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CL:0002677

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Name:naive regulatory T cell
Namespace:cell
Definition:"A regulatory T cell that has not encountered antigen." [GOC:tfm]
Comments:This cell type has been described as CD45RA-negative, but this doesn't fit with our current definition of naive T cell.
Created by:tmeehan
Creation date:2011-08-25T03:17:21Z


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000792(CD4-positive, CD25-positive, alpha-beta regulatory T cell),CL:0000898(naive T cell)



Children


is a:FF:0011127 (CD4-positiveCD25-positiveCD45RA- naive regulatory T cells expanded),FF:11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1),FF:11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
derives from:FF:0011128 (human CD4-positiveCD25-positiveCD45RA- naive regulatory T cells sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)

Mouse (Mus musculus)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002677 (naive regulatory T cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
4.61e-131FFCP PHASE1:Hg19::chr1:113160702..113160706,-#_68c8bf854f3083761ccaf4945f930d9fp21@ST7L
4.61e-131FFCP PHASE2:Hg19::chr1:113160702..113160706,-#_68c8bf854f3083761ccaf4945f930d9fp21@ST7L
5.68e-99FFCP PHASE1:Hg19::chr11:111410267..111410269,+#_ce87f1a7fd4facdab8d60dad3343c472p@chr11:111410267..111410269, +
5.68e-99FFCP PHASE2:Hg19::chr11:111410267..111410269,+#_ce87f1a7fd4facdab8d60dad3343c472p@chr11:111410267..111410269, +
1.55e-98FFCP PHASE1:Hg19::chr3:73015629..73015632,+#_d544f4621466933ee6afa55cc614a23cp@chr3:73015629..73015632, +
1.55e-98FFCP PHASE2:Hg19::chr3:73015629..73015632,+#_d544f4621466933ee6afa55cc614a23cp@chr3:73015629..73015632, +
1.05e-79FFCP PHASE2:Hg19::chr6:138115457..138115471,+#_67397f9b6520f63aa509bdd4a2606fe3p@chr6:138115457..138115471, +
1.05e-79FFCP PHASE1:Hg19::chr6:138115457..138115471,+#_67397f9b6520f63aa509bdd4a2606fe3p@chr6:138115457..138115471, +
5.22e-79FFCP PHASE1:Hg19::chr7:142013392..142013402,+#_cbf9996739135afb6d442537a1d69d09p1@AF428125, p1@AF428127, p1@AY123171, p1@AY123177, p1@AY123180, p1@AY123183, p1@AY190091, p1@AY190112, p1@AY751872, p1@DQ875564, p1@EF592013, p1@S79336
5.22e-79FFCP PHASE2:Hg19::chr7:142013392..142013402,+#_cbf9996739135afb6d442537a1d69d09p1@AF428125, p1@AF428127, p1@AY123171, p1@AY123177, p1@AY123180, p1@AY123183, p1@AY190091, p1@AY190112, p1@AY751872, p1@DQ875564, p1@EF592013, p1@S79336
1.04e-66FFCP PHASE1:Hg19::chr2:69871669..69871678,+#_216955f300f9e2fcc375644d5b33a085p9@ENST00000418066
1.04e-66FFCP PHASE1:Hg19::chr19:42145518..42145524,+#_216955f300f9e2fcc375644d5b33a085p@chr19:42145518..42145524, +
1.04e-66FFCP PHASE2:Hg19::chr2:69871669..69871678,+#_216955f300f9e2fcc375644d5b33a085p9@ENST00000418066
1.04e-66FFCP PHASE2:Hg19::chr19:42145518..42145524,+#_216955f300f9e2fcc375644d5b33a085p@chr19:42145518..42145524, +
1.45e-66FFCP PHASE1:Hg19::chr19:42132832..42132865,+#_8bb7c1bf6f96f3aef6d56910f52aa2dbp@chr19:42132832..42132865, +
1.45e-66FFCP PHASE2:Hg19::chr19:42132832..42132865,+#_8bb7c1bf6f96f3aef6d56910f52aa2dbp@chr19:42132832..42132865, +
