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Coexpression cluster:C1794

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Full id: C1794_heart_Cardiac_seminal_umbilical_ductus_Smooth_left



Phase1 CAGE Peaks

Hg19::chr17:77018850..77018871,+p@chr17:77018850..77018871
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Hg19::chr17:77018898..77018919,+p@chr17:77018898..77018919
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Hg19::chr17:77018953..77018966,+p@chr17:77018953..77018966
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Hg19::chr17:77018991..77019000,+p@chr17:77018991..77019000
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Hg19::chr17:77019002..77019027,+p@chr17:77019002..77019027
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
primary circulatory organ5.59e-3727
heart1.68e-3224
primitive heart tube1.68e-3224
primary heart field1.68e-3224
anterior lateral plate mesoderm1.68e-3224
heart tube1.68e-3224
heart primordium1.68e-3224
cardiac mesoderm1.68e-3224
cardiogenic plate1.68e-3224
heart rudiment1.68e-3224
adult organism3.36e-28115
compound organ1.48e-2269
splanchnic layer of lateral plate mesoderm2.04e-2284
epithelial tube1.91e-19118
circulatory system7.46e-17113
anatomical conduit2.23e-16241
tube5.03e-16194
anatomical cluster1.03e-14286
cardiovascular system1.80e-14110
muscle tissue7.98e-1263
musculature7.98e-1263
musculature of body7.98e-1263
multi-tissue structure1.87e-11347
skeletal muscle tissue9.86e-1161
striated muscle tissue9.86e-1161
myotome9.86e-1161
systemic artery1.49e-1033
systemic arterial system1.49e-1033
epithelium1.51e-10309
artery2.58e-1042
arterial blood vessel2.58e-1042
arterial system2.58e-1042
cell layer3.09e-10312
blood vessel1.02e-0960
epithelial tube open at both ends1.02e-0960
blood vasculature1.02e-0960
vascular cord1.02e-0960
trunk1.13e-09216
primordium6.02e-09168
dermomyotome2.55e-0870
vessel2.74e-0869
trunk mesenchyme6.86e-08143
heart blood vessel8.15e-085
coronary vessel8.15e-085
mesenchyme9.33e-08238
entire embryonic mesenchyme9.33e-08238
vasculature1.74e-0779
vascular system1.74e-0779
multi-cellular organism2.13e-07659
organism subdivision5.23e-07365
unilaminar epithelium7.96e-07138


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.