ae755b26d0a7f7becfc218d3a414a2p7@LGALS12
1.91e-28FFCP PHASE1:Hg19::chr11:63273651..63273660,+#_70ae755b26d0a7f7becfc218d3a414a2p7@LGALS12
2.77e-28FFCP PHASE1:Hg19::chr16:68325453..68325473,+#_b496c20a0fe7f58369b75008d6c86f2bp@chr16:68325453..68325473, +
2.77e-28FFCP PHASE2:Hg19::chr16:68325453..68325473,+#_b496c20a0fe7f58369b75008d6c86f2bp@chr16:68325453..68325473, +
1.59e-27FFCP PHASE2:Hg19::chr17:41004526..41004533,-#_90039d72e6a2f90b2752375365440099p@chr17:41004526..41004533, -
1.59e-27FFCP PHASE1:Hg19::chr17:41004526..41004533,-#_90039d72e6a2f90b2752375365440099p@chr17:41004526..41004533, -
1.82e-27FFCP PHASE2:Hg19::chr3:52821979..52821984,+#_2651feab082b9c5b2e7c00584e13de7fp14@ITIH1
1.82e-27FFCP PHASE1:Hg19::chr3:52821979..52821984,+#_2651feab082b9c5b2e7c00584e13de7fp14@ITIH1
2.08e-27FFCP PHASE2:Hg19::chr11:111896671..111896691,+#_d5c40c9b3471a83b1bec87c817902fe3p@chr11:111896671..111896691, +
2.08e-27FFCP PHASE1:Hg19::chr11:111896671..111896691,+#_d5c40c9b3471a83b1bec87c817902fe3p@chr11:111896671..111896691, +
2.08e-27FFCP PHASE2:Hg19::chr10:113915737..113915754,-#_d5c40c9b3471a83b1bec87c817902fe3p@chr10:113915737..113915754, -
2.08e-27FFCP PHASE1:Hg19::chr10:113915737..113915754,-#_d5c40c9b3471a83b1bec87c817902fe3p@chr10:113915737..113915754, -
2.08e-27FFCP PHASE2:Hg19::chr11:63273968..63273973,+#_d5c40c9b3471a83b1bec87c817902fe3p12@LGALS12
2.08e-27FFCP PHASE1:Hg19::chr11:63273968..63273973,+#_d5c40c9b3471a83b1bec87c817902fe3p12@LGALS12
2.19e-27FFCP PHASE1:Hg19::chr1:219632507..219632553,-#_55c61452584793f3ce1b6462e982c5e9p@chr1:219632507..219632553, -
2.19e-27FFCP PHASE2:Hg19::chr1:219632507..219632553,-#_55c61452584793f3ce1b6462e982c5e9p@chr1:219632507..219632553, -
2.72e-27FFCP PHASE1:Hg19::chr15:83330983..83330997,-#_2180086863926c3afbc0cbfb36dc32e6p10@AP3B2
2.72e-27FFCP PHASE2:Hg19::chr15:83330983..83330997,-#_2180086863926c3afbc0cbfb36dc32e6p10@AP3B2
3.11e-27FFCP PHASE2:Hg19::chr17:41003146..41003150,+#_fb672d1d01fed62f0c4d1ca8ef8a365ep6@AOC3
3.11e-27FFCP PHASE1:Hg19::chr5:150138790..150138796,-#_fb672d1d01fed62f0c4d1ca8ef8a365ep18@DCTN4
3.11e-27FFCP PHASE2:Hg19::chr20:61368258..61368275,+#_fb672d1d01fed62f0c4d1ca8ef8a365ep@chr20:61368258..61368275, +
3.11e-27FFCP PHASE2:Hg19::chr5:150138790..150138796,-#_fb672d1d01fed62f0c4d1ca8ef8a365ep18@DCTN4
3.11e-27FFCP PHASE1:Hg19::chr17:41003146..41003150,+#_fb672d1d01fed62f0c4d1ca8ef8a365ep6@AOC3
3.11e-27FFCP PHASE1:Hg19::chr20:61368258..61368275,+#_fb672d1d01fed62f0c4d1ca8ef8a365ep@chr20:61368258..61368275, +
4.02e-27FFCP PHASE2:Hg19::chr10:90750752..90750755,-#_344600eca6b5c4a821441b0f68eecff5p14@ACTA2
4.02e-27FFCP PHASE1:Hg19::chr10:90750752..90750755,-#_344600eca6b5c4a821441b0f68eecff5p14@ACTA2
4.06e-27FFCP PHASE2:Hg19::chr8:27023434..27023437,-#_1445fd38bf23d0e6ca89eb03f2b03e16p@chr8:27023434..27023437, -
4.06e-27FFCP PHASE1:Hg19::chr8:27023434..27023437,-#_1445fd38bf23d0e6ca89eb03f2b03e16p@chr8:27023434..27023437, -
6.28e-25FFCP PHASE1:Hg19::chr5:76435093..76435109,+#_5b929b3e15083a700b52c35aebebcf48p1@ENST00000511547, p1@ENST00000515356
6.28e-25FFCP PHASE2:Hg19::chr5:76435093..76435109,+#_5b929b3e15083a700b52c35aebebcf48p1@ENST00000511547, p1@ENST00000515356
