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Coexpression cluster:C1520

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Full id: C1520_cerebellum_parietal_occipital_temporal_duodenum_middle_thymus



Phase1 CAGE Peaks

Hg19::chr4:21381485..21381488,-p@chr4:21381485..21381488
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Hg19::chr7:71362939..71362942,-p@chr7:71362939..71362942
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Hg19::chr7:71557606..71557611,-p@chr7:71557606..71557611
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Hg19::chr8:10306708..10306725,+p@chr8:10306708..10306725
+
Hg19::chr8:10307650..10307657,+p@chr8:10307650..10307657
+
Hg19::chr8:9761063..9761074,-p3@MIR124-1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube8.96e-3957
neural rod8.96e-3957
future spinal cord8.96e-3957
neural keel8.96e-3957
central nervous system8.17e-3782
regional part of nervous system5.82e-3594
nervous system5.82e-3594
regional part of forebrain6.63e-3241
forebrain6.63e-3241
future forebrain6.63e-3241
brain1.38e-3169
future brain1.38e-3169
regional part of brain1.39e-3159
anterior neural tube8.86e-3142
neurectoderm1.09e-2690
gray matter6.01e-2634
brain grey matter6.01e-2634
telencephalon9.74e-2634
neural plate2.71e-2586
presumptive neural plate2.71e-2586
regional part of telencephalon8.95e-2533
cerebral hemisphere2.97e-2432
adult organism3.43e-22115
regional part of cerebral cortex1.04e-2122
pre-chordal neural plate5.84e-2061
cerebral cortex9.86e-2025
pallium9.86e-2025
neocortex1.39e-1920
ectoderm6.18e-16173
presumptive ectoderm6.18e-16173
ectoderm-derived structure7.92e-15169
anterior region of body3.05e-14129
craniocervical region3.05e-14129
head2.46e-13123
posterior neural tube4.32e-0915
chordal neural plate4.32e-0915
basal ganglion5.86e-089
nuclear complex of neuraxis5.86e-089
aggregate regional part of brain5.86e-089
collection of basal ganglia5.86e-089
cerebral subcortex5.86e-089
segmental subdivision of nervous system1.12e-0713
nucleus of brain1.21e-079
neural nucleus1.21e-079
gyrus1.25e-076
diencephalon1.36e-077
future diencephalon1.36e-077
temporal lobe2.24e-077
segmental subdivision of hindbrain7.37e-0712
hindbrain7.37e-0712
presumptive hindbrain7.37e-0712


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.