2.84e-66FFCP PHASE2:Hg19::chr10:17697543..17697546,-#_e5999edf3fbc810b1f33f14c04d281e2p@chr10:17697543..17697546, -
2.84e-66FFCP PHASE1:Hg19::chr10:17697543..17697546,-#_e5999edf3fbc810b1f33f14c04d281e2p@chr10:17697543..17697546, -
2.02e-57FFCP PHASE1:Hg19::chr11:95421442..95421475,-#_431f7da3d3e005e202cf96ef27dfe885p@chr11:95421442..95421475, -
2.02e-57FFCP PHASE1:Hg19::chr18:13382698..13382707,+#_431f7da3d3e005e202cf96ef27dfe885p@chr18:13382698..13382707, +
2.02e-57FFCP PHASE2:Hg19::chr18:13382698..13382707,+#_431f7da3d3e005e202cf96ef27dfe885p@chr18:13382698..13382707, +
2.02e-57FFCP PHASE2:Hg19::chr11:95421442..95421475,-#_431f7da3d3e005e202cf96ef27dfe885p@chr11:95421442..95421475, -
3.58e-57FFCP PHASE1:Hg19::chr12:122239669..122239674,-#_3407db155b376d5b71d17ed5021e2e3dp6@ENST00000535614
3.58e-57FFCP PHASE2:Hg19::chr12:122239669..122239674,-#_3407db155b376d5b71d17ed5021e2e3dp6@ENST00000535614
4.77e-57FFCP PHASE1:Hg19::chr16:22546145..22546152,+#_c443bba229a1b000c8c6f075bec22db8p@chr16:22546145..22546152, +
4.77e-57FFCP PHASE2:Hg19::chr16:22546145..22546152,+#_c443bba229a1b000c8c6f075bec22db8p@chr16:22546145..22546152, +
8.47e-57FFCP PHASE2:Hg19::chr10:24911304..24911311,+#_be73359dc5e472d4ae69746b03285a4ap@chr10:24911304..24911311, +
8.47e-57FFCP PHASE1:Hg19::chr10:24911304..24911311,+#_be73359dc5e472d4ae69746b03285a4ap@chr10:24911304..24911311, +
1.46e-50FFCP PHASE2:Hg19::chr2:213963849..213963858,-#_23c29a3ad10be9ab9cd9b52d3b9d9559p@chr2:213963849..213963858, -
1.46e-50FFCP PHASE2:Hg19::chr21:47035633..47035642,+#_23c29a3ad10be9ab9cd9b52d3b9d9559p@chr21:47035633..47035642, +
1.46e-50FFCP PHASE1:Hg19::chr2:213963849..213963858,-#_23c29a3ad10be9ab9cd9b52d3b9d9559p@chr2:213963849..213963858, -
1.46e-50FFCP PHASE1:Hg19::chr21:47035633..47035642,+#_23c29a3ad10be9ab9cd9b52d3b9d9559p@chr21:47035633..47035642, +
2.42e-50FFCP PHASE1:Hg19::chr1:186287725..186287734,-#_bad55848b2022a10d987f7457334cf68p@chr1:186287725..186287734, -
2.42e-50FFCP PHASE2:Hg19::chr1:186287725..186287734,-#_bad55848b2022a10d987f7457334cf68p@chr1:186287725..186287734, -
2.42e-50FFCP PHASE1:Hg19::chr8:1709009..1709019,-#_bad55848b2022a10d987f7457334cf68p1@BC025336
2.42e-50FFCP PHASE2:Hg19::chr8:1709009..1709019,-#_bad55848b2022a10d987f7457334cf68p1@BC025336
4.52e-50FFCP PHASE1:Hg19::chr7:105441012..105441027,-#_4656ecd56283480a4e92541ff8de696cp@chr7:105441012..105441027, -
4.52e-50FFCP PHASE2:Hg19::chr7:105441012..105441027,-#_4656ecd56283480a4e92541ff8de696cp@chr7:105441012..105441027, -
5.15e-50FFCP PHASE2:Hg19::chr5:14993035..14993045,+#_a0fd645df664b5f79b0146823f0968e6p@chr5:14993035..14993045, +
5.15e-50FFCP PHASE1:Hg19::chr5:14993035..14993045,+#_a0fd645df664b5f79b0146823f0968e6p@chr5:14993035..14993045, +
2.55e-45FFCP PHASE1:Hg19::chrX:153238522..153238533,-#_71da15846bb4808dc1e78b6d5bfb406fp@chrX:153238522..153238533, -
2.55e-45FFCP PHASE2:Hg19::chrX:153238522..153238533,-#_71da15846bb4808dc1e78b6d5bfb406fp@chrX:153238522..153238533, -
3.19e-45FFCP PHASE1:Hg19::chr19:42145229..42145239,+#_35395ca216e7d06790ad0fa8ab70f888p@chr19:42145229..42145239, +
3.19e-45FFCP PHASE2:Hg19::chr3:66444556..66444563,-#_35395ca216e7d06790ad0fa8ab70f888p@chr3:66444556..66444563, -
