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Coexpression cluster:C1137

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Full id: C1137_CD4_CD8_thymus_Natural_blood_Whole_Peripheral



Phase1 CAGE Peaks

Hg19::chr11:14671615..14671618,+p@chr11:14671615..14671618
+
Hg19::chr14:105944163..105944184,+p@chr14:105944163..105944184
+
Hg19::chr14:22265481..22265487,+p5@TRAV8-1
Hg19::chr4:109088233..109088240,-p62@LEF1
Hg19::chr5:133449741..133449744,-p@chr5:133449741..133449744
-
Hg19::chr7:142021271..142021284,+p1@AF020656
p1@AF325867
p1@AF395795
p1@AY611551
p1@AY751843
p1@AY751887
p1@AY751915
p1@EF592002
p1@GQ502881
p1@GQ502883
p1@HM236508
p1@HM236510
p1@HM236512
p1@HM236514
p1@HM236515
p1@HM236544
p1@HM236615
p1@HM236635
p1@HM236642
p1@HM236659
p1@HM236662
p1@HM236673
p1@HM236674
p1@HM236676
p1@HM236718
p1@HM236776
p1@HM236777
p1@HM236807
p1@HM467843
p1@HM467856
p1@HM467875
p1@HM467876
p1@HM467877
p1@HM467878
p1@JF731146
p1@JF731148
p1@JF731150
Hg19::chrX:11776810..11776821,+p17@MSL3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.