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Coexpression cluster:C3589

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Full id: C3589_pineal_Reticulocytes_putamen_amygdala_medial_cerebellum_occipital



Phase1 CAGE Peaks

Hg19::chr16:75681623..75681648,+p3@TERF2IP
Hg19::chr16:75681650..75681696,+p2@TERF2IP
Hg19::chr16:75681700..75681764,+p1@TERF2IP


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.06e-39115
neural tube2.73e-3257
neural rod2.73e-3257
future spinal cord2.73e-3257
neural keel2.73e-3257
regional part of brain7.70e-2959
central nervous system3.12e-2882
regional part of nervous system6.99e-2894
nervous system6.99e-2894
neural plate7.24e-2886
presumptive neural plate7.24e-2886
brain5.46e-2769
future brain5.46e-2769
neurectoderm5.07e-2690
regional part of forebrain5.33e-2441
forebrain5.33e-2441
future forebrain5.33e-2441
anterior neural tube6.34e-2442
pre-chordal neural plate1.52e-2061
gray matter1.34e-1934
brain grey matter1.34e-1934
telencephalon1.37e-1934
regional part of telencephalon6.09e-1933
cerebral hemisphere1.70e-1832
anterior region of body8.51e-17129
craniocervical region8.51e-17129
head1.39e-15123
ectoderm-derived structure6.96e-15169
regional part of cerebral cortex9.39e-1522
cerebral cortex3.24e-1425
pallium3.24e-1425
ectoderm3.34e-14173
presumptive ectoderm3.34e-14173
neocortex1.29e-1320
posterior neural tube2.02e-0915
chordal neural plate2.02e-0915
segmental subdivision of nervous system3.01e-0813
segmental subdivision of hindbrain7.55e-0812
hindbrain7.55e-0812
presumptive hindbrain7.55e-0812
basal ganglion6.16e-079
nuclear complex of neuraxis6.16e-079
aggregate regional part of brain6.16e-079
collection of basal ganglia6.16e-079
cerebral subcortex6.16e-079
nucleus of brain6.98e-079
neural nucleus6.98e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.