3.19e-45FFCP PHASE2:Hg19::chr19:42145229..42145239,+#_35395ca216e7d06790ad0fa8ab70f888p@chr19:42145229..42145239, +
3.19e-45FFCP PHASE1:Hg19::chr3:66444556..66444563,-#_35395ca216e7d06790ad0fa8ab70f888p@chr3:66444556..66444563, -
5.0e-45FFCP PHASE1:Hg19::chr8:1708601..1708607,+#_f988e28d427eb4400c25b9f055c2caf7p@chr8:1708601..1708607, +
5.0e-45FFCP PHASE2:Hg19::chr8:1708601..1708607,+#_f988e28d427eb4400c25b9f055c2caf7p@chr8:1708601..1708607, +
6.26e-45FFCP PHASE2:Hg19::chr10:6337053..6337076,+#_fbc36c3ea98846c2799a664c57927d04p@chr10:6337053..6337076, +
6.26e-45FFCP PHASE1:Hg19::chr10:6337053..6337076,+#_fbc36c3ea98846c2799a664c57927d04p@chr10:6337053..6337076, +
7.83e-45FFCP PHASE1:Hg19::chr2:204736259..204736275,-#_fcf3fc9b92b1c26fd73be179323b8476p@chr2:204736259..204736275, -
7.83e-45FFCP PHASE2:Hg19::chr2:204736259..204736275,-#_fcf3fc9b92b1c26fd73be179323b8476p@chr2:204736259..204736275, -
9.79e-45FFCP PHASE2:Hg19::chr11:128199304..128199313,+#_e41f22aae25efaa48960705f82383f80p@chr11:128199304..128199313, +
9.79e-45FFCP PHASE1:Hg19::chr11:128199304..128199313,+#_e41f22aae25efaa48960705f82383f80p@chr11:128199304..128199313, +
7.33e-41FFCP PHASE1:Hg19::chr6:38905902..38905931,+#_4c5367893cc882458ea107b6bfa0713ap@chr6:38905902..38905931, +
7.33e-41FFCP PHASE2:Hg19::chr6:38905902..38905931,+#_4c5367893cc882458ea107b6bfa0713ap@chr6:38905902..38905931, +
8.98e-41FFCP PHASE1:Hg19::chr13:40765017..40765053,-#_ce5ffd433f363711db77dbecad936f3bp@chr13:40765017..40765053, -
8.98e-41FFCP PHASE2:Hg19::chr13:40765017..40765053,-#_ce5ffd433f363711db77dbecad936f3bp@chr13:40765017..40765053, -
1.1e-40FFCP PHASE2:Hg19::chr21:32568033..32568068,-#_55b4e0c74b690b28a43c136062e987d9p@chr21:32568033..32568068, -
1.1e-40FFCP PHASE1:Hg19::chr21:32568033..32568068,-#_55b4e0c74b690b28a43c136062e987d9p@chr21:32568033..32568068, -
1.34e-40FFCP PHASE1:Hg19::chr7:44663908..44663917,+#_8f70c5da8daf429b03d853ddb589bf41p6@OGDH
1.34e-40FFCP PHASE2:Hg19::chr7:44663908..44663917,+#_8f70c5da8daf429b03d853ddb589bf41p6@OGDH
1.64e-40FFCP PHASE1:Hg19::chr1:118201616..118201641,+#_7be82139d9c4b3d60cd9d775c176aa2ep@chr1:118201616..118201641, +
1.64e-40FFCP PHASE2:Hg19::chr1:118201616..118201641,+#_7be82139d9c4b3d60cd9d775c176aa2ep@chr1:118201616..118201641, +
2.01e-40FFCP PHASE2:Hg19::chr10:63977707..63977724,-#_6456dc37ef506043c26ea34367d0c7e5p@chr10:63977707..63977724, -
2.01e-40FFCP PHASE1:Hg19::chr10:63977707..63977724,-#_6456dc37ef506043c26ea34367d0c7e5p@chr10:63977707..63977724, -
3.01e-40FFCP PHASE1:Hg19::chr10:63996620..63996627,-#_c11e3b88460a5307b00b19e0b2d8b581p@chr10:63996620..63996627, -
3.01e-40FFCP PHASE2:Hg19::chrX:49122952..49122962,-#_c11e3b88460a5307b00b19e0b2d8b581p@chrX:49122952..49122962, -
3.01e-40FFCP PHASE1:Hg19::chrX:49122952..49122962,-#_c11e3b88460a5307b00b19e0b2d8b581p@chrX:49122952..49122962, -
3.01e-40FFCP PHASE1:Hg19::chr1:27853648..27853665,-#_c11e3b88460a5307b00b19e0b2d8b581p@chr1:27853648..27853665, -
3.01e-40FFCP PHASE2:Hg19::chr1:27853648..27853665,-#_c11e3b88460a5307b00b19e0b2d8b581p@chr1:27853648..27853665, -
3.01e-40FFCP PHASE2:Hg19::chr10:63996620..63996627,-#_c11e3b88460a5307b00b19e0b2d8b581p@chr10:63996620..63996627, -