1.29e-24FFCP PHASE1:Hg19::chrX:2670209..2670230,+#_d5bde80b587db5befaa53a04e6193390p3@XG
1.29e-24FFCP PHASE2:Hg19::chrX:2670209..2670230,+#_d5bde80b587db5befaa53a04e6193390p3@XG
1.41e-24FFCP PHASE2:Hg19::chr3:9911748..9911751,-#_93c93384e38ef9dfb48bf6163245dc26p@chr3:9911748..9911751, -
1.41e-24FFCP PHASE1:Hg19::chr3:9911748..9911751,-#_93c93384e38ef9dfb48bf6163245dc26p@chr3:9911748..9911751, -
1.94e-24FFCP PHASE2:Hg19::chr3:186575301..186575315,+#_0a634b51bcaea85f9b4163e9bc716096p@chr3:186575301..186575315, +
1.94e-24FFCP PHASE1:Hg19::chr3:186575301..186575315,+#_0a634b51bcaea85f9b4163e9bc716096p@chr3:186575301..186575315, +
2.1e-24FFCP PHASE1:Hg19::chr7:155044107..155044121,-#_51d8b7d9e30b117da446468394365591p@chr7:155044107..155044121, -
2.1e-24FFCP PHASE2:Hg19::chr7:155044107..155044121,-#_51d8b7d9e30b117da446468394365591p@chr7:155044107..155044121, -
1.02e-23FFCP PHASE2:Hg19::chrX:151999438..151999444,-#_d85dfb176d51f0deb913f8532f1e2186p3@CETN2
1.02e-23FFCP PHASE1:Hg19::chrX:151999438..151999444,-#_d85dfb176d51f0deb913f8532f1e2186p3@CETN2
1.14e-23FFCP PHASE2:Hg19::chr1:109939715..109939728,+#_dfad43f9d211631b496c16634bd7862bp@chr1:109939715..109939728, +
1.14e-23FFCP PHASE1:Hg19::chr1:109939715..109939728,+#_dfad43f9d211631b496c16634bd7862bp@chr1:109939715..109939728, +
1.28e-23FFCP PHASE1:Hg19::chr11:77775063..77775072,+#_dfbe016002f176110a976761481ac740p4@THRSP
1.28e-23FFCP PHASE2:Hg19::chr11:77775063..77775072,+#_dfbe016002f176110a976761481ac740p4@THRSP
1.28e-23FFCP PHASE1:Hg19::chr1:236205344..236205359,-#_dfbe016002f176110a976761481ac740p@chr1:236205344..236205359, -
1.28e-23FFCP PHASE2:Hg19::chr19:4512807..4512811,-#_dfbe016002f176110a976761481ac740p2@PLIN4
1.28e-23FFCP PHASE2:Hg19::chr1:236205344..236205359,-#_dfbe016002f176110a976761481ac740p@chr1:236205344..236205359, -
1.28e-23FFCP PHASE1:Hg19::chr19:4512807..4512811,-#_dfbe016002f176110a976761481ac740p2@PLIN4
1.44e-23FFCP PHASE2:Hg19::chr13:36706070..36706078,-#_fbec1f5e3481591764f5f1cdefac3cb9p@chr13:36706070..36706078, -
1.44e-23FFCP PHASE1:Hg19::chr13:36706070..36706078,-#_fbec1f5e3481591764f5f1cdefac3cb9p@chr13:36706070..36706078, -
1.61e-23FFCP PHASE1:Hg19::chr10:53458769..53458785,+#_63b8c57103e83b8ec0736b72ffa6921cp@chr10:53458769..53458785, +
1.61e-23FFCP PHASE2:Hg19::chr10:53458769..53458785,+#_63b8c57103e83b8ec0736b72ffa6921cp@chr10:53458769..53458785, +
1.87e-23FFCP PHASE2:Hg19::chr3:13610216..13610265,+#_c787e9027c07bc75d7df564cec4b29e2p3@FBLN2
1.87e-23FFCP PHASE1:Hg19::chr3:13610216..13610265,+#_c787e9027c07bc75d7df564cec4b29e2p3@FBLN2
1.9e-23FFCP PHASE2:Hg19::chr3:52822026..52822045,+#_f5b14ec3919eec24f06475fdea567e15p2@ITIH1
1.9e-23FFCP PHASE1:Hg19::chr3:52822026..52822045,+#_f5b14ec3919eec24f06475fdea567e15p2@ITIH1
6.02e-23FFCP PHASE2:Hg19::chr2:238273001..238273016,+#_813c2f8307bc48041ee1cd178c2aeb53p@chr2:238273001..238273016, +
6.02e-23FFCP PHASE1:Hg19::chr2:238273001..238273016,+#_813c2f8307bc48041ee1cd178c2aeb53p@chr2:238273001..238273016, +
7.94e-23FFCP PHASE1:Hg19::chr9:34590839..34590855,-#_fb47b7b9a04e8ea90c77c7775adebb6fp@chr9:34590839..34590855, -
7.94e-23FFCP PHASE2:Hg19::chr9:34590839..34590855,-#_fb47b7b9a04e8ea90c77c7775adebb6fp@chr9:34590839..34590855, -