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Coexpression cluster:C4391

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Full id: C4391_mucinous_mesenchymal_Preadipocyte_stomach_Mesothelial_Smooth_duodenum



Phase1 CAGE Peaks

Hg19::chr4:169013681..169013697,+p1@ANXA10
Hg19::chr4:169013698..169013709,+p3@ANXA10
Hg19::chr4:169013766..169013773,+p5@ANXA10


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
systemic artery2.97e-1633
systemic arterial system2.97e-1633
artery2.45e-1542
arterial blood vessel2.45e-1542
arterial system2.45e-1542
muscle tissue2.73e-1563
musculature2.73e-1563
musculature of body2.73e-1563
skeletal muscle tissue5.90e-1461
striated muscle tissue5.90e-1461
myotome5.90e-1461
unilaminar epithelium8.10e-12138
trunk mesenchyme1.14e-11143
dermomyotome4.66e-1170
multilaminar epithelium8.91e-1082
blood vessel1.37e-0960
epithelial tube open at both ends1.37e-0960
blood vasculature1.37e-0960
vascular cord1.37e-0960
epithelial tube1.60e-09118
somite1.74e-0983
paraxial mesoderm1.74e-0983
presomitic mesoderm1.74e-0983
presumptive segmental plate1.74e-0983
trunk paraxial mesoderm1.74e-0983
presumptive paraxial mesoderm1.74e-0983
trunk3.56e-09216
splanchnic layer of lateral plate mesoderm9.17e-0984
vasculature1.79e-0879
vascular system1.79e-0879
mesenchyme3.72e-08238
entire embryonic mesenchyme3.72e-08238
heart blood vessel3.84e-085
coronary vessel3.84e-085
smooth muscle tissue5.24e-0815
genitourinary system6.57e-0815
vessel1.82e-0769
prostate gland4.46e-0711
male accessory sex gland4.46e-0711
embryonic cloacal epithelium4.46e-0711
epithelium of hindgut4.46e-0711
urogenital sinus epithelium4.46e-0711
prostate bud4.46e-0711
prostate field4.46e-0711
aorta5.27e-0721
aortic system5.27e-0721
artery wall5.75e-074
tunica adventitia of artery5.75e-074
adventitia5.75e-074
tunica adventitia of blood vessel5.75e-074
aorta tunica adventitia5.75e-074
aorta wall5.75e-074
cloaca9.15e-0714
anal region9.15e-0714
embryonic cloaca9.15e-0714
terminal part of digestive tract9.15e-0714
primitive urogenital sinus9.15e-0714
proctodeum9.15e-0714
Disease
Ontology termp-valuen
ovarian cancer3.79e-1014


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.