3.68e-40FFCP PHASE2:Hg19::chrY:23411674..23411684,+#_02546325b7beaf6db8579e59a6e6a7c7p@chrY:23411674..23411684, +
3.68e-40FFCP PHASE1:Hg19::chrY:23411674..23411684,+#_02546325b7beaf6db8579e59a6e6a7c7p@chrY:23411674..23411684, +
5.49e-40FFCP PHASE2:Hg19::chrX:49107447..49107461,-#_579c85bcf257c818bbd1898354aefd5dp@chrX:49107447..49107461, -
5.49e-40FFCP PHASE1:Hg19::chrX:49107447..49107461,-#_579c85bcf257c818bbd1898354aefd5dp@chrX:49107447..49107461, -
1.3e-37FFCP PHASE2:Hg19::chrX:118822985..118823001,+#_7ae667f84da005293e46a015791720e2p@chrX:118822985..118823001, +
1.3e-37FFCP PHASE1:Hg19::chrX:118822985..118823001,+#_7ae667f84da005293e46a015791720e2p@chrX:118822985..118823001, +
1.57e-37FFCP PHASE2:Hg19::chr3:47079691..47079696,+#_7f74196e33eab0a49919d5e37dbdbd01p@chr3:47079691..47079696, +
1.57e-37FFCP PHASE1:Hg19::chr3:47079691..47079696,+#_7f74196e33eab0a49919d5e37dbdbd01p@chr3:47079691..47079696, +
1.89e-37FFCP PHASE1:Hg19::chr15:63961074..63961079,+#_9a222dffe8d23196ded6ee5bca7bb674p@chr15:63961074..63961079, +
1.89e-37FFCP PHASE2:Hg19::chr15:63961074..63961079,+#_9a222dffe8d23196ded6ee5bca7bb674p@chr15:63961074..63961079, +
2.27e-37FFCP PHASE2:Hg19::chr19:42145174..42145183,+#_320cb1ae9073e06536b1b288afc4dbc6p@chr19:42145174..42145183, +
2.27e-37FFCP PHASE1:Hg19::chr19:42145174..42145183,+#_320cb1ae9073e06536b1b288afc4dbc6p@chr19:42145174..42145183, +
3.28e-37FFCP PHASE2:Hg19::chr3:183067487..183067500,+#_473ec7f0aa3a52649eb59ac345f263f7p@chr3:183067487..183067500, +
3.28e-37FFCP PHASE1:Hg19::chr9:133920899..133920914,+#_473ec7f0aa3a52649eb59ac345f263f7p@chr9:133920899..133920914, +
3.28e-37FFCP PHASE1:Hg19::chr3:183067487..183067500,+#_473ec7f0aa3a52649eb59ac345f263f7p@chr3:183067487..183067500, +
3.28e-37FFCP PHASE2:Hg19::chr9:133920899..133920914,+#_473ec7f0aa3a52649eb59ac345f263f7p@chr9:133920899..133920914, +
3.94e-37FFCP PHASE1:Hg19::chr4:109086375..109086388,-#_2baa939aa4d3b130335122bf8e5d3eccp43@LEF1
3.94e-37FFCP PHASE2:Hg19::chr4:109086375..109086388,-#_2baa939aa4d3b130335122bf8e5d3eccp43@LEF1
3.94e-37FFCP PHASE1:Hg19::chr11:128392481..128392492,+#_2baa939aa4d3b130335122bf8e5d3eccp@chr11:128392481..128392492, +
3.94e-37FFCP PHASE2:Hg19::chr11:128392481..128392492,+#_2baa939aa4d3b130335122bf8e5d3eccp@chr11:128392481..128392492, +
4.73e-37FFCP PHASE1:Hg19::chr14:22443271..22443281,+#_0679b47486fd1c20e156d467e245efa7p@chr14:22443271..22443281, +
4.73e-37FFCP PHASE2:Hg19::chr8:29946317..29946322,+#_0679b47486fd1c20e156d467e245efa7p@chr8:29946317..29946322, +
4.73e-37FFCP PHASE2:Hg19::chr14:22443271..22443281,+#_0679b47486fd1c20e156d467e245efa7p@chr14:22443271..22443281, +
4.73e-37FFCP PHASE1:Hg19::chr8:29946317..29946322,+#_0679b47486fd1c20e156d467e245efa7p@chr8:29946317..29946322, +
6.83e-37FFCP PHASE1:Hg19::chr12:12654246..12654268,-#_bbb6061e7d45e104812b7f733a6760d0p@chr12:12654246..12654268, -
6.83e-37FFCP PHASE2:Hg19::chr12:12654246..12654268,-#_bbb6061e7d45e104812b7f733a6760d0p@chr12:12654246..12654268, -
8.2e-37FFCP PHASE2:Hg19::chr16:50372905..50372915,-#_98bdffc8498615e622730c67295d8f77p@chr16:50372905..50372915, -
8.2e-37FFCP PHASE1:Hg19::chr16:50372905..50372915,-#_98bdffc8498615e622730c67295d8f77p@chr16:50372905..50372915, -