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Coexpression cluster:C3052

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Full id: C3052_testis_corpus_spinal_thalamus_pons_optic_diencephalon



Phase1 CAGE Peaks

Hg19::chr10:86211964..86211988,+p5@FAM190B
Hg19::chr11:111749942..111749989,+p3@C11orf1
Hg19::chr8:18666347..18666356,-p26@PSD3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.25e-2757
neural rod1.25e-2757
future spinal cord1.25e-2757
neural keel1.25e-2757
regional part of nervous system3.86e-2794
nervous system3.86e-2794
central nervous system5.33e-2782
regional part of brain4.11e-2359
adult organism5.92e-22115
brain8.69e-2269
future brain8.69e-2269
regional part of forebrain8.17e-2141
forebrain8.17e-2141
future forebrain8.17e-2141
anterior neural tube1.96e-2042
neurectoderm1.81e-1990
neural plate3.16e-1986
presumptive neural plate3.16e-1986
telencephalon3.54e-1734
gray matter3.75e-1734
brain grey matter3.75e-1734
ectoderm5.40e-17173
presumptive ectoderm5.40e-17173
ectoderm-derived structure1.35e-16169
regional part of telencephalon1.51e-1633
cerebral hemisphere7.29e-1632
pre-chordal neural plate5.68e-1561
head8.05e-14123
anterior region of body2.68e-13129
craniocervical region2.68e-13129
regional part of cerebral cortex9.56e-1222
cerebral cortex1.17e-1125
pallium1.17e-1125
neocortex1.34e-1020
posterior neural tube2.46e-0815
chordal neural plate2.46e-0815
nucleus of brain3.68e-079
neural nucleus3.68e-079
segmental subdivision of nervous system3.89e-0713
basal ganglion5.18e-079
nuclear complex of neuraxis5.18e-079
aggregate regional part of brain5.18e-079
collection of basal ganglia5.18e-079
cerebral subcortex5.18e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.